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• W3178655959 endingPage "102449" @default.
• W3178655959 startingPage "102449" @default.
• W3178655959 abstract "Anxiety disorders (ADs) are common and difficult to treat. While research suggests ADs are characterized by an imbalance between bottom-up and top-down attention processes and that effective treatments work by correcting this dysfunction, there is insufficient data to explain how and for whom treatments work. The late positive potential (LPP), an event-related potential reflecting elaborative processing of motivationally salient stimuli, is sensitive to both bottom-up and top-down processes. The present study examines the LPP in healthy controls (HC) and patients with ADs under low and high working memory (WM) load to assess its utility as a predictor and index of symptom reduction in patients who underwent cognitive behavioral therapy (CBT) or selective serotonin reuptake inhibitor (SSRI) treatment. The LPP when viewing negative and neutral distractor images and WM performance were assessed in 96 participants (40 HC, 32 CBT, 24 SSRI) during a letter recall task at Week 0 and in a subset of the study sample (23 CBT, 16 SSRI) at Week 12. Patients were randomly assigned to twelve weeks of CBT or SSRI treatment. Participants completed self-reported symptom measures at each time point. Greater Week 0 LPP to negative images under low WM load predicted greater symptom reduction in the SSRI, but not the CBT, group. Regression analyses examining the LPP to negative images as an index of symptom reduction revealed a smaller decrease in the LPP to negative images under low WM load was associated with less anxiety reduction across treatment modalities. Findings suggest the LPP during low WM load may serve as a cost-effective predictor and index of treatment outcome in ADs. Clinical Trials Registration: ClinicalTrials.gov (Identifier: NCT01903447)." @default.
• W3178655959 created "2021-07-19" @default.
• W3178655959 creator A5006013455 @default.
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• W3178655959 creator A5076242269 @default.
• W3178655959 date "2021-08-01" @default.
• W3178655959 modified "2023-10-16" @default.
• W3178655959 title "Neural mechanisms and predictors of SSRI and CBT treatment of anxiety: A randomized trial focused on emotion and cognitive processing" @default.
• W3178655959 cites W1160212399 @default.
• W3178655959 cites W1526231820 @default.
• W3178655959 cites W1608074949 @default.
• W3178655959 cites W1916891444 @default.
• W3178655959 cites W1970443848 @default.
• W3178655959 cites W1977465442 @default.
• W3178655959 cites W1988612597 @default.
• W3178655959 cites W1989756802 @default.
• W3178655959 cites W1992103170 @default.
• W3178655959 cites W1993400322 @default.
• W3178655959 cites W1996860933 @default.
• W3178655959 cites W1998455072 @default.
• W3178655959 cites W2009414417 @default.
• W3178655959 cites W2009819148 @default.
• W3178655959 cites W2013876942 @default.
• W3178655959 cites W2017388263 @default.
• W3178655959 cites W2022288443 @default.
• W3178655959 cites W2035314636 @default.
• W3178655959 cites W2036191824 @default.
• W3178655959 cites W2051929926 @default.
• W3178655959 cites W2052478013 @default.
• W3178655959 cites W2053445456 @default.
• W3178655959 cites W2053944890 @default.
• W3178655959 cites W2056417333 @default.
• W3178655959 cites W2063619953 @default.
• W3178655959 cites W2068297463 @default.
• W3178655959 cites W2068550908 @default.
• W3178655959 cites W2068910921 @default.
• W3178655959 cites W2086683169 @default.
• W3178655959 cites W2096208065 @default.
• W3178655959 cites W2097686780 @default.
• W3178655959 cites W2100541875 @default.
• W3178655959 cites W2101024643 @default.
• W3178655959 cites W2104699321 @default.
• W3178655959 cites W2106345317 @default.
• W3178655959 cites W2106654511 @default.
• W3178655959 cites W2107540720 @default.
• W3178655959 cites W2114512489 @default.
• W3178655959 cites W2118826874 @default.
• W3178655959 cites W2121363268 @default.
• W3178655959 cites W2131614450 @default.
• W3178655959 cites W2134534003 @default.
• W3178655959 cites W2140110954 @default.
• W3178655959 cites W2143114368 @default.
• W3178655959 cites W2145220156 @default.
• W3178655959 cites W2147996559 @default.
• W3178655959 cites W2149139854 @default.
• W3178655959 cites W2151490465 @default.
• W3178655959 cites W2154201624 @default.
• W3178655959 cites W2166523051 @default.
• W3178655959 cites W2170184275 @default.
• W3178655959 cites W2187770635 @default.
• W3178655959 cites W2203700218 @default.
• W3178655959 cites W2293089587 @default.
• W3178655959 cites W2323660729 @default.
• W3178655959 cites W2343366531 @default.
• W3178655959 cites W2404163590 @default.
• W3178655959 cites W2415743048 @default.
• W3178655959 cites W2430856946 @default.
• W3178655959 cites W2515097486 @default.
• W3178655959 cites W2522867222 @default.
• W3178655959 cites W2532017239 @default.
• W3178655959 cites W2577085700 @default.
• W3178655959 cites W2610347929 @default.
• W3178655959 cites W2795248087 @default.
• W3178655959 cites W2802863487 @default.
• W3178655959 cites W2913684934 @default.
• W3178655959 cites W2926876025 @default.
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• W3178655959 cites W2973387616 @default.
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• W3178655959 doi "https://doi.org/10.1016/j.janxdis.2021.102449" @default.
• W3178655959 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8364887" @default.
• W3178655959 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34274600" @default.
• W3178655959 hasPublicationYear "2021" @default.
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