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- W3177283821 endingPage "107942" @default.
- W3177283821 startingPage "107942" @default.
- W3177283821 abstract "Vitamin A is an important micro-essential nutrient, whose primary dietary source is retinyl esters. In addition, β-carotene (pro-vitamin A) is a precursor of vitamin A contained in green and yellow vegetables that is converted to retinol in the body after ingestion. Retinol is oxidized to produce visual retinal, which is further oxidized to retinoic acid (RA), which is used as a therapeutic agent for patients with promyelocytic leukemia. Thus, the effects of retinal and RA are well known. In this paper, we will introduce (1) vitamin A circulation in the body, (2) the actions and mechanisms of retinal and RA, (3) retinoylation: another RA mechanism not depending on RA receptors, (4) the relationship between cancer and actions of retinol or β-carotene, whose roles in vivo are still unknown, and (5) anti-cancer actions of vitamin A derivatives derived from fenretinide (4-HPR). We propose that vitamin A nutritional management is effective in the prevention of cancer." @default.
- W3177283821 created "2021-07-05" @default.
- W3177283821 creator A5035038653 @default.
- W3177283821 creator A5041858131 @default.
- W3177283821 creator A5066555365 @default.
- W3177283821 creator A5072628472 @default.
- W3177283821 creator A5076993537 @default.
- W3177283821 date "2022-02-01" @default.
- W3177283821 modified "2023-10-14" @default.
- W3177283821 title "Vitamin A in health care: Suppression of growth and induction of differentiation in cancer cells by vitamin A and its derivatives and their mechanisms of action" @default.
- W3177283821 cites W1491275120 @default.
- W3177283821 cites W1506613684 @default.
- W3177283821 cites W1511319187 @default.
- W3177283821 cites W1568523187 @default.
- W3177283821 cites W1578462325 @default.
- W3177283821 cites W1817269218 @default.
- W3177283821 cites W1963781577 @default.
- W3177283821 cites W1965089781 @default.
- W3177283821 cites W1966580060 @default.
- W3177283821 cites W1968737946 @default.
- W3177283821 cites W1973978837 @default.
- W3177283821 cites W1974630525 @default.
- W3177283821 cites W1977575430 @default.
- W3177283821 cites W1978959501 @default.
- W3177283821 cites W1985766599 @default.
- W3177283821 cites W1987269203 @default.
- W3177283821 cites W1989349753 @default.
- W3177283821 cites W1993404189 @default.
- W3177283821 cites W1995240135 @default.
- W3177283821 cites W1996388358 @default.
- W3177283821 cites W1996709797 @default.
- W3177283821 cites W1999499889 @default.
- W3177283821 cites W2000502515 @default.
- W3177283821 cites W2001543903 @default.
- W3177283821 cites W2003289032 @default.
- W3177283821 cites W2006782328 @default.
- W3177283821 cites W2007880981 @default.
- W3177283821 cites W2008021517 @default.
- W3177283821 cites W2008245372 @default.
- W3177283821 cites W2011013686 @default.
- W3177283821 cites W2012428888 @default.
- W3177283821 cites W2016392505 @default.
- W3177283821 cites W2018320862 @default.
- W3177283821 cites W2018604337 @default.
- W3177283821 cites W2024374906 @default.
- W3177283821 cites W2031403549 @default.
- W3177283821 cites W2031637049 @default.
- W3177283821 cites W2039278660 @default.
- W3177283821 cites W2041207464 @default.
- W3177283821 cites W2041406318 @default.
- W3177283821 cites W2042031496 @default.
- W3177283821 cites W2043211160 @default.
- W3177283821 cites W2043874513 @default.
- W3177283821 cites W2046594970 @default.
- W3177283821 cites W2047508855 @default.
- W3177283821 cites W2049791242 @default.
- W3177283821 cites W2051529158 @default.
- W3177283821 cites W2060025378 @default.
- W3177283821 cites W2067821847 @default.
- W3177283821 cites W2068740421 @default.
- W3177283821 cites W2070247033 @default.
- W3177283821 cites W2072233737 @default.
- W3177283821 cites W2072754115 @default.
- W3177283821 cites W2072822958 @default.
- W3177283821 cites W2073445444 @default.
- W3177283821 cites W2075755158 @default.
- W3177283821 cites W2076771507 @default.
- W3177283821 cites W2078610083 @default.
- W3177283821 cites W2085069569 @default.
- W3177283821 cites W2085116251 @default.
- W3177283821 cites W2085538566 @default.
- W3177283821 cites W2089070253 @default.
- W3177283821 cites W2092986999 @default.
- W3177283821 cites W2093947533 @default.
- W3177283821 cites W2098860085 @default.
- W3177283821 cites W2101744160 @default.
- W3177283821 cites W2116394959 @default.
- W3177283821 cites W2118363290 @default.
- W3177283821 cites W2122844011 @default.
- W3177283821 cites W2125429880 @default.
- W3177283821 cites W2129105333 @default.
- W3177283821 cites W2129387993 @default.
- W3177283821 cites W2132335701 @default.
- W3177283821 cites W2134277793 @default.
- W3177283821 cites W2139201146 @default.
- W3177283821 cites W2141083396 @default.
- W3177283821 cites W2167484695 @default.
- W3177283821 cites W2167599338 @default.
- W3177283821 cites W2171322600 @default.
- W3177283821 cites W2182224080 @default.
- W3177283821 cites W2184107901 @default.
- W3177283821 cites W2265494186 @default.
- W3177283821 cites W2270628737 @default.
- W3177283821 cites W2278583156 @default.
- W3177283821 cites W2292078482 @default.
- W3177283821 cites W2317242858 @default.
- W3177283821 cites W2412227126 @default.
- W3177283821 cites W2468222881 @default.