Matches in SemOpenAlex for { <https://semopenalex.org/work/W3179960158> ?p ?o ?g. }
- W3179960158 endingPage "3430" @default.
- W3179960158 startingPage "3430" @default.
- W3179960158 abstract "Hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment modality for patients with peritoneal metastasis (PM) of various origins which aims for cure in combination with cytoreductive surgery (CRS). Efficacy of CRS-HIPEC depends on patient selection, tumor type, delivery technique, and treatment parameters such as temperature, carrier solution, type of drug, dosage, volume, and treatment duration. Preclinical research offers a powerful tool to investigate the impact of these parameters and to assist in designing potentially more effective treatment protocols and clinical trials. The different methodologies for peritoneal disease and HIPEC are variable. This study aims to review the objectives, methods, and clinical relevance of in vivo preclinical HIPEC studies found in the literature. In this review, recommendations are provided and possible pitfalls are discussed on the choice of type of animal and tumor model per stratified parameters and study goal. The guidelines presented in this paper can improve the clinical relevance and impact of future in vivo HIPEC experiments." @default.
- W3179960158 created "2021-07-19" @default.
- W3179960158 creator A5013833149 @default.
- W3179960158 creator A5034712204 @default.
- W3179960158 creator A5042130353 @default.
- W3179960158 creator A5046536264 @default.
- W3179960158 creator A5062296352 @default.
- W3179960158 creator A5073552513 @default.
- W3179960158 creator A5074957985 @default.
- W3179960158 creator A5074964050 @default.
- W3179960158 creator A5079636852 @default.
- W3179960158 creator A5080108349 @default.
- W3179960158 creator A5091151627 @default.
- W3179960158 date "2021-07-08" @default.
- W3179960158 modified "2023-10-11" @default.
- W3179960158 title "Preclinical In Vivo-Models to Investigate HIPEC; Current Methodologies and Challenges" @default.
- W3179960158 cites W1590970781 @default.
- W3179960158 cites W1952811152 @default.
- W3179960158 cites W1965883612 @default.
- W3179960158 cites W1968218040 @default.
- W3179960158 cites W1970142260 @default.
- W3179960158 cites W1971203367 @default.
- W3179960158 cites W1973252446 @default.
- W3179960158 cites W1974182212 @default.
- W3179960158 cites W1990789204 @default.
- W3179960158 cites W1993576248 @default.
- W3179960158 cites W1996289824 @default.
- W3179960158 cites W1997722297 @default.
- W3179960158 cites W1998326223 @default.
- W3179960158 cites W1999905581 @default.
- W3179960158 cites W2001318107 @default.
- W3179960158 cites W2015264240 @default.
- W3179960158 cites W2019393736 @default.
- W3179960158 cites W2020667949 @default.
- W3179960158 cites W2021267941 @default.
- W3179960158 cites W2022201484 @default.
- W3179960158 cites W2022288464 @default.
- W3179960158 cites W2032111532 @default.
- W3179960158 cites W2032333533 @default.
- W3179960158 cites W2036235321 @default.
- W3179960158 cites W2039741619 @default.
- W3179960158 cites W2042620152 @default.
- W3179960158 cites W2044357001 @default.
- W3179960158 cites W2053510750 @default.
- W3179960158 cites W2058774212 @default.
- W3179960158 cites W2060621506 @default.
- W3179960158 cites W2062554995 @default.
- W3179960158 cites W2067528579 @default.
- W3179960158 cites W2076232417 @default.
- W3179960158 cites W2077975597 @default.
- W3179960158 cites W2083105156 @default.
- W3179960158 cites W2096102979 @default.
- W3179960158 cites W2116274195 @default.
- W3179960158 cites W2119679457 @default.
- W3179960158 cites W2121909501 @default.
- W3179960158 cites W2133572329 @default.
- W3179960158 cites W2147964292 @default.
- W3179960158 cites W2148971266 @default.
- W3179960158 cites W2163857628 @default.
- W3179960158 cites W2165673818 @default.
- W3179960158 cites W2166820203 @default.
- W3179960158 cites W2170558349 @default.
- W3179960158 cites W2178127438 @default.
- W3179960158 cites W2213062122 @default.
- W3179960158 cites W2226863699 @default.
- W3179960158 cites W2341736937 @default.
- W3179960158 cites W2342217751 @default.
- W3179960158 cites W2405306308 @default.
- W3179960158 cites W2517158042 @default.
- W3179960158 cites W2593411994 @default.
- W3179960158 cites W2594135496 @default.
- W3179960158 cites W2604320614 @default.
- W3179960158 cites W2614165542 @default.
- W3179960158 cites W2754034651 @default.
- W3179960158 cites W2763688233 @default.
- W3179960158 cites W2766182344 @default.
- W3179960158 cites W2771838172 @default.
- W3179960158 cites W2779668451 @default.
- W3179960158 cites W2783622985 @default.
- W3179960158 cites W2784597821 @default.
- W3179960158 cites W2790662053 @default.
- W3179960158 cites W2802524600 @default.
- W3179960158 cites W2810297421 @default.
- W3179960158 cites W2884493376 @default.
- W3179960158 cites W2885018915 @default.
- W3179960158 cites W2890157840 @default.
- W3179960158 cites W2890228749 @default.
- W3179960158 cites W2899370893 @default.
- W3179960158 cites W2910959534 @default.
- W3179960158 cites W2912954165 @default.
- W3179960158 cites W2914878997 @default.
- W3179960158 cites W2944631060 @default.
- W3179960158 cites W2951196366 @default.
- W3179960158 cites W2966631582 @default.
- W3179960158 cites W2967020871 @default.
- W3179960158 cites W2970096104 @default.
- W3179960158 cites W2970149513 @default.
- W3179960158 cites W2973712315 @default.