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- W3184969439 abstract "Desmoid-type fibromatosis (DF) is a rare tumor that develops in the limbs, abdominal wall, and abdominal cavity. It is accounting for less than 3% of soft-tissue sarcomas and less than 0.03% of all neoplasms. A 57-year-old man was diagnosed as acute peritonitis due to intra-abdominal tumor rupture. Since his systematic symptoms were relatively stable, gastrointestinal perforation was ruled out, the differential diagnosis of the tumor itself was difficult, and it was unclear resectable by emergency surgery, we started conservative treatment. After examinations, ileocolectomy was performed. Histopathological examination revealed spindle cells with collagenous fiber hyperplasia and immunohistochemical staining for β-catenin was positive, so we made a diagnosis of mesenteric desmoid-type fibromatosis (MDF). The mechanism of DF development is suggested to be associated with hereditary diseases, mechanical stimuli, and a history of exposure to radiation appear to be involved as pathogenetic factors in sporadic development. Surgical resection is the first-line treatment for MDF, but the postoperative high local recurrence rate is problematic. Drug therapy and radiation therapy are selected for cases in which radical resection is not possible or for recurrent cases. However, the number of examined cases is small and sufficient evidence has not been accumulated for most treatment strategies, it is expected that the optimal treatment at the time of recurrence will be further verified by the accumulation of MDF. There are few reports of peritonitis caused by MDF rupture; emergency surgery can be avoided." @default.
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- W3184969439 date "2021-08-01" @default.
- W3184969439 modified "2023-10-03" @default.
- W3184969439 title "Ruptured mesenteric desmoid-type fibromatosis without emergency surgery: A rare case report" @default.
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- W3184969439 doi "https://doi.org/10.1016/j.ijscr.2021.106208" @default.
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