FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3181568360> ?p ?o ?g. }

• W3181568360 endingPage "173221" @default.
• W3181568360 startingPage "173221" @default.
• W3181568360 abstract "The increasingly popular combination of energy drinks containing high amounts of caffeine and alcohol has been shown to induce a stimulated, rather than sedated, state which may result in increased binge drinking and increased risk for alcohol-attributable accidents. We sought to examine consumption patterns of and withdrawal from alcohol and caffeine using a voluntary co-consumption animal model. Male and female adult C57BL/6J mice were given access to increasing doses of caffeine (0.01-0.05%) and/or alcohol (3-20%) in a two-bottle choice, intermittent access voluntary paradigm with fluid consumption recorded daily. Anxiety-like behavior during withdrawal was assessed via elevated plus maze or open field test in experiment 2. Increasing both alcohol and caffeine simultaneously in Experiment 1 resulted in no significant changes in co-consumption compared to mice given access to only alcohol or caffeine. Experiment 2 held caffeine concentration steady while slowly increasing alcohol content and resulted in mice consuming more alcohol when it was consumed in tandem with low dose caffeine. Both male and female mice consumed more caffeine when it was paired with alcohol; however, no significant differences were observed during withdrawal behavior. These results suggest that caffeine may dose-dependently positively influence alcohol consumption in mice and echo clinical literature suggesting that caffeine and alcohol together may result in a heightened state of stimulation and lead to further binge drinking. The intermittent access paradigm affords increased translational validity regarding investigations of alcohol and caffeine co-consumption and may be useful in identifying the neurobiological mechanisms concerning co-consumption of such substances." @default.
• W3181568360 created "2021-07-19" @default.
• W3181568360 creator A5008836118 @default.
• W3181568360 creator A5032371513 @default.
• W3181568360 creator A5042992009 @default.
• W3181568360 date "2021-09-01" @default.
• W3181568360 modified "2023-09-27" @default.
• W3181568360 title "Low but not moderate amounts of caffeine increase co-consumption of ethanol in C57BL/6J mice" @default.
• W3181568360 cites W1842804751 @default.
• W3181568360 cites W1963841728 @default.
• W3181568360 cites W1964160578 @default.
• W3181568360 cites W1987225592 @default.
• W3181568360 cites W1987704070 @default.
• W3181568360 cites W1991486734 @default.
• W3181568360 cites W1992925059 @default.
• W3181568360 cites W1998347339 @default.
• W3181568360 cites W2002233074 @default.
• W3181568360 cites W2010392058 @default.
• W3181568360 cites W2026228200 @default.
• W3181568360 cites W2035445140 @default.
• W3181568360 cites W2047197211 @default.
• W3181568360 cites W2057829605 @default.
• W3181568360 cites W2070721268 @default.
• W3181568360 cites W2074100492 @default.
• W3181568360 cites W2083307405 @default.
• W3181568360 cites W2086531235 @default.
• W3181568360 cites W2093337711 @default.
• W3181568360 cites W2107258454 @default.
• W3181568360 cites W2109813939 @default.
• W3181568360 cites W2114973271 @default.
• W3181568360 cites W2120549275 @default.
• W3181568360 cites W2122062108 @default.
• W3181568360 cites W2125683879 @default.
• W3181568360 cites W2133180168 @default.
• W3181568360 cites W2136192897 @default.
• W3181568360 cites W2141181166 @default.
• W3181568360 cites W2144350112 @default.
• W3181568360 cites W2150266199 @default.
• W3181568360 cites W2153492978 @default.
• W3181568360 cites W2170017401 @default.
• W3181568360 cites W2295263126 @default.
• W3181568360 cites W2314874570 @default.
• W3181568360 cites W2462739799 @default.
• W3181568360 cites W2782412771 @default.
• W3181568360 cites W2788553801 @default.
• W3181568360 cites W3007700117 @default.
• W3181568360 doi "https://doi.org/10.1016/j.pbb.2021.173221" @default.
• W3181568360 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34237301" @default.
• W3181568360 hasPublicationYear "2021" @default.
• W3181568360 type Work @default.
• W3181568360 sameAs 3181568360 @default.
• W3181568360 citedByCount "0" @default.
• W3181568360 crossrefType "journal-article" @default.
• W3181568360 hasAuthorship W3181568360A5008836118 @default.
• W3181568360 hasAuthorship W3181568360A5032371513 @default.
• W3181568360 hasAuthorship W3181568360A5042992009 @default.
• W3181568360 hasConcept C118552586 @default.
• W3181568360 hasConcept C126322002 @default.
• W3181568360 hasConcept C134018914 @default.
• W3181568360 hasConcept C15744967 @default.
• W3181568360 hasConcept C173586616 @default.
• W3181568360 hasConcept C185592680 @default.
• W3181568360 hasConcept C190385971 @default.
• W3181568360 hasConcept C2776610969 @default.
• W3181568360 hasConcept C2776679223 @default.
• W3181568360 hasConcept C2778500429 @default.
• W3181568360 hasConcept C2780161600 @default.
• W3181568360 hasConcept C2781066024 @default.
• W3181568360 hasConcept C3017944768 @default.
• W3181568360 hasConcept C3019635848 @default.
• W3181568360 hasConcept C42407357 @default.
• W3181568360 hasConcept C55493867 @default.
• W3181568360 hasConcept C558461103 @default.
• W3181568360 hasConcept C71924100 @default.
• W3181568360 hasConcept C99454951 @default.
• W3181568360 hasConceptScore W3181568360C118552586 @default.
• W3181568360 hasConceptScore W3181568360C126322002 @default.
• W3181568360 hasConceptScore W3181568360C134018914 @default.
• W3181568360 hasConceptScore W3181568360C15744967 @default.
• W3181568360 hasConceptScore W3181568360C173586616 @default.
• W3181568360 hasConceptScore W3181568360C185592680 @default.
• W3181568360 hasConceptScore W3181568360C190385971 @default.
• W3181568360 hasConceptScore W3181568360C2776610969 @default.
• W3181568360 hasConceptScore W3181568360C2776679223 @default.
• W3181568360 hasConceptScore W3181568360C2778500429 @default.
• W3181568360 hasConceptScore W3181568360C2780161600 @default.
• W3181568360 hasConceptScore W3181568360C2781066024 @default.
• W3181568360 hasConceptScore W3181568360C3017944768 @default.
• W3181568360 hasConceptScore W3181568360C3019635848 @default.
• W3181568360 hasConceptScore W3181568360C42407357 @default.
• W3181568360 hasConceptScore W3181568360C55493867 @default.
• W3181568360 hasConceptScore W3181568360C558461103 @default.
• W3181568360 hasConceptScore W3181568360C71924100 @default.
• W3181568360 hasConceptScore W3181568360C99454951 @default.
• W3181568360 hasFunder F4320309016 @default.
• W3181568360 hasFunder F4320309407 @default.
• W3181568360 hasLocation W31815683601 @default.
• W3181568360 hasLocation W31815683602 @default.

• next