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• W3179668670 abstract "The silkworm gut microbiome is very complex, dynamic and heterogeneous in nature. The beneficial gut microbiome plays essential roles in nutrient acquisition, digestion, absorption, growth, development, immunity response and environmental adaptation. Therefore it is essential to understand the dynamics of the gut microbial members and their interactions with the host insects. However, conventional culture-based methods used in the laboratories are insufficient, as they support the growth of less than 1% of microorganisms. Due to current progress in genomics and sequencing methodologies, microbial community studies using culture independent molecular procedures have begun a new epoch of insect microbial ecology. Recent developments in molecular “Omic techniques” such as metagenomics, and metatranscriptomics has gained a lot of momentum in silkworm microbiology and these techniques have been recently utilized to understand microbial community structure, services and their interactions with silkworms at the micro-scale. Omic techniques have revealed phenomenal microbial diversity in silkworm gut samples. The diversity and distribution of the gut microbiome is significantly influenced by larval developmental stages, gender, feeding, pesticides, environmental perturbations and pathogenesis. In this chapter, different high throughput sequencing technologies (molecular “Omic techniques”) and their limitations will be addressed. The present chapter provides an update on the recent technological advances and emerging trends in exploring gut microbial communities in silkworms towards translation research particularly to understand microbiome functions." @default.
• W3179668670 created "2021-07-19" @default.
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• W3179668670 date "2021-01-01" @default.
• W3179668670 modified "2023-09-23" @default.
• W3179668670 title "Genomics and omics tools to assess complex microbial communities in silkworms: A paradigm shift towards translational research" @default.
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