FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3178352178> ?p ?o ?g. }

• W3178352178 endingPage "2927" @default.
• W3178352178 startingPage "2919" @default.
• W3178352178 abstract "Abstract The widespread apicomplexan parasite Cryptosporidium parvum is responsible for severe gastrointestinal disease in humans and animals. The treatment options are limited, and the efficacy of available drugs is low. Bark contains condensed tannins (CT), which are bioactive compounds previously shown to inhibit parasite development. Here, we examined the anti-cryptosporidial properties of bark extract of Scots pine ( Pinus sylvestris ) against C. parvum by means of an in vitro growth inhibition test. We hypothesised that bark extracts would have dose-dependent inhibitory effects on the development of C. parvum in cell culture. Bark extracts from Scots pine extracted with acetone, methanol, and water as solvents were investigated using human colorectal adenocarcinoma cells infected with C. parvum . Oocysts were inoculated onto the cell monolayer and bark extract was added at seven different concentrations. Parasite growth inhibition was quantified by qPCR. The acetone and methanol extracts demonstrated a sigmoid dose-dependent inhibition of C. parvum . The IC 50 values were 244.6 and 279.1 µg dry matter extract/mL, and 25.4 and 24.1 µg CT/mL, for acetone and methanol extracts, respectively. The IC 50 for both extracts were similar, both with regard to the dry matter concentration of each extract and to CT concentrations. Given the limited treatment options available for Cryptosporidium spp., the evidence generated in our study encourages further investigation into the in vitro and in vivo effects of pine bark extracts against C. parvum." @default.
• W3178352178 created "2021-07-19" @default.
• W3178352178 creator A5001374639 @default.
• W3178352178 creator A5009156713 @default.
• W3178352178 creator A5030566645 @default.
• W3178352178 creator A5051590890 @default.
• W3178352178 creator A5053167122 @default.
• W3178352178 creator A5061315980 @default.
• W3178352178 creator A5062561634 @default.
• W3178352178 creator A5070464166 @default.
• W3178352178 creator A5075094906 @default.
• W3178352178 creator A5089548630 @default.
• W3178352178 date "2021-07-16" @default.
• W3178352178 modified "2023-10-15" @default.
• W3178352178 title "Extracts of pine bark (Pinus sylvestris) inhibit Cryptosporidium parvum growth in cell culture" @default.
• W3178352178 cites W1480087692 @default.
• W3178352178 cites W1701869895 @default.
• W3178352178 cites W1965414378 @default.
• W3178352178 cites W1986049212 @default.
• W3178352178 cites W1989559657 @default.
• W3178352178 cites W2019981703 @default.
• W3178352178 cites W2020984386 @default.
• W3178352178 cites W2023472969 @default.
• W3178352178 cites W2025457591 @default.
• W3178352178 cites W2027933530 @default.
• W3178352178 cites W2034758586 @default.
• W3178352178 cites W2039134806 @default.
• W3178352178 cites W2043110699 @default.
• W3178352178 cites W2043736013 @default.
• W3178352178 cites W2044887247 @default.
• W3178352178 cites W2049472963 @default.
• W3178352178 cites W2062165684 @default.
• W3178352178 cites W2078187063 @default.
• W3178352178 cites W2079094059 @default.
• W3178352178 cites W2099912429 @default.
• W3178352178 cites W2108870664 @default.
• W3178352178 cites W2112114783 @default.
• W3178352178 cites W2123501127 @default.
• W3178352178 cites W2124706578 @default.
• W3178352178 cites W2131240655 @default.
• W3178352178 cites W2133569001 @default.
• W3178352178 cites W2135874336 @default.
• W3178352178 cites W2148048407 @default.
• W3178352178 cites W2148424723 @default.
• W3178352178 cites W2168420558 @default.
• W3178352178 cites W2275412384 @default.
• W3178352178 cites W2329810664 @default.
• W3178352178 cites W2410982588 @default.
• W3178352178 cites W2520679523 @default.
• W3178352178 cites W2606661145 @default.
• W3178352178 cites W2609262167 @default.
• W3178352178 cites W2765162212 @default.
• W3178352178 cites W2768616041 @default.
• W3178352178 cites W2769006680 @default.
• W3178352178 cites W2770567553 @default.
• W3178352178 cites W2789744874 @default.
• W3178352178 cites W2897670792 @default.
• W3178352178 cites W2907134212 @default.
• W3178352178 cites W2909469648 @default.
• W3178352178 cites W2960635232 @default.
• W3178352178 cites W2995914391 @default.
• W3178352178 cites W2998538017 @default.
• W3178352178 cites W3002846308 @default.
• W3178352178 cites W79161117 @default.
• W3178352178 cites W809603292 @default.
• W3178352178 doi "https://doi.org/10.1007/s00436-021-07220-w" @default.
• W3178352178 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8370916" @default.
• W3178352178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34269871" @default.
• W3178352178 hasPublicationYear "2021" @default.
• W3178352178 type Work @default.
• W3178352178 sameAs 3178352178 @default.
• W3178352178 citedByCount "6" @default.
• W3178352178 countsByYear W31783521782022 @default.
• W3178352178 countsByYear W31783521782023 @default.
• W3178352178 crossrefType "journal-article" @default.
• W3178352178 hasAuthorship W3178352178A5001374639 @default.
• W3178352178 hasAuthorship W3178352178A5009156713 @default.
• W3178352178 hasAuthorship W3178352178A5030566645 @default.
• W3178352178 hasAuthorship W3178352178A5051590890 @default.
• W3178352178 hasAuthorship W3178352178A5053167122 @default.
• W3178352178 hasAuthorship W3178352178A5061315980 @default.
• W3178352178 hasAuthorship W3178352178A5062561634 @default.
• W3178352178 hasAuthorship W3178352178A5070464166 @default.
• W3178352178 hasAuthorship W3178352178A5075094906 @default.
• W3178352178 hasAuthorship W3178352178A5089548630 @default.
• W3178352178 hasBestOaLocation W31783521781 @default.
• W3178352178 hasConcept C133446333 @default.
• W3178352178 hasConcept C136764020 @default.
• W3178352178 hasConcept C150903083 @default.
• W3178352178 hasConcept C18903297 @default.
• W3178352178 hasConcept C202751555 @default.
• W3178352178 hasConcept C207001950 @default.
• W3178352178 hasConcept C2777795018 @default.
• W3178352178 hasConcept C2779128174 @default.
• W3178352178 hasConcept C2781213060 @default.
• W3178352178 hasConcept C2910048773 @default.
• W3178352178 hasConcept C41008148 @default.
• W3178352178 hasConcept C55493867 @default.

• next