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• W3183488803 abstract "Abstract Background The legal criteria for medical assistance in dying (MAiD) for adults with a grievous and irremediable medical condition were established in Canada in 2016. There has been concern that potentially reversible states of depression or demoralization may contribute to the desire for death (DD) and requests for MAiD. However, little is known about the emergence of the DD in patients, its impact on caregivers, and to what extent supportive care interventions affect the DD and requests for MAiD. The present observational study is designed to determine the prevalence, predictors, and experience of the DD, requests for MAiD and MAiD completion in patients with advanced or metastatic cancer and the impact of these outcomes on their primary caregivers. Methods A cohort of patients with advanced or metastatic solid tumour cancers and their primary caregivers will be recruited from a large tertiary cancer centre in Toronto, Ontario, Canada, to a longitudinal, mixed methods study. Participants will be assessed at baseline for diagnostic information, sociodemographic characteristics, medical history, quality of life, physical and psychological distress, attitudes about the DD and MAiD, communication with physicians, advance care planning, and use of psychosocial and palliative care interventions. Measures will subsequently be completed every six months and at the time of MAiD requests. Quantitative assessments will be supplemented by qualitative interviews in a subset of participants, selected using quota sampling methods. Discussion This study has the potential to add importantly to our understanding of the prevalence and determinants of the DD, MAiD requests and completions in patients with advanced or metastatic cancer and of the experience of both patients and caregivers in this circumstance. The findings from this study may also assist healthcare providers in their conversations about MAiD and the DD with patients and caregivers, inform healthcare providers to ensure appropriate access to MAiD, and guide modifications being considered to broaden MAiD legislation and policy." @default.
• W3183488803 created "2021-08-02" @default.
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• W3183488803 date "2021-07-21" @default.
• W3183488803 modified "2023-09-26" @default.
• W3183488803 title "Medical Assistance in Dying in patients with advanced cancer and their caregivers: a mixed methods longitudinal study protocol" @default.
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• W3183488803 doi "https://doi.org/10.1186/s12904-021-00793-4" @default.
• W3183488803 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8296526" @default.
• W3183488803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34289838" @default.
• W3183488803 hasPublicationYear "2021" @default.

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