FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3178844218> ?p ?o ?g. }

• W3178844218 endingPage "073047" @default.
• W3178844218 startingPage "073047" @default.
• W3178844218 abstract "Human brain tissue is a heterogeneous material, consisting of soft outer grey matter tethered internally by stiffer cords of white matter. These white matter tracts conduct electrical impulses between grey matter regions, thereby underpinning neuronal communication. Understanding the material properties of white matter is thus crucial for understanding brain function generally. Efforts to assess white matter microstructure are currently hampered by the inherent limitations of reconstruction by diffusion imaging. Techniques typically represent white matter structures with single scalars that are often difficult to interpret. Here, we address these issues by introducing tools from materials physics for the characterization of white matter microstructure. We investigate structure on a mesoscopic scale by analyzing its homogeneity and determining which regions of the brain are structurally homogeneous, or ``crystalline in the context of materials physics. We find that crystallinity provides novel information and varies across the brain along interpretable lines of anatomical difference, with highest homogeneity in regions adjacent to the corpus callosum, a large interhemispheric tract. Furthermore, crystallinity is markedly reliable across iterative measurement, yet also varies between individual human volunteers, making it potentially useful for examining individual differences in white matter along several dimensions including sex and age. We also parcellate white matter into ``crystal grains, or contiguous sets of voxels of high structural similarity, and find overlap with a common atlas of distinct white matter areas. Finally, we characterize the shapes of individual diffusion signatures through another tool from materials physics --bond-orientational order parameters-- to locate fiber crossings and fascicles. Our results provide new means of assessing white matter microstructure on multiple length scales, and open multiple avenues of future inquiry involving soft matter physics and neuroscience." @default.
• W3178844218 created "2021-07-19" @default.
• W3178844218 creator A5009266404 @default.
• W3178844218 creator A5039906500 @default.
• W3178844218 creator A5052291232 @default.
• W3178844218 creator A5058453821 @default.
• W3178844218 creator A5062840830 @default.
• W3178844218 creator A5082140726 @default.
• W3178844218 creator A5085933261 @default.
• W3178844218 date "2021-07-01" @default.
• W3178844218 modified "2023-10-03" @default.
• W3178844218 title "Crystallinity characterization of white matter in the human brain" @default.
• W3178844218 cites W1197925356 @default.
• W3178844218 cites W1529598366 @default.
• W3178844218 cites W1672229930 @default.
• W3178844218 cites W1946498797 @default.
• W3178844218 cites W1968135525 @default.
• W3178844218 cites W1968285450 @default.
• W3178844218 cites W1970928383 @default.
• W3178844218 cites W1981734795 @default.
• W3178844218 cites W1985385518 @default.
• W3178844218 cites W1988954604 @default.
• W3178844218 cites W2001611992 @default.
• W3178844218 cites W2009202887 @default.
• W3178844218 cites W2011815991 @default.
• W3178844218 cites W2012849219 @default.
• W3178844218 cites W2019307288 @default.
• W3178844218 cites W2020306690 @default.
• W3178844218 cites W2022244667 @default.
• W3178844218 cites W2027102257 @default.
• W3178844218 cites W2029888243 @default.
• W3178844218 cites W2031612583 @default.
• W3178844218 cites W2039162483 @default.
• W3178844218 cites W2044345351 @default.
• W3178844218 cites W2046132588 @default.
• W3178844218 cites W2055342187 @default.
• W3178844218 cites W2060633636 @default.
• W3178844218 cites W2061099285 @default.
• W3178844218 cites W2061708164 @default.
• W3178844218 cites W2062791478 @default.
• W3178844218 cites W2067724039 @default.
• W3178844218 cites W2070292918 @default.
• W3178844218 cites W2077818116 @default.
• W3178844218 cites W2078989713 @default.
• W3178844218 cites W2084855057 @default.
• W3178844218 cites W2085394612 @default.
• W3178844218 cites W2089367740 @default.
• W3178844218 cites W2092122022 @default.
• W3178844218 cites W2092204065 @default.
• W3178844218 cites W2095293504 @default.
• W3178844218 cites W2098644398 @default.
• W3178844218 cites W2104598584 @default.
• W3178844218 cites W2106841463 @default.
• W3178844218 cites W2107622759 @default.
• W3178844218 cites W2111090475 @default.
• W3178844218 cites W2112037540 @default.
• W3178844218 cites W2113366456 @default.
• W3178844218 cites W2117024762 @default.
• W3178844218 cites W2117311229 @default.
• W3178844218 cites W2117987496 @default.
• W3178844218 cites W2122410839 @default.
• W3178844218 cites W2123101350 @default.
• W3178844218 cites W2127048411 @default.
• W3178844218 cites W2129461335 @default.
• W3178844218 cites W2130142990 @default.
• W3178844218 cites W2136489734 @default.
• W3178844218 cites W2141161838 @default.
• W3178844218 cites W2141403362 @default.
• W3178844218 cites W2148828979 @default.
• W3178844218 cites W2151712416 @default.
• W3178844218 cites W2156893545 @default.
• W3178844218 cites W2157035009 @default.
• W3178844218 cites W2158123498 @default.
• W3178844218 cites W2159210265 @default.
• W3178844218 cites W2160215963 @default.
• W3178844218 cites W2160960948 @default.
• W3178844218 cites W2161119653 @default.
• W3178844218 cites W2170328207 @default.
• W3178844218 cites W2275837766 @default.
• W3178844218 cites W2321627145 @default.
• W3178844218 cites W2492785636 @default.
• W3178844218 cites W2499800833 @default.
• W3178844218 cites W2508982726 @default.
• W3178844218 cites W2520744072 @default.
• W3178844218 cites W2522628945 @default.
• W3178844218 cites W2588543849 @default.
• W3178844218 cites W2626719974 @default.
• W3178844218 cites W2785401337 @default.
• W3178844218 cites W2785925704 @default.
• W3178844218 cites W2805432993 @default.
• W3178844218 cites W2886105060 @default.
• W3178844218 cites W2951943166 @default.
• W3178844218 cites W2953259383 @default.
• W3178844218 cites W2963156478 @default.
• W3178844218 cites W2963622774 @default.
• W3178844218 cites W2964986786 @default.
• W3178844218 cites W2970244213 @default.
• W3178844218 cites W2989787606 @default.

• next