FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3184832113> ?p ?o ?g. }

• W3184832113 endingPage "2294" @default.
• W3184832113 startingPage "2285" @default.
• W3184832113 abstract "Abstract In a recent issue of Clinical Kidney Journal (CKJ), Gutierrez-Peña et al. reported a high incidence and prevalence of advanced chronic kidney disease (CKD) in Aguascalientes, Mexico. This contradicts Global Burden of Disease estimates, which should be updated. A key component of this high burden of CKD relates to young people ages 20–40 years in whom the cause of CKD was unknown [CKD of unknown aetiology (CKDu)]. The incidence of kidney replacement therapy in this age group in Aguascalientes is among the highest in the world, second only to Taiwan. However, high-altitude Aguascalientes, with a year-round average temperature of 19°C, does not fit the geography of other CKDu hotspots. Furthermore, kidney biopsies in young people showed a high prevalence of focal segmental glomerulosclerosis. Potential causes of CKDu in Aguascalientes include the genetic background (no evidence, although podocytopathy genes should be explored) and environmental factors. The highest prevalence of CKD was found in Calvillo, known for guava farming. Thus guava itself, known to contain bioactive, potentially nephrotoxic molecules and pesticides, should be explored. Additionally, there are reports of water sources in Aguascalientes contaminated with heavy metals and/or pesticides. These include fluoride (increased levels found in Calvillo drinking water) as well as naturally occurring arsenic, among others. Fluoride may accumulate in bone and cause kidney disease years later, and maternal exposure to excess fluoride may cause kidney disease in offspring. We propose a research agenda to clarify the cause of CKDu in Aguascalientes that should involve international funders. The need for urgent action to identify and stem the cause of the high incidence of CKD extends to other CKD hotspots in Mexico, including Tierra Blanca in Veracruz and Poncitlan in Jalisco." @default.
• W3184832113 created "2021-08-02" @default.
• W3184832113 creator A5000392575 @default.
• W3184832113 creator A5036264468 @default.
• W3184832113 creator A5061562707 @default.
• W3184832113 creator A5063245254 @default.
• W3184832113 date "2021-07-15" @default.
• W3184832113 modified "2023-10-17" @default.
• W3184832113 title "Aguascalientes: one of the hottest chronic kidney disease (CKD) hotspots in Mexico and a CKD of unknown aetiology mystery to be solved" @default.
• W3184832113 cites W1854028905 @default.
• W3184832113 cites W1969690599 @default.
• W3184832113 cites W1973462203 @default.
• W3184832113 cites W1981416675 @default.
• W3184832113 cites W1983752167 @default.
• W3184832113 cites W1990956714 @default.
• W3184832113 cites W2001526173 @default.
• W3184832113 cites W2005980936 @default.
• W3184832113 cites W2009132304 @default.
• W3184832113 cites W2012034410 @default.
• W3184832113 cites W2018844943 @default.
• W3184832113 cites W2034247812 @default.
• W3184832113 cites W2043748189 @default.
• W3184832113 cites W2045655949 @default.
• W3184832113 cites W2048779286 @default.
• W3184832113 cites W2068806064 @default.
• W3184832113 cites W2089920736 @default.
• W3184832113 cites W2109117342 @default.
• W3184832113 cites W2141947091 @default.
• W3184832113 cites W2177863210 @default.
• W3184832113 cites W2578376389 @default.
• W3184832113 cites W2588171859 @default.
• W3184832113 cites W2609728913 @default.
• W3184832113 cites W2774670497 @default.
• W3184832113 cites W2782582227 @default.
• W3184832113 cites W2790423557 @default.
• W3184832113 cites W2790629960 @default.
• W3184832113 cites W2794405759 @default.
• W3184832113 cites W2808224695 @default.
• W3184832113 cites W2886565306 @default.
• W3184832113 cites W2901335962 @default.
• W3184832113 cites W2972604213 @default.
• W3184832113 cites W2981562581 @default.
• W3184832113 cites W2996294381 @default.
• W3184832113 cites W3014088225 @default.
• W3184832113 cites W3019966725 @default.
• W3184832113 cites W3021986985 @default.
• W3184832113 cites W3027035827 @default.
• W3184832113 cites W3029616576 @default.
• W3184832113 cites W3033794056 @default.
• W3184832113 cites W3081891764 @default.
• W3184832113 cites W3082080695 @default.
• W3184832113 cites W3111505690 @default.
• W3184832113 cites W3115634213 @default.
• W3184832113 cites W3125513064 @default.
• W3184832113 doi "https://doi.org/10.1093/ckj/sfab136" @default.
• W3184832113 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8573004" @default.
• W3184832113 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34754425" @default.
• W3184832113 hasPublicationYear "2021" @default.
• W3184832113 type Work @default.
• W3184832113 sameAs 3184832113 @default.
• W3184832113 citedByCount "9" @default.
• W3184832113 countsByYear W31848321132022 @default.
• W3184832113 countsByYear W31848321132023 @default.
• W3184832113 crossrefType "journal-article" @default.
• W3184832113 hasAuthorship W3184832113A5000392575 @default.
• W3184832113 hasAuthorship W3184832113A5036264468 @default.
• W3184832113 hasAuthorship W3184832113A5061562707 @default.
• W3184832113 hasAuthorship W3184832113A5063245254 @default.
• W3184832113 hasBestOaLocation W31848321131 @default.
• W3184832113 hasConcept C120665830 @default.
• W3184832113 hasConcept C121332964 @default.
• W3184832113 hasConcept C126322002 @default.
• W3184832113 hasConcept C137627325 @default.
• W3184832113 hasConcept C2778653478 @default.
• W3184832113 hasConcept C2779134260 @default.
• W3184832113 hasConcept C61511704 @default.
• W3184832113 hasConcept C71924100 @default.
• W3184832113 hasConcept C99454951 @default.
• W3184832113 hasConceptScore W3184832113C120665830 @default.
• W3184832113 hasConceptScore W3184832113C121332964 @default.
• W3184832113 hasConceptScore W3184832113C126322002 @default.
• W3184832113 hasConceptScore W3184832113C137627325 @default.
• W3184832113 hasConceptScore W3184832113C2778653478 @default.
• W3184832113 hasConceptScore W3184832113C2779134260 @default.
• W3184832113 hasConceptScore W3184832113C61511704 @default.
• W3184832113 hasConceptScore W3184832113C71924100 @default.
• W3184832113 hasConceptScore W3184832113C99454951 @default.
• W3184832113 hasIssue "11" @default.
• W3184832113 hasLocation W31848321131 @default.
• W3184832113 hasLocation W31848321132 @default.
• W3184832113 hasLocation W31848321133 @default.
• W3184832113 hasLocation W31848321134 @default.
• W3184832113 hasOpenAccess W3184832113 @default.
• W3184832113 hasPrimaryLocation W31848321131 @default.
• W3184832113 hasRelatedWork W1970383787 @default.
• W3184832113 hasRelatedWork W2001168913 @default.
• W3184832113 hasRelatedWork W2008908422 @default.
• W3184832113 hasRelatedWork W2112172095 @default.

• next