Matches in SemOpenAlex for { <https://semopenalex.org/work/W3180330053> ?p ?o ?g. }
- W3180330053 endingPage "120157" @default.
- W3180330053 startingPage "120157" @default.
- W3180330053 abstract "• Photobiomodulation (PBM) may be able to improve function of diabetic stem cell. • PBM increases cell viability, and gene expression of antioxidant agents. • PBM decreases population doubling time, apoptosis, and ROS. • PBM decreases gene expression of oxidative stress biomarkers. We studied the effects of photobiomodulation therapy (PBMT) on adipose-derived mesenchymal stem cells (ADSCs) which were extracted from streptozotocin (STZ) induced diabetic rats. Adipose tissue was extracted from the hypodermis of diabetic rats, and diabetic ADSCs were extracted, characterized, and cultured. There were two in vitro groups: control-diabetic ADSCs, and PBMT-diabeticADSCs. We used 630 nm and 810 nm laser at 1.2 J/cm 2 with 3 applications 48 h apart. We measured cell viability, apoptosis, population doubling time (PDT), and reactive oxygen species (ROS) by flow cytometry. Gene expression of antioxidants, including cytosolic copper-zinc superoxide dismutase (SOD1), catalase (CAT), total antioxidant capacity (TAC), and oxidative stress biomarkers (NADPH oxidase 1 and 4) by quantitative real time (qRT) - PCR. In this study, data were analyzed using t -test. Viability of PBMT-diabetic- ADSC group was higher than control- diabetic-ADSC (p = 0.000). PDT and apoptosis of PBMT- diabetic-ADSC group were lower than control-diabetic -ADSC (p = 0.001, p = 0.02). SOD1 expression and TAC of PBMT- diabetic-ADSC group were higher than control –diabetic -ADSC (p = 0.018, p = 0.005). CAT of PBMT –diabetic-ADSC group was higher than control-diabetic -ADSC. ROS, NOX1, and NOX4 of PBMT- diabetic -ADSC group were lower than control-diabetic-ADSC (p = 0.002, p = 0.021, p = 0.017). PBMT may improve diabetic- ADSC function in vitro by increasing levels of cell viability, and gene expression of antioxidant agents (SOD1, CAT, and TAC), and significantly decreasing of levels of PDT, apoptosis, ROS, and gene expression of oxidative stress biomarkers (NOX1 and NOX4)." @default.
- W3180330053 created "2021-07-19" @default.
- W3180330053 creator A5001374433 @default.
- W3180330053 creator A5003882373 @default.
- W3180330053 creator A5012717409 @default.
- W3180330053 creator A5055824840 @default.
- W3180330053 creator A5057069439 @default.
- W3180330053 creator A5066921487 @default.
- W3180330053 creator A5075445175 @default.
- W3180330053 date "2021-12-01" @default.
- W3180330053 modified "2023-09-24" @default.
- W3180330053 title "The effect of photobiomodulation therapy on antioxidants and oxidative stress profiles of adipose derived mesenchymal stem cells in diabetic rats" @default.
- W3180330053 cites W1982051678 @default.
- W3180330053 cites W1993918073 @default.
- W3180330053 cites W2021834384 @default.
- W3180330053 cites W2021840977 @default.
- W3180330053 cites W2031015595 @default.
- W3180330053 cites W2036684796 @default.
- W3180330053 cites W2049445482 @default.
- W3180330053 cites W2066651093 @default.
- W3180330053 cites W2104180183 @default.
- W3180330053 cites W2128473487 @default.
- W3180330053 cites W2135418362 @default.
- W3180330053 cites W2137937538 @default.
- W3180330053 cites W2141271735 @default.
- W3180330053 cites W2145394790 @default.
- W3180330053 cites W2161971786 @default.
- W3180330053 cites W2214373841 @default.
- W3180330053 cites W2528654713 @default.
- W3180330053 cites W2615482484 @default.
- W3180330053 cites W2618924224 @default.
- W3180330053 cites W2740695644 @default.
- W3180330053 cites W2768499679 @default.
- W3180330053 cites W2768877461 @default.
- W3180330053 cites W2782404871 @default.
- W3180330053 cites W2794387698 @default.
- W3180330053 cites W2894195263 @default.
- W3180330053 cites W2899764141 @default.
- W3180330053 cites W2899931186 @default.
- W3180330053 cites W2903135877 @default.
- W3180330053 cites W2912751133 @default.
- W3180330053 cites W2915171406 @default.
- W3180330053 cites W2921766071 @default.
- W3180330053 cites W2944919689 @default.
- W3180330053 cites W2947384314 @default.
- W3180330053 cites W2955941288 @default.
- W3180330053 cites W2968386972 @default.
- W3180330053 cites W2983337144 @default.
- W3180330053 cites W3002040997 @default.
- W3180330053 cites W3006031857 @default.
- W3180330053 cites W3006723048 @default.
- W3180330053 cites W3107188434 @default.
- W3180330053 cites W3108200817 @default.
- W3180330053 cites W3118777252 @default.
- W3180330053 cites W3135192817 @default.
- W3180330053 doi "https://doi.org/10.1016/j.saa.2021.120157" @default.
- W3180330053 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34271236" @default.
- W3180330053 hasPublicationYear "2021" @default.
- W3180330053 type Work @default.
- W3180330053 sameAs 3180330053 @default.
- W3180330053 citedByCount "11" @default.
- W3180330053 countsByYear W31803300532021 @default.
- W3180330053 countsByYear W31803300532022 @default.
- W3180330053 countsByYear W31803300532023 @default.
- W3180330053 crossrefType "journal-article" @default.
- W3180330053 hasAuthorship W3180330053A5001374433 @default.
- W3180330053 hasAuthorship W3180330053A5003882373 @default.
- W3180330053 hasAuthorship W3180330053A5012717409 @default.
- W3180330053 hasAuthorship W3180330053A5055824840 @default.
- W3180330053 hasAuthorship W3180330053A5057069439 @default.
- W3180330053 hasAuthorship W3180330053A5066921487 @default.
- W3180330053 hasAuthorship W3180330053A5075445175 @default.
- W3180330053 hasConcept C134018914 @default.
- W3180330053 hasConcept C142724271 @default.
- W3180330053 hasConcept C171089720 @default.
- W3180330053 hasConcept C198826908 @default.
- W3180330053 hasConcept C2776151105 @default.
- W3180330053 hasConcept C28328180 @default.
- W3180330053 hasConcept C71924100 @default.
- W3180330053 hasConcept C86803240 @default.
- W3180330053 hasConcept C95444343 @default.
- W3180330053 hasConceptScore W3180330053C134018914 @default.
- W3180330053 hasConceptScore W3180330053C142724271 @default.
- W3180330053 hasConceptScore W3180330053C171089720 @default.
- W3180330053 hasConceptScore W3180330053C198826908 @default.
- W3180330053 hasConceptScore W3180330053C2776151105 @default.
- W3180330053 hasConceptScore W3180330053C28328180 @default.
- W3180330053 hasConceptScore W3180330053C71924100 @default.
- W3180330053 hasConceptScore W3180330053C86803240 @default.
- W3180330053 hasConceptScore W3180330053C95444343 @default.
- W3180330053 hasLocation W31803300531 @default.
- W3180330053 hasOpenAccess W3180330053 @default.
- W3180330053 hasPrimaryLocation W31803300531 @default.
- W3180330053 hasRelatedWork W2088394139 @default.
- W3180330053 hasRelatedWork W2292822632 @default.
- W3180330053 hasRelatedWork W2350665201 @default.
- W3180330053 hasRelatedWork W2606223771 @default.
- W3180330053 hasRelatedWork W2783071027 @default.