FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3181479150> ?p ?o ?g. }

• W3181479150 abstract "Eczema is usually the first allergic manifestation to appear in life attributed to gene-environment interactions. IL13, IL4, MS4A2 and ILR4A are four key inflammatory genes associated with atopy. This study aimed to explore gene-environment interactions on eczema in early life among the above four genes and environmental factors in Chinese Han children.Five hundred ninety-seven children from a birth cohort who completed two-year follow-up were enrolled and their cord blood was collected. Subjects were genotyped for six polymorphisms in the aforementioned four genes. The children were followed at 6, 12 and 24 months, with epidemiologic information and medical history of eczema collected by questionnaire and eczema assessed by dermatologists.Among the 597 children, 168 were diagnosed with eczema and the others were not after 2 years of follow-up. MS4A2 rs569108 GG genotype (P = 1.68E-02, odds ratio (OR) = 4.66) and antibiotic use (P = 3.75E-4, OR = 2.02) were found independently associated with development of childhood eczema. Children with both antibiotic use and MS4A2 rs569108 GG genotype were more likely to develop eczema than those with only antibiotic use or GG homozygote (OR = 6.24 VS. 2.04 or 4.68).MS4A2 rs569108 polymorphism and antibiotic use were solely associated with eczema, and they interacted with each other to increase the risk of developing the disease in Chinese Han toddlers. Long-term follow-up along with functional and replication studies are still needed." @default.
• W3181479150 created "2021-07-19" @default.
• W3181479150 creator A5015189970 @default.
• W3181479150 creator A5018179647 @default.
• W3181479150 creator A5022270161 @default.
• W3181479150 creator A5022831961 @default.
• W3181479150 creator A5027984328 @default.
• W3181479150 creator A5054868514 @default.
• W3181479150 creator A5055723755 @default.
• W3181479150 creator A5056789513 @default.
• W3181479150 creator A5068290128 @default.
• W3181479150 date "2021-07-14" @default.
• W3181479150 modified "2023-10-08" @default.
• W3181479150 title "Interaction between antibiotic use and MS4A2 gene polymorphism on childhood eczema: a prospective birth cohort study" @default.
• W3181479150 cites W1527957830 @default.
• W3181479150 cites W176990180 @default.
• W3181479150 cites W1982906465 @default.
• W3181479150 cites W198427113 @default.
• W3181479150 cites W1988036957 @default.
• W3181479150 cites W1988108185 @default.
• W3181479150 cites W2008754044 @default.
• W3181479150 cites W2029837270 @default.
• W3181479150 cites W2036873130 @default.
• W3181479150 cites W2046024030 @default.
• W3181479150 cites W2049965308 @default.
• W3181479150 cites W2058836799 @default.
• W3181479150 cites W2062210606 @default.
• W3181479150 cites W2105407029 @default.
• W3181479150 cites W2106551918 @default.
• W3181479150 cites W2113624460 @default.
• W3181479150 cites W2147280137 @default.
• W3181479150 cites W2163921908 @default.
• W3181479150 cites W2167790383 @default.
• W3181479150 cites W2175614260 @default.
• W3181479150 cites W2205335459 @default.
• W3181479150 cites W2338760211 @default.
• W3181479150 cites W2425134285 @default.
• W3181479150 cites W2602842300 @default.
• W3181479150 cites W2979688836 @default.
• W3181479150 cites W3007500360 @default.
• W3181479150 cites W4211026773 @default.
• W3181479150 doi "https://doi.org/10.1186/s12887-021-02786-x" @default.
• W3181479150 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8278718" @default.
• W3181479150 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34261469" @default.
• W3181479150 hasPublicationYear "2021" @default.
• W3181479150 type Work @default.
• W3181479150 sameAs 3181479150 @default.
• W3181479150 citedByCount "1" @default.
• W3181479150 countsByYear W31814791502023 @default.
• W3181479150 crossrefType "journal-article" @default.
• W3181479150 hasAuthorship W3181479150A5015189970 @default.
• W3181479150 hasAuthorship W3181479150A5018179647 @default.
• W3181479150 hasAuthorship W3181479150A5022270161 @default.
• W3181479150 hasAuthorship W3181479150A5022831961 @default.
• W3181479150 hasAuthorship W3181479150A5027984328 @default.
• W3181479150 hasAuthorship W3181479150A5054868514 @default.
• W3181479150 hasAuthorship W3181479150A5055723755 @default.
• W3181479150 hasAuthorship W3181479150A5056789513 @default.
• W3181479150 hasAuthorship W3181479150A5068290128 @default.
• W3181479150 hasBestOaLocation W31814791501 @default.
• W3181479150 hasConcept C104317684 @default.
• W3181479150 hasConcept C126322002 @default.
• W3181479150 hasConcept C135763542 @default.
• W3181479150 hasConcept C156957248 @default.
• W3181479150 hasConcept C187212893 @default.
• W3181479150 hasConcept C188816634 @default.
• W3181479150 hasConcept C201903717 @default.
• W3181479150 hasConcept C203014093 @default.
• W3181479150 hasConcept C207480886 @default.
• W3181479150 hasConcept C2777697326 @default.
• W3181479150 hasConcept C54355233 @default.
• W3181479150 hasConcept C71924100 @default.
• W3181479150 hasConcept C72563966 @default.
• W3181479150 hasConcept C86803240 @default.
• W3181479150 hasConceptScore W3181479150C104317684 @default.
• W3181479150 hasConceptScore W3181479150C126322002 @default.
• W3181479150 hasConceptScore W3181479150C135763542 @default.
• W3181479150 hasConceptScore W3181479150C156957248 @default.
• W3181479150 hasConceptScore W3181479150C187212893 @default.
• W3181479150 hasConceptScore W3181479150C188816634 @default.
• W3181479150 hasConceptScore W3181479150C201903717 @default.
• W3181479150 hasConceptScore W3181479150C203014093 @default.
• W3181479150 hasConceptScore W3181479150C207480886 @default.
• W3181479150 hasConceptScore W3181479150C2777697326 @default.
• W3181479150 hasConceptScore W3181479150C54355233 @default.
• W3181479150 hasConceptScore W3181479150C71924100 @default.
• W3181479150 hasConceptScore W3181479150C72563966 @default.
• W3181479150 hasConceptScore W3181479150C86803240 @default.
• W3181479150 hasIssue "1" @default.
• W3181479150 hasLocation W31814791501 @default.
• W3181479150 hasLocation W31814791502 @default.
• W3181479150 hasLocation W31814791503 @default.
• W3181479150 hasOpenAccess W3181479150 @default.
• W3181479150 hasPrimaryLocation W31814791501 @default.
• W3181479150 hasRelatedWork W1981358953 @default.
• W3181479150 hasRelatedWork W1994444007 @default.
• W3181479150 hasRelatedWork W2111356411 @default.
• W3181479150 hasRelatedWork W2119571831 @default.
• W3181479150 hasRelatedWork W2131220512 @default.
• W3181479150 hasRelatedWork W2474132265 @default.

• next