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- W3178177545 abstract "TrombotickĂŠ komplikace u nemocnĂ˝ch s covid-19 postihujĂ cĂŠvy plic, konÄetin, sleziny, srdce, mozku a/nebo ledvin (1). Tyto komplikace jsou obvykle spojeny s multiorgĂĄnovĂ˝m selhĂĄnĂm a vysokou mortalitou. PlicnĂ embolie a hlubokĂĄ ĹžilnĂ trombĂłza jsou nejÄastÄjĹĄĂ trombotickĂŠ pĹĂhody u covid-19 (1). Riziko venĂłznĂ tromboembolie zĹŻstĂĄvĂĄ vysokĂŠ u hospitalizovanĂ˝ch pacientĹŻ navzdory antikoagulaÄnĂ profylaxi. Cytokiny, proteinovĂŠ prozĂĄnÄtlivĂŠ mediĂĄtory, slouĹžĂcĂ jako klĂÄovĂĄ signalizaÄnĂ cesta, jsou zodpovÄdnĂŠ za posun endoteliĂĄlnĂ funkce z homeostatickĂŠ do obrannĂŠho reĹžimu. KritickĂŠ stadium covid-19 obvykle zahrnuje cytokinovou bouĹi, jiĹž dĹĂve dobĹe popsanou pozitivnĂ zpÄtnou vazbu, kterĂĄ ĹĂdĂ produkci cytokinĹŻ a zahlcuje protiregulaÄnĂ mechanismy." @default.
- W3178177545 created "2021-07-19" @default.
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- W3178177545 date "2021-07-09" @default.
- W3178177545 modified "2023-09-27" @default.
- W3178177545 title "Thrombotic complications of covid-19: a brief review of current opinions" @default.
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- W3178177545 doi "https://doi.org/10.36290/kar.2021.028" @default.
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