Matches in SemOpenAlex for { <https://semopenalex.org/work/W3183260072> ?p ?o ?g. }
- W3183260072 endingPage "102734" @default.
- W3183260072 startingPage "102734" @default.
- W3183260072 abstract "In the current study an Allicin delivering polymeric wound dressing was formulated using thermally induced phase separation method. Allicin was loaded into Chitosan/Polyvinyl Alcohol solution at weight ratios 3 %,5 %, and 10 % and then freeze-dried. The fabricated membrane's physiochemical and biological properties were assessed using scanning electron microscopy, cell viability assay, swelling capacity, mechanical strength, surface wettability, water vapor permeability, drug release profile, in vitro degradation, hemocompatibility, porosity measurement, microbial penetration assay, Anti-oxidant assay, and protein adsorption assay. According to cell MTT assay results, Chitosan/Polyvinyl Alcohol incorporated with 5 % Allicin had the highest cell viability compared with other formulations; therefore, this formulation was chosen for treating rat model of diabetic wounds. The results showed that the rats treated with Allicin loaded dressings exhibited 93.15 ± 6.38 % of wound closure after 14 days. In addition, this group showed 47.11 ± 3.67 μm of epithelial thickness and 72.31 ± 4.28% of collagen deposition at the end of 14th post-wounding. These values were significantly greater than that of Allicin-free dressings and control group, p value < 0.05. These preliminary results suggest potential applicability of Allicin loaded Chitosan/Polyvinyl Alcohol dressing in treating diabetic wounds in clinic." @default.
- W3183260072 created "2021-08-02" @default.
- W3183260072 creator A5009324255 @default.
- W3183260072 creator A5014399762 @default.
- W3183260072 creator A5017448268 @default.
- W3183260072 creator A5026207629 @default.
- W3183260072 creator A5067537591 @default.
- W3183260072 date "2021-10-01" @default.
- W3183260072 modified "2023-10-10" @default.
- W3183260072 title "Allicin-loaded chitosan/polyvinyl alcohol scaffolds as a potential wound dressing material to treat diabetic wounds: An in vitro and in vivo study" @default.
- W3183260072 cites W1888479359 @default.
- W3183260072 cites W191274304 @default.
- W3183260072 cites W1987689427 @default.
- W3183260072 cites W2053326070 @default.
- W3183260072 cites W2056368477 @default.
- W3183260072 cites W2085659839 @default.
- W3183260072 cites W2100439822 @default.
- W3183260072 cites W2105916525 @default.
- W3183260072 cites W2156537511 @default.
- W3183260072 cites W2605424194 @default.
- W3183260072 cites W2622096946 @default.
- W3183260072 cites W2729854624 @default.
- W3183260072 cites W2733366005 @default.
- W3183260072 cites W2735218346 @default.
- W3183260072 cites W2746482619 @default.
- W3183260072 cites W2757019641 @default.
- W3183260072 cites W2763173066 @default.
- W3183260072 cites W2769204254 @default.
- W3183260072 cites W2799343390 @default.
- W3183260072 cites W2800127497 @default.
- W3183260072 cites W2800381029 @default.
- W3183260072 cites W2803879751 @default.
- W3183260072 cites W2804120535 @default.
- W3183260072 cites W2883232768 @default.
- W3183260072 cites W2885551485 @default.
- W3183260072 cites W2888100542 @default.
- W3183260072 cites W2894846143 @default.
- W3183260072 cites W2896039429 @default.
- W3183260072 cites W2900648517 @default.
- W3183260072 cites W2903671194 @default.
- W3183260072 cites W2905423984 @default.
- W3183260072 cites W2910095469 @default.
- W3183260072 cites W2915171406 @default.
- W3183260072 cites W2918876020 @default.
- W3183260072 cites W2921435110 @default.
- W3183260072 cites W2966064397 @default.
- W3183260072 cites W2969621801 @default.
- W3183260072 cites W2974369063 @default.
- W3183260072 cites W2998818461 @default.
- W3183260072 cites W3009701721 @default.
- W3183260072 cites W3012514664 @default.
- W3183260072 cites W3012693198 @default.
- W3183260072 cites W3012720606 @default.
- W3183260072 cites W3028267995 @default.
- W3183260072 cites W3048134077 @default.
- W3183260072 doi "https://doi.org/10.1016/j.jddst.2021.102734" @default.
- W3183260072 hasPublicationYear "2021" @default.
- W3183260072 type Work @default.
- W3183260072 sameAs 3183260072 @default.
- W3183260072 citedByCount "10" @default.
- W3183260072 countsByYear W31832600722021 @default.
- W3183260072 countsByYear W31832600722022 @default.
- W3183260072 countsByYear W31832600722023 @default.
- W3183260072 crossrefType "journal-article" @default.
- W3183260072 hasAuthorship W3183260072A5009324255 @default.
- W3183260072 hasAuthorship W3183260072A5014399762 @default.
- W3183260072 hasAuthorship W3183260072A5017448268 @default.
- W3183260072 hasAuthorship W3183260072A5026207629 @default.
- W3183260072 hasAuthorship W3183260072A5067537591 @default.
- W3183260072 hasConcept C136229726 @default.
- W3183260072 hasConcept C141071460 @default.
- W3183260072 hasConcept C159985019 @default.
- W3183260072 hasConcept C178790620 @default.
- W3183260072 hasConcept C185592680 @default.
- W3183260072 hasConcept C192562407 @default.
- W3183260072 hasConcept C202751555 @default.
- W3183260072 hasConcept C2778540859 @default.
- W3183260072 hasConcept C2778551929 @default.
- W3183260072 hasConcept C2779732960 @default.
- W3183260072 hasConcept C2780269544 @default.
- W3183260072 hasConcept C2780783641 @default.
- W3183260072 hasConcept C2781005338 @default.
- W3183260072 hasConcept C43617362 @default.
- W3183260072 hasConcept C53227056 @default.
- W3183260072 hasConcept C55493867 @default.
- W3183260072 hasConcept C71924100 @default.
- W3183260072 hasConceptScore W3183260072C136229726 @default.
- W3183260072 hasConceptScore W3183260072C141071460 @default.
- W3183260072 hasConceptScore W3183260072C159985019 @default.
- W3183260072 hasConceptScore W3183260072C178790620 @default.
- W3183260072 hasConceptScore W3183260072C185592680 @default.
- W3183260072 hasConceptScore W3183260072C192562407 @default.
- W3183260072 hasConceptScore W3183260072C202751555 @default.
- W3183260072 hasConceptScore W3183260072C2778540859 @default.
- W3183260072 hasConceptScore W3183260072C2778551929 @default.
- W3183260072 hasConceptScore W3183260072C2779732960 @default.
- W3183260072 hasConceptScore W3183260072C2780269544 @default.
- W3183260072 hasConceptScore W3183260072C2780783641 @default.