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- W3183267169 abstract "Machine learning brings the hope of finding new biomarkers extracted from cohorts with rich biomedical measurements. A good biomarker is one that gives reliable detection of the corresponding condition. However, biomarkers are often extracted from a cohort that differs from the target population. Such a mismatch, known as a dataset shift, can undermine the application of the biomarker to new individuals. Dataset shifts are frequent in biomedical research, e.g., because of recruitment biases. When a dataset shift occurs, standard machine-learning techniques do not suffice to extract and validate biomarkers. This article provides an overview of when and how dataset shifts break machine-learning-extracted biomarkers, as well as detection and correction strategies." @default.
- W3183267169 created "2021-08-02" @default.
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- W3183267169 date "2021-09-01" @default.
- W3183267169 modified "2023-10-18" @default.
- W3183267169 title "Preventing dataset shift from breaking machine-learning biomarkers" @default.
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- W3183267169 doi "https://doi.org/10.1093/gigascience/giab055" @default.
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