FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3184348531> ?p ?o ?g. }

• W3184348531 endingPage "e11806" @default.
• W3184348531 startingPage "e11806" @default.
• W3184348531 abstract "Turkey respiratory and gut microbiota play important roles in promoting health and production performance. Loss of microbiota homeostasis due to pathogen infection can worsen the disease or predispose the bird to infection by other pathogens. While turkeys are highly susceptible to influenza viruses of different origins, the impact of influenza virus infection on turkey gut and respiratory microbiota has not been demonstrated. In this study, we investigated the relationships between low pathogenicity avian influenza (LPAI) virus replication, cytokine gene expression, and respiratory and gut microbiota disruption in specific-pathogen-free turkeys. Differential replication of two LPAI H5N2 viruses paralleled the levels of clinical signs and cytokine gene expression. During active virus shedding, there was significant increase of ileal and nasal bacterial contents, which inversely corresponded with bacterial species diversity. Spearman’s correlation tests between bacterial abundance and local viral titers revealed that LPAI virus-induced dysbiosis was strongest in the nasal cavity followed by trachea, and weakest in the gut. Significant correlations were also observed between cytokine gene expression levels and relative abundances of several bacteria in tracheas of infected turkeys. For example, interferon γ/λ and interleukin-6 gene expression levels were correlated positively with Staphylococcus and Pseudomonas abundances, and negatively with Lactobacillus abundance. Overall, our data suggest a potential relationship where bacterial community diversity and enrichment or depletion of several bacterial genera in the gut and respiratory tract are dependent on the level of LPAI virus replication. Further work is needed to establish whether respiratory and enteric dysbiosis in LPAI virus-infected turkeys is a result of host immunological responses or other causes such as changes in nutritional uptake." @default.
• W3184348531 created "2021-08-02" @default.
• W3184348531 creator A5005716398 @default.
• W3184348531 creator A5025036502 @default.
• W3184348531 creator A5031530447 @default.
• W3184348531 creator A5048630488 @default.
• W3184348531 creator A5062165182 @default.
• W3184348531 creator A5072684159 @default.
• W3184348531 creator A5081088892 @default.
• W3184348531 date "2021-07-22" @default.
• W3184348531 modified "2023-09-27" @default.
• W3184348531 title "Influenza A virus infection in turkeys induces respiratory and enteric bacterial dysbiosis correlating with cytokine gene expression" @default.
• W3184348531 cites W1556060949 @default.
• W3184348531 cites W1841253029 @default.
• W3184348531 cites W1887107652 @default.
• W3184348531 cites W1969359874 @default.
• W3184348531 cites W1972340720 @default.
• W3184348531 cites W1985381347 @default.
• W3184348531 cites W1987567402 @default.
• W3184348531 cites W1994710883 @default.
• W3184348531 cites W1995744610 @default.
• W3184348531 cites W2012094117 @default.
• W3184348531 cites W2021701929 @default.
• W3184348531 cites W2021757305 @default.
• W3184348531 cites W2026690349 @default.
• W3184348531 cites W2038883884 @default.
• W3184348531 cites W2041912408 @default.
• W3184348531 cites W2046494066 @default.
• W3184348531 cites W2051031652 @default.
• W3184348531 cites W2079973992 @default.
• W3184348531 cites W2093935001 @default.
• W3184348531 cites W2102062324 @default.
• W3184348531 cites W2103332250 @default.
• W3184348531 cites W2106248075 @default.
• W3184348531 cites W2108150869 @default.
• W3184348531 cites W2117094580 @default.
• W3184348531 cites W2122061694 @default.
• W3184348531 cites W2123014057 @default.
• W3184348531 cites W2124429792 @default.
• W3184348531 cites W2125703277 @default.
• W3184348531 cites W2133016683 @default.
• W3184348531 cites W2133402546 @default.
• W3184348531 cites W2140212995 @default.
• W3184348531 cites W2141578380 @default.
• W3184348531 cites W2150648677 @default.
• W3184348531 cites W2157117253 @default.
• W3184348531 cites W2157174863 @default.
• W3184348531 cites W2166171121 @default.
• W3184348531 cites W2166358290 @default.
• W3184348531 cites W2171111233 @default.
• W3184348531 cites W2189034432 @default.
• W3184348531 cites W2279161330 @default.
• W3184348531 cites W2291125765 @default.
• W3184348531 cites W2294336544 @default.
• W3184348531 cites W2301738150 @default.
• W3184348531 cites W2327044638 @default.
• W3184348531 cites W2334160896 @default.
• W3184348531 cites W2341235511 @default.
• W3184348531 cites W2345507899 @default.
• W3184348531 cites W2402812416 @default.
• W3184348531 cites W2411336056 @default.
• W3184348531 cites W2416871996 @default.
• W3184348531 cites W2506843120 @default.
• W3184348531 cites W2550621976 @default.
• W3184348531 cites W2565420945 @default.
• W3184348531 cites W2585832663 @default.
• W3184348531 cites W2593868894 @default.
• W3184348531 cites W2605788558 @default.
• W3184348531 cites W2613076358 @default.
• W3184348531 cites W2718202718 @default.
• W3184348531 cites W2754062354 @default.
• W3184348531 cites W2771761853 @default.
• W3184348531 cites W2776494628 @default.
• W3184348531 cites W2783687920 @default.
• W3184348531 cites W2786585979 @default.
• W3184348531 cites W2792656513 @default.
• W3184348531 cites W2793972548 @default.
• W3184348531 cites W2795549399 @default.
• W3184348531 cites W2795940571 @default.
• W3184348531 cites W2800303837 @default.
• W3184348531 cites W2803998724 @default.
• W3184348531 cites W2805238146 @default.
• W3184348531 cites W2888812509 @default.
• W3184348531 cites W2897625780 @default.
• W3184348531 cites W2898017021 @default.
• W3184348531 cites W2901489236 @default.
• W3184348531 cites W2910890751 @default.
• W3184348531 cites W2912826408 @default.
• W3184348531 cites W2915365303 @default.
• W3184348531 cites W2915395634 @default.
• W3184348531 cites W2926360209 @default.
• W3184348531 cites W2944714515 @default.
• W3184348531 cites W2954104590 @default.
• W3184348531 cites W2963276645 @default.
• W3184348531 cites W2963305877 @default.
• W3184348531 cites W2965171603 @default.
• W3184348531 cites W2971758813 @default.
• W3184348531 cites W2982611833 @default.

• next