Matches in SemOpenAlex for { <https://semopenalex.org/work/W3179898495> ?p ?o ?g. }
- W3179898495 abstract "Current methods in comparative genomic analyses for metabolic potential prediction of proteins involved in, or associated with the Dsr (dissimilatory sulphite reductase)-dependent dissimilatory sulphur metabolism are both time-intensive and computationally challenging, especially when considering metagenomic data. We developed DiSCo, a Dsr-dependent dissimilatory sulphur metabolism classification tool, which automatically identifies and classifies the protein type from sequence data. It takes user-supplied protein sequences and lists the identified proteins and their classification in terms of protein family and predicted type. It can also extract the sequence data from user-input to serve as basis for additional downstream analyses. DiSCo provides the metabolic functional prediction of proteins involved in Dsr-dependent dissimilatory sulphur metabolism with high levels of accuracy in a fast manner. We ran DiSCo against a dataset composed of over 190 thousand (meta)genomic records and efficiently mapped Dsr-dependent dissimilatory sulphur proteins in 1798 lineages across both prokaryotic domains. This allowed the identification of new micro-organisms belonging to Thaumarchaeota and Spirochaetes lineages with the metabolic potential to use the Dsr-pathway for energy conservation. DiSCo is implemented in Perl 5 and freely available under the GNU GPLv3 at https://github.com/Genome-Evolution-and-Ecology-Group-GEEG/DiSCo." @default.
- W3179898495 created "2021-07-19" @default.
- W3179898495 creator A5006492315 @default.
- W3179898495 creator A5063973804 @default.
- W3179898495 date "2021-07-09" @default.
- W3179898495 modified "2023-10-16" @default.
- W3179898495 title "DiSCo: a sequence-based type-specific predictor of Dsr-dependent dissimilatory sulphur metabolism in microbial data" @default.
- W3179898495 cites W1479737627 @default.
- W3179898495 cites W1485088497 @default.
- W3179898495 cites W154786711 @default.
- W3179898495 cites W1589586705 @default.
- W3179898495 cites W1590465348 @default.
- W3179898495 cites W1965488364 @default.
- W3179898495 cites W1966317059 @default.
- W3179898495 cites W1966611271 @default.
- W3179898495 cites W1973290991 @default.
- W3179898495 cites W1974028505 @default.
- W3179898495 cites W1974313209 @default.
- W3179898495 cites W1976325156 @default.
- W3179898495 cites W1983102293 @default.
- W3179898495 cites W1996423252 @default.
- W3179898495 cites W1997435925 @default.
- W3179898495 cites W1999674395 @default.
- W3179898495 cites W2001867962 @default.
- W3179898495 cites W2004073425 @default.
- W3179898495 cites W2006946103 @default.
- W3179898495 cites W2011435726 @default.
- W3179898495 cites W2030534207 @default.
- W3179898495 cites W2034302540 @default.
- W3179898495 cites W2044592649 @default.
- W3179898495 cites W2050791190 @default.
- W3179898495 cites W2055043387 @default.
- W3179898495 cites W2060430727 @default.
- W3179898495 cites W2060633747 @default.
- W3179898495 cites W2065693907 @default.
- W3179898495 cites W2074231493 @default.
- W3179898495 cites W2075704290 @default.
- W3179898495 cites W2082946495 @default.
- W3179898495 cites W2087923912 @default.
- W3179898495 cites W2093776720 @default.
- W3179898495 cites W2099054526 @default.
- W3179898495 cites W2102078274 @default.
- W3179898495 cites W2103382224 @default.
- W3179898495 cites W2111647009 @default.
- W3179898495 cites W2112951169 @default.
- W3179898495 cites W2121139063 @default.
- W3179898495 cites W2124166542 @default.
- W3179898495 cites W2126379089 @default.
- W3179898495 cites W2131832560 @default.
- W3179898495 cites W2131848047 @default.
- W3179898495 cites W2137015675 @default.
- W3179898495 cites W2138122982 @default.
- W3179898495 cites W2138484045 @default.
- W3179898495 cites W2140844264 @default.
- W3179898495 cites W2141305003 @default.
- W3179898495 cites W2141901780 @default.
- W3179898495 cites W2143214215 @default.
- W3179898495 cites W2149096603 @default.
- W3179898495 cites W2152380697 @default.
- W3179898495 cites W2157657843 @default.
- W3179898495 cites W2161379270 @default.
- W3179898495 cites W2161959858 @default.
- W3179898495 cites W2164746782 @default.
- W3179898495 cites W2165824605 @default.
- W3179898495 cites W2166123725 @default.
- W3179898495 cites W2172371128 @default.
- W3179898495 cites W2209765575 @default.
- W3179898495 cites W2224056471 @default.
- W3179898495 cites W2232395788 @default.
- W3179898495 cites W2553911445 @default.
- W3179898495 cites W2710675085 @default.
- W3179898495 cites W2737454466 @default.
- W3179898495 cites W2746754871 @default.
- W3179898495 cites W2750791471 @default.
- W3179898495 cites W2753961085 @default.
- W3179898495 cites W2764029523 @default.
- W3179898495 cites W2783412411 @default.
- W3179898495 cites W2789511815 @default.
- W3179898495 cites W2809027796 @default.
- W3179898495 cites W2883336950 @default.
- W3179898495 cites W2889762847 @default.
- W3179898495 cites W2896231296 @default.
- W3179898495 cites W2903858255 @default.
- W3179898495 cites W2909084307 @default.
- W3179898495 cites W2915106348 @default.
- W3179898495 cites W2915511928 @default.
- W3179898495 cites W2920651455 @default.
- W3179898495 cites W2930346675 @default.
- W3179898495 cites W29354704 @default.
- W3179898495 cites W2948056210 @default.
- W3179898495 cites W2955133522 @default.
- W3179898495 cites W2965788528 @default.
- W3179898495 cites W2979566403 @default.
- W3179898495 cites W2991239467 @default.
- W3179898495 cites W2995819113 @default.
- W3179898495 cites W2998968662 @default.
- W3179898495 cites W3005766622 @default.
- W3179898495 cites W3020822222 @default.
- W3179898495 cites W3040560693 @default.
- W3179898495 cites W3045738847 @default.