Matches in SemOpenAlex for { <https://semopenalex.org/work/W3185450136> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W3185450136 endingPage "681" @default.
- W3185450136 startingPage "681" @default.
- W3185450136 abstract "Chemotherapy-induced neutropenia (CIN) has been associated with a risk of infections and chemotherapy dose reductions and delays. The chemotherapy regimen remains one of the primary determinants of the risk of neutropenia, with some regimens being more myelotoxic than others. Although a number of clinical trials have currently highlighted the risk of CIN with each chemotherapy regimen, only a few ones have comprehensively examined the risk associated with all chemotherapeutic agents. Therefore, this study aimed to investigate the risk factors and characteristics of CIN caused by each neoplastic agent using data from the large voluntary reporting Food and Drug Administration Adverse Event Reporting System database. Initially, univariate analysis showed that an age ≥ 65 years, the female sex, and treatment with chemotherapeutic agents were factors that caused CIN. Then, cluster and component analyses showed that cytotoxic agents (i.e., alkylating agents, antimetabolic agents, antineoplastic antibiotics, platinating agents, and plant-derived alkaloids) were associated with infection following neutropenia. This comprehensive analysis comparing CIN risk suggests that elderly or underweight patients treated with cytotoxic drugs require particularly careful monitoring." @default.
- W3185450136 created "2021-08-02" @default.
- W3185450136 creator A5015213436 @default.
- W3185450136 creator A5057190375 @default.
- W3185450136 creator A5071965046 @default.
- W3185450136 creator A5079504645 @default.
- W3185450136 creator A5090801808 @default.
- W3185450136 date "2021-07-15" @default.
- W3185450136 modified "2023-10-18" @default.
- W3185450136 title "Comprehensive Analysis of Chemotherapeutic Agents That Induce Infectious Neutropenia" @default.
- W3185450136 cites W1052654287 @default.
- W3185450136 cites W1546909751 @default.
- W3185450136 cites W1601865818 @default.
- W3185450136 cites W1648100333 @default.
- W3185450136 cites W1966449123 @default.
- W3185450136 cites W1981963681 @default.
- W3185450136 cites W1997799955 @default.
- W3185450136 cites W2031497779 @default.
- W3185450136 cites W2059287796 @default.
- W3185450136 cites W2064716383 @default.
- W3185450136 cites W2116899930 @default.
- W3185450136 cites W2124709079 @default.
- W3185450136 cites W2290950904 @default.
- W3185450136 cites W2550041748 @default.
- W3185450136 cites W2588368367 @default.
- W3185450136 cites W261240404 @default.
- W3185450136 cites W2788691011 @default.
- W3185450136 cites W2794626468 @default.
- W3185450136 cites W2801136696 @default.
- W3185450136 cites W2900713360 @default.
- W3185450136 cites W3111114071 @default.
- W3185450136 cites W3155585913 @default.
- W3185450136 cites W3159307090 @default.
- W3185450136 cites W4246513070 @default.
- W3185450136 cites W4254849975 @default.
- W3185450136 doi "https://doi.org/10.3390/ph14070681" @default.
- W3185450136 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8308812" @default.
- W3185450136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34358105" @default.
- W3185450136 hasPublicationYear "2021" @default.
- W3185450136 type Work @default.
- W3185450136 sameAs 3185450136 @default.
- W3185450136 citedByCount "10" @default.
- W3185450136 countsByYear W31854501362021 @default.
- W3185450136 countsByYear W31854501362022 @default.
- W3185450136 countsByYear W31854501362023 @default.
- W3185450136 crossrefType "journal-article" @default.
- W3185450136 hasAuthorship W3185450136A5015213436 @default.
- W3185450136 hasAuthorship W3185450136A5057190375 @default.
- W3185450136 hasAuthorship W3185450136A5071965046 @default.
- W3185450136 hasAuthorship W3185450136A5079504645 @default.
- W3185450136 hasAuthorship W3185450136A5090801808 @default.
- W3185450136 hasBestOaLocation W31854501361 @default.
- W3185450136 hasConcept C126322002 @default.
- W3185450136 hasConcept C143998085 @default.
- W3185450136 hasConcept C177713679 @default.
- W3185450136 hasConcept C197934379 @default.
- W3185450136 hasConcept C2776694085 @default.
- W3185450136 hasConcept C2777063308 @default.
- W3185450136 hasConcept C2780035454 @default.
- W3185450136 hasConcept C2781413609 @default.
- W3185450136 hasConcept C71924100 @default.
- W3185450136 hasConcept C98274493 @default.
- W3185450136 hasConceptScore W3185450136C126322002 @default.
- W3185450136 hasConceptScore W3185450136C143998085 @default.
- W3185450136 hasConceptScore W3185450136C177713679 @default.
- W3185450136 hasConceptScore W3185450136C197934379 @default.
- W3185450136 hasConceptScore W3185450136C2776694085 @default.
- W3185450136 hasConceptScore W3185450136C2777063308 @default.
- W3185450136 hasConceptScore W3185450136C2780035454 @default.
- W3185450136 hasConceptScore W3185450136C2781413609 @default.
- W3185450136 hasConceptScore W3185450136C71924100 @default.
- W3185450136 hasConceptScore W3185450136C98274493 @default.
- W3185450136 hasIssue "7" @default.
- W3185450136 hasLocation W31854501361 @default.
- W3185450136 hasLocation W31854501362 @default.
- W3185450136 hasOpenAccess W3185450136 @default.
- W3185450136 hasPrimaryLocation W31854501361 @default.
- W3185450136 hasRelatedWork W1984282923 @default.
- W3185450136 hasRelatedWork W2020898191 @default.
- W3185450136 hasRelatedWork W2091720821 @default.
- W3185450136 hasRelatedWork W2092246656 @default.
- W3185450136 hasRelatedWork W2373226427 @default.
- W3185450136 hasRelatedWork W2387456186 @default.
- W3185450136 hasRelatedWork W2388730008 @default.
- W3185450136 hasRelatedWork W3118107215 @default.
- W3185450136 hasRelatedWork W4318302263 @default.
- W3185450136 hasRelatedWork W757206253 @default.
- W3185450136 hasVolume "14" @default.
- W3185450136 isParatext "false" @default.
- W3185450136 isRetracted "false" @default.
- W3185450136 magId "3185450136" @default.
- W3185450136 workType "article" @default.