FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3182099403> ?p ?o ?g. }

• W3182099403 endingPage "1636" @default.
• W3182099403 startingPage "1630" @default.
• W3182099403 abstract "To assess the efficacy and safety of catheter ablation (CA) compared with antiarrhythmic drugs (AADs) as first-line treatment for symptomatic paroxysmal atrial fibrillation (AF).Systematic review and meta-analysis of randomised controlled trials identified using MEDLINE, Cochrane Library and Embase published between 01/01/2000 and 19/03/2021. The primary efficacy endpoint was the first documented recurrence of atrial arrhythmias following the blanking period. The primary safety endpoint was a composite of all serious adverse events (SAEs).From 441 records, 6 studies met the inclusion criteria. 609 patients received CA, while 603 received AAD therapy. 212/609 patients in the CA group had a recurrence of atrial arrhythmias as compared with 318/603 in the AADs group resulting in a 36% relative risk reduction (risk ratio: 0.64, 95% CI 0.51 to 0.80, p<0.01). The risk of all SAEs was not statistically different between CA and AAD (0.87, 0.58 to 1.30, p=0.49); 107/609 SAE in the CA group vs 126/603 in the AAD group. Both recurrence of symptomatic atrial arrhythmias (109/505 vs 186/504) and healthcare utilisation (126/397 vs 185/394) were significantly lower in the CA group (0.53, 0.35 to 0.79 and 0.65, 0.48 to 0.89, respectively). There was a 79% reduction in the crossover rate during follow-up among patients randomised to CA compared with AAD (0.21, 0.13 to 0.32, p<0.01).First-line treatment with CA is superior to AAD therapy in patients with symptomatic paroxysmal AF, as it significantly reduces the recurrence of any atrial arrhythmias and symptomatic atrial arrhythmias, and healthcare resource utilisation with comparable safety profile." @default.
• W3182099403 created "2021-07-19" @default.
• W3182099403 creator A5027537130 @default.
• W3182099403 creator A5038405190 @default.
• W3182099403 creator A5048738698 @default.
• W3182099403 creator A5052514318 @default.
• W3182099403 creator A5057662312 @default.
• W3182099403 creator A5074433373 @default.
• W3182099403 creator A5081566147 @default.
• W3182099403 creator A5085125532 @default.
• W3182099403 date "2021-07-14" @default.
• W3182099403 modified "2023-10-17" @default.
• W3182099403 title "Catheter ablation as first-line treatment for paroxysmal atrial fibrillation: a systematic review and meta-analysis" @default.
• W3182099403 cites W1770423723 @default.
• W3182099403 cites W1821742232 @default.
• W3182099403 cites W1973633212 @default.
• W3182099403 cites W2073835735 @default.
• W3182099403 cites W2097321917 @default.
• W3182099403 cites W2125891322 @default.
• W3182099403 cites W2133435868 @default.
• W3182099403 cites W2154269490 @default.
• W3182099403 cites W2164489173 @default.
• W3182099403 cites W2242405798 @default.
• W3182099403 cites W2263802714 @default.
• W3182099403 cites W2518330835 @default.
• W3182099403 cites W2564956751 @default.
• W3182099403 cites W2575627433 @default.
• W3182099403 cites W2756350807 @default.
• W3182099403 cites W2767061262 @default.
• W3182099403 cites W2920804236 @default.
• W3182099403 cites W2931213110 @default.
• W3182099403 cites W2970684805 @default.
• W3182099403 cites W3004146394 @default.
• W3182099403 cites W3019350884 @default.
• W3182099403 cites W3082188176 @default.
• W3182099403 cites W3082794714 @default.
• W3182099403 cites W3100870347 @default.
• W3182099403 cites W3101635021 @default.
• W3182099403 cites W3134985462 @default.
• W3182099403 cites W3138837606 @default.
• W3182099403 cites W4294215472 @default.
• W3182099403 doi "https://doi.org/10.1136/heartjnl-2021-319496" @default.
• W3182099403 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34261737" @default.
• W3182099403 hasPublicationYear "2021" @default.
• W3182099403 type Work @default.
• W3182099403 sameAs 3182099403 @default.
• W3182099403 citedByCount "36" @default.
• W3182099403 countsByYear W31820994032021 @default.
• W3182099403 countsByYear W31820994032022 @default.
• W3182099403 countsByYear W31820994032023 @default.
• W3182099403 crossrefType "journal-article" @default.
• W3182099403 hasAuthorship W3182099403A5027537130 @default.
• W3182099403 hasAuthorship W3182099403A5038405190 @default.
• W3182099403 hasAuthorship W3182099403A5048738698 @default.
• W3182099403 hasAuthorship W3182099403A5052514318 @default.
• W3182099403 hasAuthorship W3182099403A5057662312 @default.
• W3182099403 hasAuthorship W3182099403A5074433373 @default.
• W3182099403 hasAuthorship W3182099403A5081566147 @default.
• W3182099403 hasAuthorship W3182099403A5085125532 @default.
• W3182099403 hasConcept C126322002 @default.
• W3182099403 hasConcept C142724271 @default.
• W3182099403 hasConcept C164705383 @default.
• W3182099403 hasConcept C168563851 @default.
• W3182099403 hasConcept C187960798 @default.
• W3182099403 hasConcept C197934379 @default.
• W3182099403 hasConcept C203092338 @default.
• W3182099403 hasConcept C204787440 @default.
• W3182099403 hasConcept C27081682 @default.
• W3182099403 hasConcept C2776131983 @default.
• W3182099403 hasConcept C2776478404 @default.
• W3182099403 hasConcept C2779161974 @default.
• W3182099403 hasConcept C42219234 @default.
• W3182099403 hasConcept C44249647 @default.
• W3182099403 hasConcept C71924100 @default.
• W3182099403 hasConcept C82789193 @default.
• W3182099403 hasConcept C95190672 @default.
• W3182099403 hasConceptScore W3182099403C126322002 @default.
• W3182099403 hasConceptScore W3182099403C142724271 @default.
• W3182099403 hasConceptScore W3182099403C164705383 @default.
• W3182099403 hasConceptScore W3182099403C168563851 @default.
• W3182099403 hasConceptScore W3182099403C187960798 @default.
• W3182099403 hasConceptScore W3182099403C197934379 @default.
• W3182099403 hasConceptScore W3182099403C203092338 @default.
• W3182099403 hasConceptScore W3182099403C204787440 @default.
• W3182099403 hasConceptScore W3182099403C27081682 @default.
• W3182099403 hasConceptScore W3182099403C2776131983 @default.
• W3182099403 hasConceptScore W3182099403C2776478404 @default.
• W3182099403 hasConceptScore W3182099403C2779161974 @default.
• W3182099403 hasConceptScore W3182099403C42219234 @default.
• W3182099403 hasConceptScore W3182099403C44249647 @default.
• W3182099403 hasConceptScore W3182099403C71924100 @default.
• W3182099403 hasConceptScore W3182099403C82789193 @default.
• W3182099403 hasConceptScore W3182099403C95190672 @default.
• W3182099403 hasIssue "20" @default.
• W3182099403 hasLocation W31820994031 @default.
• W3182099403 hasLocation W31820994032 @default.
• W3182099403 hasOpenAccess W3182099403 @default.
• W3182099403 hasPrimaryLocation W31820994031 @default.

• next