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• W3178173005 abstract "Subacute sclerosing panencephalitis (SSPE) is a slow virus infection associated with mutant measles virus (MeV). The long-term outcome of antiviral treatments remains to be determined. We herein present a Japanese boy who was diagnosed with SSPE at 10 years of age. Intraventricular infusions of interferon-α effectively prevented the progress of symptoms during 14 years of follow-up period. Flow-cytometric analysis demonstrated higher proportion of T helper 17 cells (Th17, 18.2%) than healthy controls (4.8-14.5%) despite the normal subpopulation of peripheral lymphocytes. These data suggest that a group of patients with SSPE may show favorable responses to intraventricular infusions of interferon-α." @default.
• W3178173005 created "2021-07-19" @default.
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• W3178173005 date "2021-09-01" @default.
• W3178173005 modified "2023-10-18" @default.
• W3178173005 title "Favorable outcomes of interferon-α and ribavirin treatment for a male with subacute sclerosing panencephalitis" @default.
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• W3178173005 doi "https://doi.org/10.1016/j.jneuroim.2021.577656" @default.
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