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- W3183669166 abstract "Abstract Respiratory toxicology remains a major research area in the 21st century since current scenario of airborne viral infection transmission and pollutant inhalation is expected to raise the annual morbidity beyond 2 million. Clinical and epidemiological research connecting human exposure to air contaminants to understand adverse pulmonary health outcomes is, therefore, an immediate subject of human health assessment. Important observations in defining systemic effects of environmental contaminants on inhalation metabolic dysfunction, liver health, and gastrointestinal tract have been well explored with in vivo models. In this review, a framework is provided, a paradigm is established about inhalation toxicity testing in vitro, and a brief overview of breathing Lungs‐on‐Chip (LoC) as design concepts is given. The optimized bioengineering approaches and microfluidics with their fundamental pros, and cons are presented. There are different strategies that researchers apply to inhalation toxicity studies to assess a variety of inhalable substances and relevant LoC approaches. A case study from published literature and frame arguments about reproducibility as well as in vitro/in vivo correlations are discussed. Finally, the opportunities and challenges in soft robotics, systems inhalation toxicology approach integrating bioengineering, machine learning, and artificial intelligence to address a multitude model for future toxicology are discussed." @default.
- W3183669166 created "2021-08-02" @default.
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- W3183669166 date "2021-07-22" @default.
- W3183669166 modified "2023-10-16" @default.
- W3183669166 title "Emerging Technologies for In Vitro Inhalation Toxicology" @default.
- W3183669166 cites W1589958073 @default.
- W3183669166 cites W1846363290 @default.
- W3183669166 cites W1965728656 @default.
- W3183669166 cites W1972260639 @default.
- W3183669166 cites W1976750023 @default.
- W3183669166 cites W1979665070 @default.
- W3183669166 cites W1985441171 @default.
- W3183669166 cites W1993540541 @default.
- W3183669166 cites W2000797825 @default.
- W3183669166 cites W2008888516 @default.
- W3183669166 cites W2012297303 @default.
- W3183669166 cites W2018445772 @default.
- W3183669166 cites W2024990391 @default.
- W3183669166 cites W2030932194 @default.
- W3183669166 cites W2035327107 @default.
- W3183669166 cites W2076922024 @default.
- W3183669166 cites W2085026309 @default.
- W3183669166 cites W2094278078 @default.
- W3183669166 cites W2118997818 @default.
- W3183669166 cites W2149565435 @default.
- W3183669166 cites W2151432824 @default.
- W3183669166 cites W2156897318 @default.
- W3183669166 cites W2170637707 @default.
- W3183669166 cites W2306189633 @default.
- W3183669166 cites W2315048020 @default.
- W3183669166 cites W2578024434 @default.
- W3183669166 cites W2591768503 @default.
- W3183669166 cites W2608280010 @default.
- W3183669166 cites W2751683279 @default.
- W3183669166 cites W2772358396 @default.
- W3183669166 cites W2781300578 @default.
- W3183669166 cites W2789118506 @default.
- W3183669166 cites W2793547752 @default.
- W3183669166 cites W2793848050 @default.
- W3183669166 cites W2795260874 @default.
- W3183669166 cites W2795472352 @default.
- W3183669166 cites W2802981758 @default.
- W3183669166 cites W2804653411 @default.
- W3183669166 cites W2805471158 @default.
- W3183669166 cites W2805682095 @default.
- W3183669166 cites W2808907024 @default.
- W3183669166 cites W2811409368 @default.
- W3183669166 cites W2883246692 @default.
- W3183669166 cites W2886103315 @default.
- W3183669166 cites W2887511045 @default.
- W3183669166 cites W2895881476 @default.
- W3183669166 cites W2898533848 @default.
- W3183669166 cites W2909685955 @default.
- W3183669166 cites W2917856159 @default.
- W3183669166 cites W2921533698 @default.
- W3183669166 cites W2922122210 @default.
- W3183669166 cites W2938918808 @default.
- W3183669166 cites W2955902092 @default.
- W3183669166 cites W2964084819 @default.
- W3183669166 cites W2966258649 @default.
- W3183669166 cites W2980094045 @default.
- W3183669166 cites W2990076749 @default.
- W3183669166 cites W2990510362 @default.
- W3183669166 cites W2997999874 @default.
- W3183669166 cites W3006608930 @default.
- W3183669166 cites W3007162068 @default.
- W3183669166 cites W3007527647 @default.
- W3183669166 cites W3008466937 @default.
- W3183669166 cites W3010825741 @default.
- W3183669166 cites W3020062944 @default.
- W3183669166 cites W3032099014 @default.
- W3183669166 cites W3033550936 @default.
- W3183669166 cites W3038078144 @default.
- W3183669166 cites W3039289988 @default.
- W3183669166 cites W3044870886 @default.
- W3183669166 cites W3084374992 @default.
- W3183669166 cites W3085631809 @default.
- W3183669166 cites W3085738785 @default.
- W3183669166 cites W3093004696 @default.
- W3183669166 cites W3094470232 @default.
- W3183669166 cites W3106974874 @default.
- W3183669166 cites W3108209790 @default.
- W3183669166 cites W3116812615 @default.
- W3183669166 cites W3160713245 @default.
- W3183669166 cites W4238510752 @default.
- W3183669166 cites W4249303092 @default.
- W3183669166 doi "https://doi.org/10.1002/adhm.202100633" @default.
- W3183669166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34292676" @default.
- W3183669166 hasPublicationYear "2021" @default.