FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3178994804> ?p ?o ?g. }

• W3178994804 abstract "Malaria patients can carry one or more clonal lineage of the parasite, Plasmodium falciparum. Well-defined, complete haplotypes at single-cell resolution are ideal for describing within-host population structure and unambiguously determining parasite diversity, transmission dynamics and recent ancestry but have not been analyzed on a large scale. We generated 485 near-complete single-cell genome sequences isolated from fifteen P. falciparum patients from Chikhwawa, Malawi, an area of intense malaria transmission. Matched single-cell and bulk genomic analyses revealed patients harbored up to seventeen unique lineages. Current statistical approaches were unable to accurately reconstruct infection composition from bulk sequence data. Analysis of parasite relatedness within patients suggests superinfection by repeated mosquito bites is rarer than co-transmission of parasites from a single mosquito. Our single-cell analysis indicates strong barriers to establishment of secondary infections, providing new insights into the biology and transmission of malaria." @default.
• W3178994804 created "2021-07-19" @default.
• W3178994804 creator A5001319442 @default.
• W3178994804 creator A5006891244 @default.
• W3178994804 creator A5008177587 @default.
• W3178994804 creator A5008381642 @default.
• W3178994804 creator A5017446368 @default.
• W3178994804 creator A5021621374 @default.
• W3178994804 creator A5022298202 @default.
• W3178994804 creator A5027720964 @default.
• W3178994804 creator A5031747090 @default.
• W3178994804 creator A5043733275 @default.
• W3178994804 creator A5060849361 @default.
• W3178994804 creator A5061493364 @default.
• W3178994804 creator A5070886904 @default.
• W3178994804 date "2018-01-01" @default.
• W3178994804 modified "2023-09-27" @default.
• W3178994804 title "Single Cell Genomic Dissection of Complex African Malaria Infections Suggest Strong Barriers to Reinfection" @default.
• W3178994804 doi "https://doi.org/10.2139/ssrn.3283705" @default.
• W3178994804 hasPublicationYear "2018" @default.
• W3178994804 type Work @default.
• W3178994804 sameAs 3178994804 @default.
• W3178994804 citedByCount "0" @default.
• W3178994804 crossrefType "journal-article" @default.
• W3178994804 hasAuthorship W3178994804A5001319442 @default.
• W3178994804 hasAuthorship W3178994804A5006891244 @default.
• W3178994804 hasAuthorship W3178994804A5008177587 @default.
• W3178994804 hasAuthorship W3178994804A5008381642 @default.
• W3178994804 hasAuthorship W3178994804A5017446368 @default.
• W3178994804 hasAuthorship W3178994804A5021621374 @default.
• W3178994804 hasAuthorship W3178994804A5022298202 @default.
• W3178994804 hasAuthorship W3178994804A5027720964 @default.
• W3178994804 hasAuthorship W3178994804A5031747090 @default.
• W3178994804 hasAuthorship W3178994804A5043733275 @default.
• W3178994804 hasAuthorship W3178994804A5060849361 @default.
• W3178994804 hasAuthorship W3178994804A5061493364 @default.
• W3178994804 hasAuthorship W3178994804A5070886904 @default.
• W3178994804 hasConcept C104317684 @default.
• W3178994804 hasConcept C119599485 @default.
• W3178994804 hasConcept C127413603 @default.
• W3178994804 hasConcept C135763542 @default.
• W3178994804 hasConcept C136764020 @default.
• W3178994804 hasConcept C141231307 @default.
• W3178994804 hasConcept C159047783 @default.
• W3178994804 hasConcept C197754878 @default.
• W3178994804 hasConcept C203014093 @default.
• W3178994804 hasConcept C2522874641 @default.
• W3178994804 hasConcept C2776817793 @default.
• W3178994804 hasConcept C2778048844 @default.
• W3178994804 hasConcept C2778371730 @default.
• W3178994804 hasConcept C2778675580 @default.
• W3178994804 hasConcept C2779617845 @default.
• W3178994804 hasConcept C2908647359 @default.
• W3178994804 hasConcept C41008148 @default.
• W3178994804 hasConcept C54355233 @default.
• W3178994804 hasConcept C71924100 @default.
• W3178994804 hasConcept C71928629 @default.
• W3178994804 hasConcept C761482 @default.
• W3178994804 hasConcept C78458016 @default.
• W3178994804 hasConcept C86803240 @default.
• W3178994804 hasConcept C99454951 @default.
• W3178994804 hasConceptScore W3178994804C104317684 @default.
• W3178994804 hasConceptScore W3178994804C119599485 @default.
• W3178994804 hasConceptScore W3178994804C127413603 @default.
• W3178994804 hasConceptScore W3178994804C135763542 @default.
• W3178994804 hasConceptScore W3178994804C136764020 @default.
• W3178994804 hasConceptScore W3178994804C141231307 @default.
• W3178994804 hasConceptScore W3178994804C159047783 @default.
• W3178994804 hasConceptScore W3178994804C197754878 @default.
• W3178994804 hasConceptScore W3178994804C203014093 @default.
• W3178994804 hasConceptScore W3178994804C2522874641 @default.
• W3178994804 hasConceptScore W3178994804C2776817793 @default.
• W3178994804 hasConceptScore W3178994804C2778048844 @default.
• W3178994804 hasConceptScore W3178994804C2778371730 @default.
• W3178994804 hasConceptScore W3178994804C2778675580 @default.
• W3178994804 hasConceptScore W3178994804C2779617845 @default.
• W3178994804 hasConceptScore W3178994804C2908647359 @default.
• W3178994804 hasConceptScore W3178994804C41008148 @default.
• W3178994804 hasConceptScore W3178994804C54355233 @default.
• W3178994804 hasConceptScore W3178994804C71924100 @default.
• W3178994804 hasConceptScore W3178994804C71928629 @default.
• W3178994804 hasConceptScore W3178994804C761482 @default.
• W3178994804 hasConceptScore W3178994804C78458016 @default.
• W3178994804 hasConceptScore W3178994804C86803240 @default.
• W3178994804 hasConceptScore W3178994804C99454951 @default.
• W3178994804 hasLocation W31789948041 @default.
• W3178994804 hasOpenAccess W3178994804 @default.
• W3178994804 hasPrimaryLocation W31789948041 @default.
• W3178994804 hasRelatedWork W1499342446 @default.
• W3178994804 hasRelatedWork W2036757571 @default.
• W3178994804 hasRelatedWork W2047577613 @default.
• W3178994804 hasRelatedWork W2055008118 @default.
• W3178994804 hasRelatedWork W2076978999 @default.
• W3178994804 hasRelatedWork W2077100517 @default.
• W3178994804 hasRelatedWork W2095552753 @default.
• W3178994804 hasRelatedWork W2103343452 @default.
• W3178994804 hasRelatedWork W2143456696 @default.
• W3178994804 hasRelatedWork W2467407056 @default.
• W3178994804 hasRelatedWork W2588184413 @default.
• W3178994804 hasRelatedWork W2773685302 @default.

• next