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- W3177252003 abstract "Objective: To evaluate the effect of herbal syrup Linkus on acute and gross toxicity and electrolytes level in blood and organs.Materials and Methods: This interventional study was carried out in the department of Pharmacology, Faculty ofPharmacy,University of Karachi after approval from BASR-KU. In this study twenty-eight healthy rabbits of either sex weighing0.90 kg to 1.2 kg. All animals were equally divided into four groups, one served as control group while, remaining three groupsreceived herbal syrup Linkus at three different doses. Acute toxicity was tested in mice by Lorke’s method whereas effect ongross toxicity, blood and organ electrolytes was evaluated in Rabbits.Results: Herbal syrup Linkus exhibited LD50 values greater than 5 gm / kg per 24 hrs. No gross toxicity and mortality wasobserved during the whole experimental period. Non significant changes were observed in blood and organ electrolytes (Calcium,Potassium and Sodium) level.Conclusion: Herbal syrup Linkus has produced no toxic effect at the administered doses neither showed any significant changein the electrolytes level in the blood and vital organs." @default.
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- W3177252003 date "2016-09-14" @default.
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- W3177252003 title "Effect of Herbal Syrup Linkus on Acute and Gross Toxicity and Electrolytes in Blood and Organs" @default.
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