FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3179567365> ?p ?o ?g. }

• W3179567365 endingPage "234" @default.
• W3179567365 startingPage "227" @default.
• W3179567365 abstract "High sodium intake is an important risk factor for hypertension and cardiovascular disease. However, the association between gut microbiota composition and metabolomic profiles with dietary sodium intake and blood pressure (BP) is not well-understood. The metabolome, microbiome, and dietary salt intervention (MetaSalt) study aimed to investigate microbial and metabolomic profiles related to dietary sodium intake and BP regulation.This family-based intervention study was conducted in four communities across three provinces in rural northern China in 2019. Probands with untreated prehypertension or stage-1 hypertension were identified through community-based BP screening, and family members including siblings, offspring, spouses, and parents were subsequently included. All participants participated in a 3-day baseline examination with usual diet consumption, followed by a 10-day low-salt diet (3 g/d of salt or 51.3 mmol/d of sodium) and a 10-day high-salt diet (18 g/d of salt or 307.8 mmol/d of sodium). Differences in mean BP levels were compared according to the intervention phases using a paired Student's t-test.A total of 528 participants were included in this study, with a mean age of 48.1 years, 36.7% of whom were male, 76.8% had a middle school (69.7%) or higher (7.1%) diploma, 23.4% had a history of smoking, and 24.4% were current drinkers. The mean arterial pressure at baseline was 97.2 ± 10.5 mm Hg for all participants, and significantly decreased during the low-salt intervention (93.8 ± 9.3, P < 0.0001) and subsequently increased during the high-salt intervention (96.4 ± 10.0, P < 0.0001).Our dietary salt intervention study has successfully recruited participants and will facilitate to evaluate the effects of gut microbiota and metabolites on BP regulation in response to sodium burden, which will provide important evidence for investigating the underlying mechanisms in the development of hypertension and subsequent cardiovascular diseases.The study was registered in the Chinese Clinical Trial Registry database (ChiCTR1900025171)." @default.
• W3179567365 created "2021-07-19" @default.
• W3179567365 creator A5003642180 @default.
• W3179567365 creator A5010186574 @default.
• W3179567365 creator A5016374699 @default.
• W3179567365 creator A5021160495 @default.
• W3179567365 creator A5029299515 @default.
• W3179567365 creator A5038832637 @default.
• W3179567365 creator A5039488838 @default.
• W3179567365 creator A5050700780 @default.
• W3179567365 creator A5053677811 @default.
• W3179567365 creator A5066709636 @default.
• W3179567365 creator A5067633456 @default.
• W3179567365 creator A5070328052 @default.
• W3179567365 creator A5079235161 @default.
• W3179567365 creator A5085361536 @default.
• W3179567365 creator A5091598063 @default.
• W3179567365 date "2021-12-01" @default.
• W3179567365 modified "2023-10-17" @default.
• W3179567365 title "Study design, general characteristics of participants, and preliminary findings from the metabolome, microbiome, and dietary salt intervention study (MetaSalt)" @default.
• W3179567365 cites W1973744659 @default.
• W3179567365 cites W1987127105 @default.
• W3179567365 cites W2021460176 @default.
• W3179567365 cites W2029265484 @default.
• W3179567365 cites W20421448 @default.
• W3179567365 cites W2067168741 @default.
• W3179567365 cites W2502302520 @default.
• W3179567365 cites W2507437074 @default.
• W3179567365 cites W2572331255 @default.
• W3179567365 cites W2587920463 @default.
• W3179567365 cites W2619599864 @default.
• W3179567365 cites W2751936835 @default.
• W3179567365 cites W2753990837 @default.
• W3179567365 cites W2769170966 @default.
• W3179567365 cites W2789762868 @default.
• W3179567365 cites W2801388770 @default.
• W3179567365 cites W2808609072 @default.
• W3179567365 cites W2896968341 @default.
• W3179567365 cites W2899161665 @default.
• W3179567365 cites W2948485373 @default.
• W3179567365 cites W2954533492 @default.
• W3179567365 cites W2978993057 @default.
• W3179567365 cites W2989056639 @default.
• W3179567365 cites W3006040663 @default.
• W3179567365 cites W3081622467 @default.
• W3179567365 cites W3083341372 @default.
• W3179567365 cites W3085021865 @default.
• W3179567365 cites W3092015174 @default.
• W3179567365 cites W3092861045 @default.
• W3179567365 cites W3111548115 @default.
• W3179567365 cites W3117153419 @default.
• W3179567365 cites W4248519369 @default.
• W3179567365 doi "https://doi.org/10.1016/j.cdtm.2021.06.002" @default.
• W3179567365 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8579015" @default.
• W3179567365 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34786542" @default.
• W3179567365 hasPublicationYear "2021" @default.
• W3179567365 type Work @default.
• W3179567365 sameAs 3179567365 @default.
• W3179567365 citedByCount "0" @default.
• W3179567365 crossrefType "journal-article" @default.
• W3179567365 hasAuthorship W3179567365A5003642180 @default.
• W3179567365 hasAuthorship W3179567365A5010186574 @default.
• W3179567365 hasAuthorship W3179567365A5016374699 @default.
• W3179567365 hasAuthorship W3179567365A5021160495 @default.
• W3179567365 hasAuthorship W3179567365A5029299515 @default.
• W3179567365 hasAuthorship W3179567365A5038832637 @default.
• W3179567365 hasAuthorship W3179567365A5039488838 @default.
• W3179567365 hasAuthorship W3179567365A5050700780 @default.
• W3179567365 hasAuthorship W3179567365A5053677811 @default.
• W3179567365 hasAuthorship W3179567365A5066709636 @default.
• W3179567365 hasAuthorship W3179567365A5067633456 @default.
• W3179567365 hasAuthorship W3179567365A5070328052 @default.
• W3179567365 hasAuthorship W3179567365A5079235161 @default.
• W3179567365 hasAuthorship W3179567365A5085361536 @default.
• W3179567365 hasAuthorship W3179567365A5091598063 @default.
• W3179567365 hasBestOaLocation W31795673651 @default.
• W3179567365 hasConcept C112672928 @default.
• W3179567365 hasConcept C118190526 @default.
• W3179567365 hasConcept C126322002 @default.
• W3179567365 hasConcept C135870905 @default.
• W3179567365 hasConcept C143121216 @default.
• W3179567365 hasConcept C2777477808 @default.
• W3179567365 hasConcept C2779234561 @default.
• W3179567365 hasConcept C2781179581 @default.
• W3179567365 hasConcept C42407357 @default.
• W3179567365 hasConcept C54355233 @default.
• W3179567365 hasConcept C60644358 @default.
• W3179567365 hasConcept C71924100 @default.
• W3179567365 hasConcept C84393581 @default.
• W3179567365 hasConcept C86803240 @default.
• W3179567365 hasConceptScore W3179567365C112672928 @default.
• W3179567365 hasConceptScore W3179567365C118190526 @default.
• W3179567365 hasConceptScore W3179567365C126322002 @default.
• W3179567365 hasConceptScore W3179567365C135870905 @default.
• W3179567365 hasConceptScore W3179567365C143121216 @default.
• W3179567365 hasConceptScore W3179567365C2777477808 @default.
• W3179567365 hasConceptScore W3179567365C2779234561 @default.
• W3179567365 hasConceptScore W3179567365C2781179581 @default.

• next