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- W3183807991 abstract "Palladium catalysed addition of arylboronic acid to the readily available 2-cyano-(N-aryl)-acetamide or ethyl-2-cyanoacetate followed by subsequent reaction transform them into the biologically significant 4-arylquinolin-2-one or pyrazolone derivatives. The reaction conditions are robust enough to prevent the hydrolysis of ester/amide moiety during arylation. In addition, the unactivated nitrile moiety in the acetonitrile also converted to the corresponding acetophenone derivative." @default.
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- W3183807991 date "2021-08-01" @default.
- W3183807991 modified "2023-09-25" @default.
- W3183807991 title "Palladium catalysed hydrolysis-free arylation of aliphatic nitriles for the synthesis of 4-arylquinolin-2-one/pyrazolone derivatives" @default.
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- W3183807991 doi "https://doi.org/10.1016/j.tetlet.2021.153296" @default.
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