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- W3183962439 abstract "Rare sugars are regarded as functional biological materials due to their potential applications as low-calorie sweeteners, antioxidants, nucleoside analogs, and immunosuppressants. D -Allose is a rare sugar that has attracted substantial attention in recent years, owing to its pharmaceutical activities, but it is still not widely available. To address this limitation, we continuously produced D -allose from D -allulose using a packed bed reactor with commercial glucose isomerase (Sweetzyme IT). The optimal conditions for D -allose production were determined to be pH 8.0 and 60°C, with 500 g/L D -allulose as a substrate at a dilution rate of 0.24/h. Using these optimum conditions, the commercial glucose isomerase produced an average of 150 g/L D -allose over 20 days, with a productivity of 36 g/L/h and a conversion yield of 30%. This is the first report of the successful continuous production of D -allose from D -allulose by commercial glucose isomerase using a packed bed reactor, which can potentially provide a continuous production system for industrial applications of D -allose." @default.
- W3183962439 created "2021-08-02" @default.
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- W3183962439 date "2021-07-15" @default.
- W3183962439 modified "2023-10-17" @default.
- W3183962439 title "Production of D-Allose From D-Allulose Using Commercial Immobilized Glucose Isomerase" @default.
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- W3183962439 doi "https://doi.org/10.3389/fbioe.2021.681253" @default.
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