FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3183441657> ?p ?o ?g. }

• W3183441657 endingPage "105146" @default.
• W3183441657 startingPage "105146" @default.
• W3183441657 abstract "Antibody to hepatitis B core antigen (anti-HBc) is one of the most classical serological markers of HBV infection. This study aimed to investigate the association of serum anti-HBc and HBeAg seroconversion in patients with HBeAg-positive chronic hepatitis B (CHB) after antiviral treatment. Two hundred and seventeen HBeAg-positive CHB patients treated with entecavir (ETV) or tenofovir disoproxil fumarate (TDF) for 48 weeks were retrospectively enrolled. Serological response (SR) is defined as HBeAg seroconversion at 48 weeks of antiviral treatment. Serum anti-HBc level was measured using the Abbott ARCHITECT assay. After 48 weeks of antiviral treatment, twenty-two (10.1 %) patients achieved SR. Baseline level of serum anti-HBc in the SR patients (11.8 S/CO) was significantly higher than patients with non-SR (9.6 S/CO, P < 0.001). The median anti-HBc level was significantly declined after 48 weeks of antiviral therapy (9.9 vs. 8.9 S/CO, P < 0.001). Multivariate logistic regression analysis showed baseline of serum anti-HBc was an independent predictor of SR (odds ratio [OR]: 1.462, 95 % confidence interval [CI] 1.170-1.825, P = 0.001). The area under receiver operating characteristic curve (AUROC) of baseline anti-HBc level for predicting SR was 0.781 with the cut-off of 11.1 S/CO, with a sensitivity of 77.27 % and a specificity of 72.82 %. Our findings highlighted that baseline serum anti-HBc level is a promising indictor for predicting HBeAg seroconversion in HBeAg-positive CHB patients after antiviral treatment." @default.
• W3183441657 created "2021-08-02" @default.
• W3183441657 creator A5007774021 @default.
• W3183441657 creator A5009270956 @default.
• W3183441657 creator A5012657062 @default.
• W3183441657 creator A5023606351 @default.
• W3183441657 creator A5028127962 @default.
• W3183441657 creator A5045949080 @default.
• W3183441657 creator A5058684828 @default.
• W3183441657 creator A5063358317 @default.
• W3183441657 creator A5064869771 @default.
• W3183441657 creator A5069831074 @default.
• W3183441657 creator A5073163963 @default.
• W3183441657 creator A5084575560 @default.
• W3183441657 creator A5086289661 @default.
• W3183441657 date "2021-09-01" @default.
• W3183441657 modified "2023-09-30" @default.
• W3183441657 title "Baseline serum hepatitis B core antibody level predicts HBeAg seroconversion in patients with HBeAg-positive chronic hepatitis B after antiviral treatment" @default.
• W3183441657 cites W1764314633 @default.
• W3183441657 cites W1840083304 @default.
• W3183441657 cites W1985860298 @default.
• W3183441657 cites W2059560167 @default.
• W3183441657 cites W2071476028 @default.
• W3183441657 cites W2099753264 @default.
• W3183441657 cites W2114785561 @default.
• W3183441657 cites W2119674621 @default.
• W3183441657 cites W2145660513 @default.
• W3183441657 cites W2151523434 @default.
• W3183441657 cites W2157942577 @default.
• W3183441657 cites W2159616534 @default.
• W3183441657 cites W2163147639 @default.
• W3183441657 cites W2319441763 @default.
• W3183441657 cites W2339419346 @default.
• W3183441657 cites W2481374159 @default.
• W3183441657 cites W2531646094 @default.
• W3183441657 cites W2559684878 @default.
• W3183441657 cites W2605785536 @default.
• W3183441657 cites W2619926503 @default.
• W3183441657 cites W2734590811 @default.
• W3183441657 cites W2800178113 @default.
• W3183441657 cites W2944023476 @default.
• W3183441657 cites W2978002403 @default.
• W3183441657 doi "https://doi.org/10.1016/j.antiviral.2021.105146" @default.
• W3183441657 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34314774" @default.
• W3183441657 hasPublicationYear "2021" @default.
• W3183441657 type Work @default.
• W3183441657 sameAs 3183441657 @default.
• W3183441657 citedByCount "3" @default.
• W3183441657 countsByYear W31834416572023 @default.
• W3183441657 crossrefType "journal-article" @default.
• W3183441657 hasAuthorship W3183441657A5007774021 @default.
• W3183441657 hasAuthorship W3183441657A5009270956 @default.
• W3183441657 hasAuthorship W3183441657A5012657062 @default.
• W3183441657 hasAuthorship W3183441657A5023606351 @default.
• W3183441657 hasAuthorship W3183441657A5028127962 @default.
• W3183441657 hasAuthorship W3183441657A5045949080 @default.
• W3183441657 hasAuthorship W3183441657A5058684828 @default.
• W3183441657 hasAuthorship W3183441657A5063358317 @default.
• W3183441657 hasAuthorship W3183441657A5064869771 @default.
• W3183441657 hasAuthorship W3183441657A5069831074 @default.
• W3183441657 hasAuthorship W3183441657A5073163963 @default.
• W3183441657 hasAuthorship W3183441657A5084575560 @default.
• W3183441657 hasAuthorship W3183441657A5086289661 @default.
• W3183441657 hasConcept C126322002 @default.
• W3183441657 hasConcept C151956035 @default.
• W3183441657 hasConcept C156957248 @default.
• W3183441657 hasConcept C159654299 @default.
• W3183441657 hasConcept C203014093 @default.
• W3183441657 hasConcept C2522874641 @default.
• W3183441657 hasConcept C2775940106 @default.
• W3183441657 hasConcept C2776175608 @default.
• W3183441657 hasConcept C2777382497 @default.
• W3183441657 hasConcept C2777410769 @default.
• W3183441657 hasConcept C2777451964 @default.
• W3183441657 hasConcept C2777869810 @default.
• W3183441657 hasConcept C2780593183 @default.
• W3183441657 hasConcept C44249647 @default.
• W3183441657 hasConcept C45189115 @default.
• W3183441657 hasConcept C71924100 @default.
• W3183441657 hasConcept C90924648 @default.
• W3183441657 hasConceptScore W3183441657C126322002 @default.
• W3183441657 hasConceptScore W3183441657C151956035 @default.
• W3183441657 hasConceptScore W3183441657C156957248 @default.
• W3183441657 hasConceptScore W3183441657C159654299 @default.
• W3183441657 hasConceptScore W3183441657C203014093 @default.
• W3183441657 hasConceptScore W3183441657C2522874641 @default.
• W3183441657 hasConceptScore W3183441657C2775940106 @default.
• W3183441657 hasConceptScore W3183441657C2776175608 @default.
• W3183441657 hasConceptScore W3183441657C2777382497 @default.
• W3183441657 hasConceptScore W3183441657C2777410769 @default.
• W3183441657 hasConceptScore W3183441657C2777451964 @default.
• W3183441657 hasConceptScore W3183441657C2777869810 @default.
• W3183441657 hasConceptScore W3183441657C2780593183 @default.
• W3183441657 hasConceptScore W3183441657C44249647 @default.
• W3183441657 hasConceptScore W3183441657C45189115 @default.
• W3183441657 hasConceptScore W3183441657C71924100 @default.
• W3183441657 hasConceptScore W3183441657C90924648 @default.
• W3183441657 hasLocation W31834416571 @default.

• next