Matches in SemOpenAlex for { <https://semopenalex.org/work/W3185157095> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W3185157095 endingPage "559" @default.
- W3185157095 startingPage "553" @default.
- W3185157095 abstract "ABSTRACT: Background: There is international variability in whether neurological determination of death (NDD) is conceptually defined based on permanent loss of brainstem function or “whole brain death.” Canadian guidelines are not definitive. Patients with infratentorial stroke may meet clinical criteria for NDD despite persistent cerebral blood flow (CBF) and relative absence of supratentorial injury. Methods: We performed a multicenter cohort study involving patients that died from ischemic or hemorrhagic stroke in Alberta intensive care units from 2013 to 2019, focusing on those with infratentorial involvement. Medical records were reviewed to determine the incidence and proportion of patients that met clinical criteria for NDD; whether ancillary testing was performed; and if so, whether this demonstrated the absence of CBF. Results: There were 95 (27%) deaths from infratentorial and 263 (73%) from supratentorial stroke. Sixteen patients (17%) with infratentorial stroke had neurological examination consistent with NDD (0.55 cases per million per year). Among patients that underwent confirmatory evaluation for NDD with an apnea test, ancillary test (radionuclide scan), or both, ancillary testing was more common with infratentorial compared with supratentorial stroke (10/12 (85%) vs. 25/47 (53%), p = 0.04). Persistent CBF was detected in 6/10 (60%) patients with infratentorial compared with 0/25 with supratentorial stroke ( p = 0.0001). Conclusions: Infratentorial stroke leading to clinical criteria for NDD occurs with an annual incidence of about 0.55 per million. There is variability in clinicians’ use of ancillary testing. Persistent CBF was detected in more than half of patients that underwent radionuclide scans. Canadian consensus is needed to guide clinical practice." @default.
- W3185157095 created "2021-08-02" @default.
- W3185157095 creator A5003074300 @default.
- W3185157095 creator A5008303654 @default.
- W3185157095 creator A5032053468 @default.
- W3185157095 creator A5048893068 @default.
- W3185157095 creator A5052459990 @default.
- W3185157095 date "2021-07-22" @default.
- W3185157095 modified "2023-10-12" @default.
- W3185157095 title "Neurological Determination of Death Following Infratentorial Stroke: A Population-Based Cohort Study" @default.
- W3185157095 cites W1637758957 @default.
- W3185157095 cites W2117417171 @default.
- W3185157095 cites W2123762629 @default.
- W3185157095 cites W2143906500 @default.
- W3185157095 cites W2738329935 @default.
- W3185157095 cites W2750183570 @default.
- W3185157095 cites W2889053532 @default.
- W3185157095 cites W2895676484 @default.
- W3185157095 cites W2904160100 @default.
- W3185157095 cites W2943664581 @default.
- W3185157095 cites W2953376445 @default.
- W3185157095 cites W2955728019 @default.
- W3185157095 cites W3047035166 @default.
- W3185157095 doi "https://doi.org/10.1017/cjn.2021.177" @default.
- W3185157095 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34289929" @default.
- W3185157095 hasPublicationYear "2021" @default.
- W3185157095 type Work @default.
- W3185157095 sameAs 3185157095 @default.
- W3185157095 citedByCount "6" @default.
- W3185157095 countsByYear W31851570952022 @default.
- W3185157095 countsByYear W31851570952023 @default.
- W3185157095 crossrefType "journal-article" @default.
- W3185157095 hasAuthorship W3185157095A5003074300 @default.
- W3185157095 hasAuthorship W3185157095A5008303654 @default.
- W3185157095 hasAuthorship W3185157095A5032053468 @default.
- W3185157095 hasAuthorship W3185157095A5048893068 @default.
- W3185157095 hasAuthorship W3185157095A5052459990 @default.
- W3185157095 hasBestOaLocation W31851570951 @default.
- W3185157095 hasConcept C120665830 @default.
- W3185157095 hasConcept C121332964 @default.
- W3185157095 hasConcept C126322002 @default.
- W3185157095 hasConcept C127413603 @default.
- W3185157095 hasConcept C141071460 @default.
- W3185157095 hasConcept C187212893 @default.
- W3185157095 hasConcept C194828623 @default.
- W3185157095 hasConcept C201903717 @default.
- W3185157095 hasConcept C2780168130 @default.
- W3185157095 hasConcept C2780645631 @default.
- W3185157095 hasConcept C2908647359 @default.
- W3185157095 hasConcept C61511704 @default.
- W3185157095 hasConcept C71924100 @default.
- W3185157095 hasConcept C72563966 @default.
- W3185157095 hasConcept C78519656 @default.
- W3185157095 hasConcept C99454951 @default.
- W3185157095 hasConceptScore W3185157095C120665830 @default.
- W3185157095 hasConceptScore W3185157095C121332964 @default.
- W3185157095 hasConceptScore W3185157095C126322002 @default.
- W3185157095 hasConceptScore W3185157095C127413603 @default.
- W3185157095 hasConceptScore W3185157095C141071460 @default.
- W3185157095 hasConceptScore W3185157095C187212893 @default.
- W3185157095 hasConceptScore W3185157095C194828623 @default.
- W3185157095 hasConceptScore W3185157095C201903717 @default.
- W3185157095 hasConceptScore W3185157095C2780168130 @default.
- W3185157095 hasConceptScore W3185157095C2780645631 @default.
- W3185157095 hasConceptScore W3185157095C2908647359 @default.
- W3185157095 hasConceptScore W3185157095C61511704 @default.
- W3185157095 hasConceptScore W3185157095C71924100 @default.
- W3185157095 hasConceptScore W3185157095C72563966 @default.
- W3185157095 hasConceptScore W3185157095C78519656 @default.
- W3185157095 hasConceptScore W3185157095C99454951 @default.
- W3185157095 hasIssue "4" @default.
- W3185157095 hasLocation W31851570951 @default.
- W3185157095 hasLocation W31851570952 @default.
- W3185157095 hasOpenAccess W3185157095 @default.
- W3185157095 hasPrimaryLocation W31851570951 @default.
- W3185157095 hasRelatedWork W1606496894 @default.
- W3185157095 hasRelatedWork W2019060938 @default.
- W3185157095 hasRelatedWork W2103425699 @default.
- W3185157095 hasRelatedWork W2148718224 @default.
- W3185157095 hasRelatedWork W2330453918 @default.
- W3185157095 hasRelatedWork W2805271636 @default.
- W3185157095 hasRelatedWork W2961644586 @default.
- W3185157095 hasRelatedWork W3081332639 @default.
- W3185157095 hasRelatedWork W3152027859 @default.
- W3185157095 hasRelatedWork W1907635651 @default.
- W3185157095 hasVolume "49" @default.
- W3185157095 isParatext "false" @default.
- W3185157095 isRetracted "false" @default.
- W3185157095 magId "3185157095" @default.
- W3185157095 workType "article" @default.