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- W3182050355 abstract "Objective To determine whether guideline non-adherence is associated with Black race. Methods A retrospective review of National Cancer Database records of women diagnosed with epithelial ovarian cancer from 2012 to 2016 who identified as “White” or “Black” was performed. Exposure was adherence or non-adherence to National Comprehensive Cancer Network guidelines for treatment. Outcomes were differences in disease characteristics and overall survival in months. Results Of the 29,948 eligible patients, 93% (n = 27,744) were White and 7% (n = 2204) were Black. Having stage IV disease (OR 1.45, 95% CI 1.23–1.70; P < 0.001) and treatment in a comprehensive (OR 1.58, 95% CI 1.16–2.15; P = 0.0039) or academic (OR 2.30, 95% CI 1.70–3.12; P < 0.001) treatment facility were associated with Black race. Adherence to guidelines did not predict Black race (OR for adherence 1.0021, 95% CI 0.89–1.13; P = 0.97). Median survival for White patients with adherent care was 63.4 months and 51.4 months for Black patients (P = 0.0001). Median survival for White patients with non-adherent care was 60.5 months and 47.2 months for Black patients (P < 0.0001). Median overall survival was 61.1 months in White patients and 49.3 months in Black patients (P < 0.0001). Conclusions Our data suggest that while Black patients and patients who receive non-NCCN guideline directed care have worse survival outcomes, guideline adherence is not independently associated with Black race. We must consider other socioeconomic, environmental and system factors that are contributing to the survival discrepancy in Black patients with ovarian cancer." @default.
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- W3182050355 date "2021-09-01" @default.
- W3182050355 modified "2023-10-16" @default.
- W3182050355 title "Disparities in ovarian cancer treatment and overall survival according to race: An update" @default.
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- W3182050355 doi "https://doi.org/10.1016/j.ygyno.2021.07.011" @default.
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