Matches in SemOpenAlex for { <https://semopenalex.org/work/W3184395280> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3184395280 endingPage "28" @default.
- W3184395280 startingPage "20" @default.
- W3184395280 abstract "Purpose . To identify major factors affecting the overall survival (OS). To select the cohort of patients with the best prognosis. Materials and methods . A retrospective analysis included data of 268 patients, 128 men and 140 women, with median age of 59±10,53 (30 to 83) years. For multivariate analysis of survival, patients were selected who underwent pancreaticoduodenectomy (PD) for ductal adenocarcinoma of the pancreatic head. Results . Our study demonstrated that histologically verified vascular invasion (detected only in 30 % of patients who underwent PD with resection of the major vessels) statistically significantly affected the OS. The increased CA19-9 level over 500 U / L (detected in 32,3 % of cases) is the factor that significantly worsens the OS. Patients with high grade adenocarcinoma have significantly better survival rates compared with patients who have moderately or poorly differentiated adenocarcinoma (p = 0.014; median 26 months, 95 % CI 4.4–47.6 versus median 17 months, 95 % CI 15–19, an median: 13 months, 95 % CI 5–21, respectively). Also, the use of adjuvant chemotherapy has a positive effect on long-term outcomes (p = 0.0001; median 26 months, 95 % CI 21.7–30.3 versus median 13 months, 95 % CI 11.3–14.7). Conclusion . A well-differentiated tumor and the use of adjuvant chemotherapy significantly increase the OS of patients. Poorly differentiated tumor, CA19-9 level over 500 U / mL and the histologically confirmed vascular invasion significantly worsen the prognosis of these patients." @default.
- W3184395280 created "2021-08-02" @default.
- W3184395280 creator A5007197573 @default.
- W3184395280 creator A5027780000 @default.
- W3184395280 creator A5028126278 @default.
- W3184395280 creator A5043843680 @default.
- W3184395280 date "2021-07-26" @default.
- W3184395280 modified "2023-10-17" @default.
- W3184395280 title "Factors affecting overall survival in ductal adenocarcinoma of the pancreatic head. Experience of one center" @default.
- W3184395280 cites W1990456502 @default.
- W3184395280 cites W2107780185 @default.
- W3184395280 cites W2620978696 @default.
- W3184395280 cites W2799575632 @default.
- W3184395280 cites W2919982348 @default.
- W3184395280 cites W2921197938 @default.
- W3184395280 doi "https://doi.org/10.18027/2224-5057-2021-11-1-20-28" @default.
- W3184395280 hasPublicationYear "2021" @default.
- W3184395280 type Work @default.
- W3184395280 sameAs 3184395280 @default.
- W3184395280 citedByCount "0" @default.
- W3184395280 crossrefType "journal-article" @default.
- W3184395280 hasAuthorship W3184395280A5007197573 @default.
- W3184395280 hasAuthorship W3184395280A5027780000 @default.
- W3184395280 hasAuthorship W3184395280A5028126278 @default.
- W3184395280 hasAuthorship W3184395280A5043843680 @default.
- W3184395280 hasBestOaLocation W31843952801 @default.
- W3184395280 hasConcept C121608353 @default.
- W3184395280 hasConcept C126322002 @default.
- W3184395280 hasConcept C141071460 @default.
- W3184395280 hasConcept C143998085 @default.
- W3184395280 hasConcept C167135981 @default.
- W3184395280 hasConcept C2776694085 @default.
- W3184395280 hasConcept C2778764654 @default.
- W3184395280 hasConcept C2778975757 @default.
- W3184395280 hasConcept C2780073493 @default.
- W3184395280 hasConcept C2780210213 @default.
- W3184395280 hasConcept C2781182431 @default.
- W3184395280 hasConcept C2992026798 @default.
- W3184395280 hasConcept C3018227240 @default.
- W3184395280 hasConcept C38180746 @default.
- W3184395280 hasConcept C50382708 @default.
- W3184395280 hasConcept C530470458 @default.
- W3184395280 hasConcept C71924100 @default.
- W3184395280 hasConcept C72563966 @default.
- W3184395280 hasConcept C90924648 @default.
- W3184395280 hasConceptScore W3184395280C121608353 @default.
- W3184395280 hasConceptScore W3184395280C126322002 @default.
- W3184395280 hasConceptScore W3184395280C141071460 @default.
- W3184395280 hasConceptScore W3184395280C143998085 @default.
- W3184395280 hasConceptScore W3184395280C167135981 @default.
- W3184395280 hasConceptScore W3184395280C2776694085 @default.
- W3184395280 hasConceptScore W3184395280C2778764654 @default.
- W3184395280 hasConceptScore W3184395280C2778975757 @default.
- W3184395280 hasConceptScore W3184395280C2780073493 @default.
- W3184395280 hasConceptScore W3184395280C2780210213 @default.
- W3184395280 hasConceptScore W3184395280C2781182431 @default.
- W3184395280 hasConceptScore W3184395280C2992026798 @default.
- W3184395280 hasConceptScore W3184395280C3018227240 @default.
- W3184395280 hasConceptScore W3184395280C38180746 @default.
- W3184395280 hasConceptScore W3184395280C50382708 @default.
- W3184395280 hasConceptScore W3184395280C530470458 @default.
- W3184395280 hasConceptScore W3184395280C71924100 @default.
- W3184395280 hasConceptScore W3184395280C72563966 @default.
- W3184395280 hasConceptScore W3184395280C90924648 @default.
- W3184395280 hasIssue "1" @default.
- W3184395280 hasLocation W31843952801 @default.
- W3184395280 hasOpenAccess W3184395280 @default.
- W3184395280 hasPrimaryLocation W31843952801 @default.
- W3184395280 hasRelatedWork W2096749239 @default.
- W3184395280 hasRelatedWork W2361700749 @default.
- W3184395280 hasRelatedWork W2381345080 @default.
- W3184395280 hasRelatedWork W2901344755 @default.
- W3184395280 hasRelatedWork W2911294724 @default.
- W3184395280 hasRelatedWork W4214517713 @default.
- W3184395280 hasRelatedWork W4291608089 @default.
- W3184395280 hasRelatedWork W4292448967 @default.
- W3184395280 hasRelatedWork W4305082178 @default.
- W3184395280 hasRelatedWork W4353081534 @default.
- W3184395280 hasVolume "11" @default.
- W3184395280 isParatext "false" @default.
- W3184395280 isRetracted "false" @default.
- W3184395280 magId "3184395280" @default.
- W3184395280 workType "article" @default.