FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3185179815> ?p ?o ?g. }

• W3185179815 endingPage "11" @default.
• W3185179815 startingPage "1" @default.
• W3185179815 abstract "Protocatechualdehyde (PCA), an important component of Salvia miltiorrhiza, has many activities, such as anti-inflammatory and antisepsis activities. However, the role of PCA in osteoclasts is not clear. We used RAW264.7 cells (a mouse leukemic monocyte/macrophage cell line) and bone marrow macrophages (BMMs) to probe the role of PCA in osteoclasts and the underlying mechanism. The effects of PCA on cell activity were evaluated with CCK-8 assays. TRAP staining detected mature osteoclasts. Corning Osteo Assay Surface plates were used to examine absorption. The levels of RNA and protein were analyzed, respectively, using RT-PCR and Western blotting. PCA (5 μg/ml) was not toxic to the two cell types but reduced the formation of osteoclasts and bone absorption. Furthermore, PCA restrained the expression of mRNAs encoding proteins associated with osteoclasts and reduced the phosphorylation of proteins in important signaling pathways. The results indicate that PCA inhibits osteoclast differentiation by suppressing NF-κB and MAPK activity." @default.
• W3185179815 created "2021-08-02" @default.
• W3185179815 creator A5000979147 @default.
• W3185179815 creator A5004923438 @default.
• W3185179815 creator A5021687717 @default.
• W3185179815 creator A5033647367 @default.
• W3185179815 creator A5045261192 @default.
• W3185179815 creator A5056923910 @default.
• W3185179815 date "2021-07-16" @default.
• W3185179815 modified "2023-10-16" @default.
• W3185179815 title "Protocatechualdehyde Inhibits the Osteoclast Differentiation of RAW264.7 and BMM Cells by Regulating NF-κB and MAPK Activity" @default.
• W3185179815 cites W1574748094 @default.
• W3185179815 cites W1972011046 @default.
• W3185179815 cites W1974059464 @default.
• W3185179815 cites W1975402260 @default.
• W3185179815 cites W1981922352 @default.
• W3185179815 cites W1982100025 @default.
• W3185179815 cites W1998538905 @default.
• W3185179815 cites W2004758487 @default.
• W3185179815 cites W2007417944 @default.
• W3185179815 cites W2077130844 @default.
• W3185179815 cites W2102411539 @default.
• W3185179815 cites W2159172969 @default.
• W3185179815 cites W2174832515 @default.
• W3185179815 cites W2190424893 @default.
• W3185179815 cites W2194825845 @default.
• W3185179815 cites W2328859367 @default.
• W3185179815 cites W2405381679 @default.
• W3185179815 cites W2416584938 @default.
• W3185179815 cites W2466995261 @default.
• W3185179815 cites W2472501679 @default.
• W3185179815 cites W2547535920 @default.
• W3185179815 cites W2781021584 @default.
• W3185179815 cites W2793648724 @default.
• W3185179815 cites W2884802080 @default.
• W3185179815 cites W2902737779 @default.
• W3185179815 cites W2940610969 @default.
• W3185179815 cites W2950956759 @default.
• W3185179815 cites W2967109547 @default.
• W3185179815 doi "https://doi.org/10.1155/2021/6108999" @default.
• W3185179815 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8302381" @default.
• W3185179815 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34327232" @default.
• W3185179815 hasPublicationYear "2021" @default.
• W3185179815 type Work @default.
• W3185179815 sameAs 3185179815 @default.
• W3185179815 citedByCount "3" @default.
• W3185179815 countsByYear W31851798152022 @default.
• W3185179815 countsByYear W31851798152023 @default.
• W3185179815 crossrefType "journal-article" @default.
• W3185179815 hasAuthorship W3185179815A5000979147 @default.
• W3185179815 hasAuthorship W3185179815A5004923438 @default.
• W3185179815 hasAuthorship W3185179815A5021687717 @default.
• W3185179815 hasAuthorship W3185179815A5033647367 @default.
• W3185179815 hasAuthorship W3185179815A5045261192 @default.
• W3185179815 hasAuthorship W3185179815A5056923910 @default.
• W3185179815 hasBestOaLocation W31851798151 @default.
• W3185179815 hasConcept C104317684 @default.
• W3185179815 hasConcept C11960822 @default.
• W3185179815 hasConcept C142724271 @default.
• W3185179815 hasConcept C1491633281 @default.
• W3185179815 hasConcept C153911025 @default.
• W3185179815 hasConcept C170493617 @default.
• W3185179815 hasConcept C185592680 @default.
• W3185179815 hasConcept C188947578 @default.
• W3185179815 hasConcept C202751555 @default.
• W3185179815 hasConcept C203014093 @default.
• W3185179815 hasConcept C204787440 @default.
• W3185179815 hasConcept C2776033226 @default.
• W3185179815 hasConcept C2776332195 @default.
• W3185179815 hasConcept C2779244956 @default.
• W3185179815 hasConcept C2781184567 @default.
• W3185179815 hasConcept C55493867 @default.
• W3185179815 hasConcept C57074206 @default.
• W3185179815 hasConcept C71924100 @default.
• W3185179815 hasConcept C85265743 @default.
• W3185179815 hasConcept C86803240 @default.
• W3185179815 hasConcept C95444343 @default.
• W3185179815 hasConceptScore W3185179815C104317684 @default.
• W3185179815 hasConceptScore W3185179815C11960822 @default.
• W3185179815 hasConceptScore W3185179815C142724271 @default.
• W3185179815 hasConceptScore W3185179815C1491633281 @default.
• W3185179815 hasConceptScore W3185179815C153911025 @default.
• W3185179815 hasConceptScore W3185179815C170493617 @default.
• W3185179815 hasConceptScore W3185179815C185592680 @default.
• W3185179815 hasConceptScore W3185179815C188947578 @default.
• W3185179815 hasConceptScore W3185179815C202751555 @default.
• W3185179815 hasConceptScore W3185179815C203014093 @default.
• W3185179815 hasConceptScore W3185179815C204787440 @default.
• W3185179815 hasConceptScore W3185179815C2776033226 @default.
• W3185179815 hasConceptScore W3185179815C2776332195 @default.
• W3185179815 hasConceptScore W3185179815C2779244956 @default.
• W3185179815 hasConceptScore W3185179815C2781184567 @default.
• W3185179815 hasConceptScore W3185179815C55493867 @default.
• W3185179815 hasConceptScore W3185179815C57074206 @default.
• W3185179815 hasConceptScore W3185179815C71924100 @default.
• W3185179815 hasConceptScore W3185179815C85265743 @default.
• W3185179815 hasConceptScore W3185179815C86803240 @default.
• W3185179815 hasConceptScore W3185179815C95444343 @default.

• next