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- W3182014148 abstract "Microtubules (MTs) are hollow cytoskeletons with typically 15 nm inner diameter, which are crucial for various cellular activities including structural support, transport, and cell division. Because of their importance in cells and their unique structural properties, MTs are recognized not only as important targets for cell manipulation but also as interesting components for material applications. However, a methodology for modulation of the properties and functions of MTs is not established. The outside of MTs is historically well-studied, however, the inside of MTs is a recently emerged area. Since various proteins have been recently found inside MTs and are recognized as modulators of MTs, the MT interior has great potential as a reaction field for artificial modulation of the properties and functions. To demonstrate proof-of-concept, we developed Tau-derived peptides that bind to the inner surface of MTs for molecular encapsulation. In this account, we overview the properties of MTs and recent MT-related research, in particular about the inside of MTs, and our approach to encapsulate nanomaterials for modulation of MTs using Tau-derived peptides. The encapsulation of nanomaterials is a new concept for artificial modulation of MTs and would provide insight into the understanding of MTs and cellular and material applications." @default.
- W3182014148 created "2021-07-19" @default.
- W3182014148 creator A5061390597 @default.
- W3182014148 creator A5091604953 @default.
- W3182014148 date "2021-08-15" @default.
- W3182014148 modified "2023-09-29" @default.
- W3182014148 title "Modulation of Microtubule Properties and Functions by Encapsulation of Nanomaterials Using a Tau-Derived Peptide" @default.
- W3182014148 cites W1503265874 @default.
- W3182014148 cites W1546474542 @default.
- W3182014148 cites W1576533924 @default.
- W3182014148 cites W1666768116 @default.
- W3182014148 cites W1785817244 @default.
- W3182014148 cites W1812536929 @default.
- W3182014148 cites W1830376997 @default.
- W3182014148 cites W1963485154 @default.
- W3182014148 cites W1965332656 @default.
- W3182014148 cites W1965404941 @default.
- W3182014148 cites W1967671116 @default.
- W3182014148 cites W1971579914 @default.
- W3182014148 cites W1971859655 @default.
- W3182014148 cites W1975533327 @default.
- W3182014148 cites W1977824626 @default.
- W3182014148 cites W1979267745 @default.
- W3182014148 cites W1979354288 @default.
- W3182014148 cites W1984191940 @default.
- W3182014148 cites W1984939118 @default.
- W3182014148 cites W1988096651 @default.
- W3182014148 cites W1988516828 @default.
- W3182014148 cites W1992969739 @default.
- W3182014148 cites W1993370257 @default.
- W3182014148 cites W1994345832 @default.
- W3182014148 cites W1997012328 @default.
- W3182014148 cites W2001455870 @default.
- W3182014148 cites W2003303711 @default.
- W3182014148 cites W2005731414 @default.
- W3182014148 cites W2007767946 @default.
- W3182014148 cites W2007932941 @default.
- W3182014148 cites W2012810011 @default.
- W3182014148 cites W2013766766 @default.
- W3182014148 cites W2014235423 @default.
- W3182014148 cites W2015171213 @default.
- W3182014148 cites W2018876773 @default.
- W3182014148 cites W2020244288 @default.
- W3182014148 cites W2020270282 @default.
- W3182014148 cites W2022417585 @default.
- W3182014148 cites W2022616146 @default.
- W3182014148 cites W2030209543 @default.
- W3182014148 cites W2046356064 @default.
- W3182014148 cites W2047948963 @default.
- W3182014148 cites W2049225918 @default.
- W3182014148 cites W2052309340 @default.
- W3182014148 cites W2056707942 @default.
- W3182014148 cites W2058036222 @default.
- W3182014148 cites W2058997498 @default.
- W3182014148 cites W2063070514 @default.
- W3182014148 cites W2068451435 @default.
- W3182014148 cites W2070407552 @default.
- W3182014148 cites W2070599389 @default.
- W3182014148 cites W2073758513 @default.
- W3182014148 cites W2083226227 @default.
- W3182014148 cites W2087316744 @default.
- W3182014148 cites W2088585454 @default.
- W3182014148 cites W2092723382 @default.
- W3182014148 cites W2093855538 @default.
- W3182014148 cites W2101513799 @default.
- W3182014148 cites W2108011758 @default.
- W3182014148 cites W2116646168 @default.
- W3182014148 cites W2122759959 @default.
- W3182014148 cites W2125985978 @default.
- W3182014148 cites W2127405396 @default.
- W3182014148 cites W2129885165 @default.
- W3182014148 cites W2129952149 @default.
- W3182014148 cites W2136198266 @default.
- W3182014148 cites W2137036197 @default.
- W3182014148 cites W2140274087 @default.
- W3182014148 cites W2150759583 @default.
- W3182014148 cites W2154158982 @default.
- W3182014148 cites W2157319245 @default.
- W3182014148 cites W2157585070 @default.
- W3182014148 cites W2162785195 @default.
- W3182014148 cites W2163802608 @default.
- W3182014148 cites W2168816122 @default.
- W3182014148 cites W2172275653 @default.
- W3182014148 cites W2276736055 @default.
- W3182014148 cites W2286348179 @default.
- W3182014148 cites W2293277814 @default.
- W3182014148 cites W2309951498 @default.
- W3182014148 cites W2314934032 @default.
- W3182014148 cites W2315673803 @default.
- W3182014148 cites W2325518962 @default.
- W3182014148 cites W2326657447 @default.
- W3182014148 cites W2329426071 @default.
- W3182014148 cites W2335574795 @default.
- W3182014148 cites W2419510842 @default.
- W3182014148 cites W2564082433 @default.
- W3182014148 cites W2592312290 @default.
- W3182014148 cites W2593859967 @default.
- W3182014148 cites W2594014878 @default.