Matches in SemOpenAlex for { <https://semopenalex.org/work/W3184683246> ?p ?o ?g. }
- W3184683246 endingPage "624" @default.
- W3184683246 startingPage "613" @default.
- W3184683246 abstract "Serum can be used to investigate changes in cytokine concentration following burn injury in children; however, for children receiving treatment in an outpatient setting, blood is not routinely collected and therefore cannot be used for monitoring. The aim of this study was to investigate the use of saliva as a noninvasive tool for predicting burn outcomes by measuring the concentration of salivary cytokines in children with small area burns. A multiplex cytokine assay was used to measure 17 cytokines in the saliva of pediatric patients with burns (n = 20) and healthy controls (n = 20). After the removal of cytokines that had >30% of samples below the assay lower detection limit, six cytokines including IL-1β, IL-4, IL-7, IL-8, MCP-1, and TNFα were analyzed for association with burns. IL-1β and IL-4 were found to be significantly elevated in the pediatric burn patients compared to healthy controls. Interestingly, IL-1β was also significantly elevated in scald burns, compared to contact burns. In addition, biologically meaningful differences in cytokine concentration were identified in patients with different burn characteristics, which warrant further investigation. This exploratory study provides evidence that cytokines can be detected in the saliva of children and that salivary cytokine profiles differ between healthy controls and children with burns. Overall, this study demonstrates the value of saliva for the investigation of cytokines and its potential application in pediatric diagnostics, specifically in situations where blood collection is not appropriate." @default.
- W3184683246 created "2021-08-02" @default.
- W3184683246 creator A5010879671 @default.
- W3184683246 creator A5018634675 @default.
- W3184683246 creator A5035276230 @default.
- W3184683246 creator A5035406666 @default.
- W3184683246 creator A5076267305 @default.
- W3184683246 creator A5085095019 @default.
- W3184683246 date "2021-07-29" @default.
- W3184683246 modified "2023-09-25" @default.
- W3184683246 title "An Exploratory Study Demonstrating That Salivary Cytokine Profiles Are Altered in Children With Small Area Thermal Injury" @default.
- W3184683246 cites W136985941 @default.
- W3184683246 cites W14553783 @default.
- W3184683246 cites W1600480105 @default.
- W3184683246 cites W1967052290 @default.
- W3184683246 cites W1983984331 @default.
- W3184683246 cites W1985859647 @default.
- W3184683246 cites W1992396801 @default.
- W3184683246 cites W1997028691 @default.
- W3184683246 cites W2020314628 @default.
- W3184683246 cites W2025802167 @default.
- W3184683246 cites W2030015146 @default.
- W3184683246 cites W2038145435 @default.
- W3184683246 cites W2048027223 @default.
- W3184683246 cites W2052230840 @default.
- W3184683246 cites W2077107023 @default.
- W3184683246 cites W2103782947 @default.
- W3184683246 cites W2114140542 @default.
- W3184683246 cites W2133569121 @default.
- W3184683246 cites W2591065649 @default.
- W3184683246 cites W2593237222 @default.
- W3184683246 cites W2595335124 @default.
- W3184683246 cites W2742164043 @default.
- W3184683246 cites W2751757703 @default.
- W3184683246 cites W2763185920 @default.
- W3184683246 cites W2763791222 @default.
- W3184683246 cites W2766910604 @default.
- W3184683246 cites W2767992854 @default.
- W3184683246 cites W2831206472 @default.
- W3184683246 cites W2883303286 @default.
- W3184683246 cites W2884313747 @default.
- W3184683246 cites W2921721459 @default.
- W3184683246 cites W2927420473 @default.
- W3184683246 cites W2998226062 @default.
- W3184683246 cites W3006962407 @default.
- W3184683246 cites W3011793430 @default.
- W3184683246 cites W3109235901 @default.
- W3184683246 cites W3128197868 @default.
- W3184683246 cites W4242429447 @default.
- W3184683246 cites W4376453100 @default.
- W3184683246 cites W46876298 @default.
- W3184683246 doi "https://doi.org/10.1093/jbcr/irab147" @default.
- W3184683246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34323997" @default.
- W3184683246 hasPublicationYear "2021" @default.
- W3184683246 type Work @default.
- W3184683246 sameAs 3184683246 @default.
- W3184683246 citedByCount "2" @default.
- W3184683246 countsByYear W31846832462022 @default.
- W3184683246 countsByYear W31846832462023 @default.
- W3184683246 crossrefType "journal-article" @default.
- W3184683246 hasAuthorship W3184683246A5010879671 @default.
- W3184683246 hasAuthorship W3184683246A5018634675 @default.
- W3184683246 hasAuthorship W3184683246A5035276230 @default.
- W3184683246 hasAuthorship W3184683246A5035406666 @default.
- W3184683246 hasAuthorship W3184683246A5076267305 @default.
- W3184683246 hasAuthorship W3184683246A5085095019 @default.
- W3184683246 hasBestOaLocation W31846832462 @default.
- W3184683246 hasConcept C126322002 @default.
- W3184683246 hasConcept C141071460 @default.
- W3184683246 hasConcept C142724271 @default.
- W3184683246 hasConcept C203014093 @default.
- W3184683246 hasConcept C2776782833 @default.
- W3184683246 hasConcept C2778690821 @default.
- W3184683246 hasConcept C2781257246 @default.
- W3184683246 hasConcept C2988731192 @default.
- W3184683246 hasConcept C2993242423 @default.
- W3184683246 hasConcept C504460877 @default.
- W3184683246 hasConcept C71924100 @default.
- W3184683246 hasConceptScore W3184683246C126322002 @default.
- W3184683246 hasConceptScore W3184683246C141071460 @default.
- W3184683246 hasConceptScore W3184683246C142724271 @default.
- W3184683246 hasConceptScore W3184683246C203014093 @default.
- W3184683246 hasConceptScore W3184683246C2776782833 @default.
- W3184683246 hasConceptScore W3184683246C2778690821 @default.
- W3184683246 hasConceptScore W3184683246C2781257246 @default.
- W3184683246 hasConceptScore W3184683246C2988731192 @default.
- W3184683246 hasConceptScore W3184683246C2993242423 @default.
- W3184683246 hasConceptScore W3184683246C504460877 @default.
- W3184683246 hasConceptScore W3184683246C71924100 @default.
- W3184683246 hasFunder F4320315885 @default.
- W3184683246 hasFunder F4320320501 @default.
- W3184683246 hasFunder F4320320983 @default.
- W3184683246 hasFunder F4320332161 @default.
- W3184683246 hasFunder F4320334705 @default.
- W3184683246 hasIssue "3" @default.
- W3184683246 hasLocation W31846832461 @default.
- W3184683246 hasLocation W31846832462 @default.
- W3184683246 hasLocation W31846832463 @default.