Matches in SemOpenAlex for { <https://semopenalex.org/work/W3179854736> ?p ?o ?g. }
- W3179854736 abstract "Chronic inflammation generated by the tumor microenvironment is known to drive cancer initiation, proliferation, progression, metastasis, and therapeutic resistance. The tumor microenvironment promotes the secretion of diverse cytokines, in different types and stages of cancers. These cytokines may inhibit tumor development but alternatively may contribute to chronic inflammation that supports tumor growth in both autocrine and paracrine manners and have been linked to poor cancer outcomes. Such distinct sets of cytokines from the tumor microenvironment can be detected in the circulation and are thus potentially useful as biomarkers to detect cancers, predict disease outcomes and manage therapeutic choices. Indeed, analyses of circulating cytokines in combination with cancer-specific biomarkers have been proposed to simplify and improve cancer detection and prognosis, especially from minimally-invasive liquid biopsies, such as blood. Additionally, the cytokine signaling signatures of the peripheral immune cells, even from patients with localized tumors, are recently found altered in cancer, and may also prove applicable as cancer biomarkers. Here we review cytokines induced by the tumor microenvironment, their roles in various stages of cancer development, and their potential use in diagnostics and prognostics. We further discuss the established and emerging diagnostic approaches that can be used to detect cancers from liquid biopsies, and additionally the technological advancement required for their use in clinical settings." @default.
- W3179854736 created "2021-07-19" @default.
- W3179854736 creator A5041919053 @default.
- W3179854736 creator A5041927107 @default.
- W3179854736 creator A5070150682 @default.
- W3179854736 creator A5076987385 @default.
- W3179854736 date "2021-07-07" @default.
- W3179854736 modified "2023-10-14" @default.
- W3179854736 title "Tumor-Induced Inflammatory Cytokines and the Emerging Diagnostic Devices for Cancer Detection and Prognosis" @default.
- W3179854736 cites W1543099628 @default.
- W3179854736 cites W1588727248 @default.
- W3179854736 cites W1760215417 @default.
- W3179854736 cites W1779148422 @default.
- W3179854736 cites W1806464343 @default.
- W3179854736 cites W1953357409 @default.
- W3179854736 cites W1963717723 @default.
- W3179854736 cites W1963842765 @default.
- W3179854736 cites W1963977752 @default.
- W3179854736 cites W1964984840 @default.
- W3179854736 cites W1965037168 @default.
- W3179854736 cites W1965385036 @default.
- W3179854736 cites W1970062660 @default.
- W3179854736 cites W1976121079 @default.
- W3179854736 cites W1977093496 @default.
- W3179854736 cites W1977149080 @default.
- W3179854736 cites W1977264674 @default.
- W3179854736 cites W1980425802 @default.
- W3179854736 cites W1985458516 @default.
- W3179854736 cites W1990211442 @default.
- W3179854736 cites W1995778320 @default.
- W3179854736 cites W1997379610 @default.
- W3179854736 cites W2001417550 @default.
- W3179854736 cites W2003544627 @default.
- W3179854736 cites W2003578515 @default.
- W3179854736 cites W2005396583 @default.
- W3179854736 cites W2006992975 @default.
- W3179854736 cites W2010695266 @default.
- W3179854736 cites W2012751087 @default.
- W3179854736 cites W2014357898 @default.
- W3179854736 cites W2014737409 @default.
- W3179854736 cites W2014899914 @default.
- W3179854736 cites W2018161050 @default.
- W3179854736 cites W2018335660 @default.
- W3179854736 cites W2018752396 @default.
- W3179854736 cites W2021618744 @default.
- W3179854736 cites W2023912603 @default.
- W3179854736 cites W2025806971 @default.
- W3179854736 cites W2031679538 @default.
- W3179854736 cites W2033692444 @default.
- W3179854736 cites W2036802163 @default.
- W3179854736 cites W2041204531 @default.
- W3179854736 cites W2042102689 @default.
- W3179854736 cites W2042953506 @default.
- W3179854736 cites W2043935483 @default.
- W3179854736 cites W2044748328 @default.
- W3179854736 cites W2047158998 @default.
- W3179854736 cites W2048187944 @default.
- W3179854736 cites W2048270654 @default.
- W3179854736 cites W2048657818 @default.
- W3179854736 cites W2050852029 @default.
- W3179854736 cites W2051133720 @default.
- W3179854736 cites W2051473737 @default.
- W3179854736 cites W2053204237 @default.
- W3179854736 cites W2057968053 @default.
- W3179854736 cites W2058239128 @default.
- W3179854736 cites W2058348424 @default.
- W3179854736 cites W2060070314 @default.
- W3179854736 cites W2061168691 @default.
- W3179854736 cites W2061548364 @default.
- W3179854736 cites W2065672938 @default.
- W3179854736 cites W2069825538 @default.
- W3179854736 cites W2070519801 @default.
- W3179854736 cites W2071462181 @default.
- W3179854736 cites W2072270184 @default.
- W3179854736 cites W2076680752 @default.
- W3179854736 cites W2076816261 @default.
- W3179854736 cites W2077246243 @default.
- W3179854736 cites W2079321730 @default.
- W3179854736 cites W2082815124 @default.
- W3179854736 cites W2084131959 @default.
- W3179854736 cites W2087075862 @default.
- W3179854736 cites W2092198587 @default.
- W3179854736 cites W2094267167 @default.
- W3179854736 cites W2098913562 @default.
- W3179854736 cites W2099257830 @default.
- W3179854736 cites W2102365935 @default.
- W3179854736 cites W2104525153 @default.
- W3179854736 cites W2107398189 @default.
- W3179854736 cites W2107432965 @default.
- W3179854736 cites W2110567472 @default.
- W3179854736 cites W2114639059 @default.
- W3179854736 cites W2116490593 @default.
- W3179854736 cites W2116765339 @default.
- W3179854736 cites W2117692326 @default.
- W3179854736 cites W2118291530 @default.
- W3179854736 cites W2119529656 @default.
- W3179854736 cites W2123105952 @default.
- W3179854736 cites W2124076790 @default.
- W3179854736 cites W2124156632 @default.
- W3179854736 cites W2127754394 @default.