FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3182042175> ?p ?o ?g. }

• W3182042175 abstract "Abstract Funding Acknowledgements Type of funding sources: None. Background The apical variant of hypertrophic cardiomyopathy (ApHCM) has male predominance and is a relatively rare phenotype in Western population. Characteristics of female and black patients diagnosed with ApHCM are very limited in the existing literature. Purpose We aimed to investigate whether gender and race are associated with a different clinical presentation and CMR findings in apical HCM. Methods We retrospectively analysed 150 patients (113 males and 37 females) with a diagnosis of apical HCM who have been followed in our inherited cardiac conditions (ICC) clinic between 2010 and 2020. Only patients with a CMR study and apical hypertrophy defined as ≥ 13mm at the time of diagnosis were included. Demographics and clinical characteristics were obtained from electronic records. Volumetric CMR data were taken from confirmed reports while other parameters were measured by standard protocol. Pure ApHCM was defined as isolated apical hypertrophy and mixed with both apical and septal hypertrophy but with the apex thickest (1). Apical displacement of papillary muscles (PM) was defined when the base of PM originated from the apical one-third of the left ventricle (LV) in the apical 4- or 2-chamber views. Giant T-wave inversion was defined as T-wave inversion that is equal or greater than 10 mm (1 mV) in any electrocardiogram lead. Results Our study population included patients of White (55, 37%), Black (37, 25%), Asian (36, 24%) and Mixed/Others (22, 15%) ethnicity. Black patients were more likely to have a diagnosis of hypertension at presentation when compared to White (70% vs 40%, p = 0.01) and to Asian and Mixed/Other patients (70% vs 48%, p = 0.03). Similarly, they were more likely to have mixed ApHCM than White (49% vs 20%, p = 0.003) and Asian and Mixed/Other (49% vs 26%, p = 0.02) patients. Females were diagnosed at an older age (63 ± 12 vs 52 ± 14, p &lt; 0.001) and were less likely to have deep T-wave inversion on their ECG at presentation (14% vs 32%, p = 0.03) compared to their male counterparts. Females in this cohort also had higher representation of black ethnicity and were more likely to have hypertension (68% vs 47%, p = 0.03). Apart from the expected gender related differences in volumes and LV mass, there were no differences in cardiomyopathy-specific parameters we investigated. Conclusions In our cohort, females with ApHCM presented at an older age and were less likely to have giant T-wave inversion on ECG. Black patients with ApHCM were more likely to have hypertension and the mixed type of the disease." @default.
• W3182042175 created "2021-07-19" @default.
• W3182042175 creator A5000896149 @default.
• W3182042175 creator A5005889333 @default.
• W3182042175 creator A5007925883 @default.
• W3182042175 creator A5015370700 @default.
• W3182042175 creator A5045357003 @default.
• W3182042175 creator A5048966647 @default.
• W3182042175 creator A5066452769 @default.
• W3182042175 date "2021-06-01" @default.
• W3182042175 modified "2023-09-26" @default.
• W3182042175 title "Race, gender and clinical presentation in apical hypertrophic cardiomyopathy" @default.
• W3182042175 doi "https://doi.org/10.1093/ehjci/jeab090.113" @default.
• W3182042175 hasPublicationYear "2021" @default.
• W3182042175 type Work @default.
• W3182042175 sameAs 3182042175 @default.
• W3182042175 citedByCount "0" @default.
• W3182042175 crossrefType "journal-article" @default.
• W3182042175 hasAuthorship W3182042175A5000896149 @default.
• W3182042175 hasAuthorship W3182042175A5005889333 @default.
• W3182042175 hasAuthorship W3182042175A5007925883 @default.
• W3182042175 hasAuthorship W3182042175A5015370700 @default.
• W3182042175 hasAuthorship W3182042175A5045357003 @default.
• W3182042175 hasAuthorship W3182042175A5048966647 @default.
• W3182042175 hasAuthorship W3182042175A5066452769 @default.
• W3182042175 hasBestOaLocation W31820421751 @default.
• W3182042175 hasConcept C126322002 @default.
• W3182042175 hasConcept C141071460 @default.
• W3182042175 hasConcept C164705383 @default.
• W3182042175 hasConcept C167414201 @default.
• W3182042175 hasConcept C192244848 @default.
• W3182042175 hasConcept C2776002628 @default.
• W3182042175 hasConcept C2777601897 @default.
• W3182042175 hasConcept C2778198053 @default.
• W3182042175 hasConcept C2778797674 @default.
• W3182042175 hasConcept C2778921608 @default.
• W3182042175 hasConcept C2780040984 @default.
• W3182042175 hasConcept C2780185194 @default.
• W3182042175 hasConcept C2908647359 @default.
• W3182042175 hasConcept C71924100 @default.
• W3182042175 hasConcept C84393581 @default.
• W3182042175 hasConcept C99454951 @default.
• W3182042175 hasConceptScore W3182042175C126322002 @default.
• W3182042175 hasConceptScore W3182042175C141071460 @default.
• W3182042175 hasConceptScore W3182042175C164705383 @default.
• W3182042175 hasConceptScore W3182042175C167414201 @default.
• W3182042175 hasConceptScore W3182042175C192244848 @default.
• W3182042175 hasConceptScore W3182042175C2776002628 @default.
• W3182042175 hasConceptScore W3182042175C2777601897 @default.
• W3182042175 hasConceptScore W3182042175C2778198053 @default.
• W3182042175 hasConceptScore W3182042175C2778797674 @default.
• W3182042175 hasConceptScore W3182042175C2778921608 @default.
• W3182042175 hasConceptScore W3182042175C2780040984 @default.
• W3182042175 hasConceptScore W3182042175C2780185194 @default.
• W3182042175 hasConceptScore W3182042175C2908647359 @default.
• W3182042175 hasConceptScore W3182042175C71924100 @default.
• W3182042175 hasConceptScore W3182042175C84393581 @default.
• W3182042175 hasConceptScore W3182042175C99454951 @default.
• W3182042175 hasIssue "Supplement_2" @default.
• W3182042175 hasLocation W31820421751 @default.
• W3182042175 hasOpenAccess W3182042175 @default.
• W3182042175 hasPrimaryLocation W31820421751 @default.
• W3182042175 hasRelatedWork W1909621880 @default.
• W3182042175 hasRelatedWork W2338999969 @default.
• W3182042175 hasRelatedWork W2398053466 @default.
• W3182042175 hasRelatedWork W2400627207 @default.
• W3182042175 hasRelatedWork W2410630585 @default.
• W3182042175 hasRelatedWork W2422643786 @default.
• W3182042175 hasRelatedWork W3146266170 @default.
• W3182042175 hasRelatedWork W4226001377 @default.
• W3182042175 hasRelatedWork W77824482 @default.
• W3182042175 hasRelatedWork W88813562 @default.
• W3182042175 hasVolume "22" @default.
• W3182042175 isParatext "false" @default.
• W3182042175 isRetracted "false" @default.
• W3182042175 magId "3182042175" @default.
• W3182042175 workType "article" @default.