Matches in SemOpenAlex for { <https://semopenalex.org/work/W3176937323> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3176937323 abstract "Abstract Brown macroalgae are an attractive third-generation feedstock of natural products, in order to design green chemistry-compliant processes and reduce the use of organic solvents in bioactive product extraction, aqueous two-phase systems (ATPS) was applied. This research aimed to develop a high-throughput screening (HTS) to recover polyphenols from Ascophyllum nodosum using ATPS. In total, 384 different 2-phase systems were assessed using an automated liquid-handling system to evaluate polyphenol recovery using a model system of phloroglucinol to establish an optimal 2-phase system for polyphenol partitioning. Various ratios of PEG:potassium phosphate solutions were explored to evaluate partitioning of polyphenols via a scale-down approach. Scale-down selected system showed a recovery of phloroglucinol of 62.9±12.0%, this system was used for scale-up trials. Scale-up studies confirmed that the HTS method was able to recover polyphenols with a 54.8±14.2% in the phloroglucinol model system. When the optimised ATPS system was tested with a polyphenol extract, 93.62±8.24% recovery was observed. When ATPS was applied to a fucoidan and alginate biorefinery residue, 88.40±4.59% polyphenol was recovered. These findings confirm that ATPS is a valuable addition to the bioprocess toolkit for sustainable extraction of natural products from macroalgae in a multiproduct biorefinery approach. Practical application Selection of the best concentrations of phase-forming components and recovery conditions for the application of aqueous two-phase systems in an industrial setup has been proved to be laborious and cumbersome. This paper presents an automated platform to rapidly assess several ATPS to recover polyphenols from brown macroalgae and a subsequent confirmation with the scale-up of the potential candidates and contrasted with two case studies. This methodology allows a quick screening for the best aqueous two-phase system and can be expanded to recover high-value products from other types of macroalgae or microalgae." @default.
- W3176937323 created "2021-07-05" @default.
- W3176937323 creator A5034870647 @default.
- W3176937323 creator A5069835557 @default.
- W3176937323 date "2021-06-30" @default.
- W3176937323 modified "2023-09-26" @default.
- W3176937323 title "High-throughput screening of aqueous two-phase systems for polyphenol extraction from<i>A. nodosum</i>: a green chemistry approach" @default.
- W3176937323 cites W1023230292 @default.
- W3176937323 cites W1546823599 @default.
- W3176937323 cites W1971627486 @default.
- W3176937323 cites W1976905320 @default.
- W3176937323 cites W1978174543 @default.
- W3176937323 cites W1987594571 @default.
- W3176937323 cites W2001896961 @default.
- W3176937323 cites W2015182930 @default.
- W3176937323 cites W2019934106 @default.
- W3176937323 cites W2020704631 @default.
- W3176937323 cites W2022072246 @default.
- W3176937323 cites W2039407469 @default.
- W3176937323 cites W2083424845 @default.
- W3176937323 cites W2094339639 @default.
- W3176937323 cites W2099775707 @default.
- W3176937323 cites W2108581257 @default.
- W3176937323 cites W2119866485 @default.
- W3176937323 cites W2129178711 @default.
- W3176937323 cites W2338153244 @default.
- W3176937323 cites W2401374364 @default.
- W3176937323 cites W2493206281 @default.
- W3176937323 cites W2550202979 @default.
- W3176937323 cites W2769823983 @default.
- W3176937323 cites W2795062853 @default.
- W3176937323 cites W2884925149 @default.
- W3176937323 cites W2912175280 @default.
- W3176937323 cites W2916514573 @default.
- W3176937323 cites W2936044891 @default.
- W3176937323 cites W2991775584 @default.
- W3176937323 doi "https://doi.org/10.1101/2021.06.28.450208" @default.
- W3176937323 hasPublicationYear "2021" @default.
- W3176937323 type Work @default.
- W3176937323 sameAs 3176937323 @default.
- W3176937323 citedByCount "0" @default.
- W3176937323 crossrefType "posted-content" @default.
- W3176937323 hasAuthorship W3176937323A5034870647 @default.
- W3176937323 hasAuthorship W3176937323A5069835557 @default.
- W3176937323 hasBestOaLocation W31769373231 @default.
- W3176937323 hasConcept C149556010 @default.
- W3176937323 hasConcept C178790620 @default.
- W3176937323 hasConcept C184651966 @default.
- W3176937323 hasConcept C185592680 @default.
- W3176937323 hasConcept C206139338 @default.
- W3176937323 hasConcept C2778004101 @default.
- W3176937323 hasConcept C2778626014 @default.
- W3176937323 hasConcept C2779216985 @default.
- W3176937323 hasConcept C2780301381 @default.
- W3176937323 hasConcept C43617362 @default.
- W3176937323 hasConcept C4725764 @default.
- W3176937323 hasConcept C559758991 @default.
- W3176937323 hasConcept C59822182 @default.
- W3176937323 hasConcept C70899900 @default.
- W3176937323 hasConcept C86803240 @default.
- W3176937323 hasConceptScore W3176937323C149556010 @default.
- W3176937323 hasConceptScore W3176937323C178790620 @default.
- W3176937323 hasConceptScore W3176937323C184651966 @default.
- W3176937323 hasConceptScore W3176937323C185592680 @default.
- W3176937323 hasConceptScore W3176937323C206139338 @default.
- W3176937323 hasConceptScore W3176937323C2778004101 @default.
- W3176937323 hasConceptScore W3176937323C2778626014 @default.
- W3176937323 hasConceptScore W3176937323C2779216985 @default.
- W3176937323 hasConceptScore W3176937323C2780301381 @default.
- W3176937323 hasConceptScore W3176937323C43617362 @default.
- W3176937323 hasConceptScore W3176937323C4725764 @default.
- W3176937323 hasConceptScore W3176937323C559758991 @default.
- W3176937323 hasConceptScore W3176937323C59822182 @default.
- W3176937323 hasConceptScore W3176937323C70899900 @default.
- W3176937323 hasConceptScore W3176937323C86803240 @default.
- W3176937323 hasLocation W31769373231 @default.
- W3176937323 hasOpenAccess W3176937323 @default.
- W3176937323 hasPrimaryLocation W31769373231 @default.
- W3176937323 hasRelatedWork W1987997155 @default.
- W3176937323 hasRelatedWork W2054456172 @default.
- W3176937323 hasRelatedWork W2347427010 @default.
- W3176937323 hasRelatedWork W2368175654 @default.
- W3176937323 hasRelatedWork W2374139875 @default.
- W3176937323 hasRelatedWork W2376795259 @default.
- W3176937323 hasRelatedWork W2383205745 @default.
- W3176937323 hasRelatedWork W2387182253 @default.
- W3176937323 hasRelatedWork W3176937323 @default.
- W3176937323 hasRelatedWork W318577875 @default.
- W3176937323 isParatext "false" @default.
- W3176937323 isRetracted "false" @default.
- W3176937323 magId "3176937323" @default.
- W3176937323 workType "article" @default.