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• W3177635523 abstract "We herein report an efficient approach for the assembly of multiply substituted imidazoles and oxazoles in a single-step manner. These transformations are based on a decarboxylation addition and annulation of readily accessible aromatic carboxylic acids and aliphatic nitriles and exhibit good functional group compatibility and a high step economy. The reaction is scalable, and as-prepared products could be transformed into practical skeletons. Importantly, the late-stage derivatization of Momelotinib highlights the potential utility of this methodology." @default.
• W3177635523 created "2021-07-19" @default.
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• W3177635523 date "2021-07-12" @default.
• W3177635523 modified "2023-10-10" @default.
• W3177635523 title "Synthesis of Imidazoles and Oxazoles via a Palladium-Catalyzed Decarboxylative Addition/Cyclization Reaction Sequence of Aromatic Carboxylic Acids with Functionalized Aliphatic Nitriles" @default.
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• W3177635523 doi "https://doi.org/10.1021/acs.orglett.1c01762" @default.
• W3177635523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34251821" @default.
• W3177635523 hasPublicationYear "2021" @default.
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