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- W3180833969 endingPage "4031" @default.
- W3180833969 startingPage "4018" @default.
- W3180833969 abstract "Gram-positive bacterial cell walls are characterised by the presence of a thick peptidoglycan layer which provides protection from extracellular stresses, maintains cell integrity and determines cell morphology, while it also serves as a foundation to anchor a number of crucial polymeric structures. For ovococcal species, including streptococci, enterococci and lactococci, such structures are represented by rhamnose-containing cell wall polysaccharides, which at least in some instances appear to serve as a functional replacement for wall teichoic acids. The biochemical composition of several streptococcal, lactococcal and enterococcal rhamnose-containing cell wall polysaccharides have been elucidated, while associated functional genomic analyses have facilitated the proposition of models for individual biosynthetic pathways. Here, we review the genomic loci which encode the enzymatic machinery to produce rhamnose-containing, cell wall-associated polysaccharide (Rha cwps) structures of the afore-mentioned ovococcal bacteria with particular emphasis on gene content, biochemical structure and common biosynthetic steps. Furthermore, we discuss the role played by these saccharidic polymers as receptors for bacteriophages and the important role phages play in driving Rha cwps diversification and evolution." @default.
- W3180833969 created "2021-07-19" @default.
- W3180833969 creator A5019871566 @default.
- W3180833969 creator A5043395897 @default.
- W3180833969 creator A5061794600 @default.
- W3180833969 date "2021-01-01" @default.
- W3180833969 modified "2023-10-13" @default.
- W3180833969 title "Cell wall polysaccharides of Gram positive ovococcoid bacteria and their role as bacteriophage receptors" @default.
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