FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3185473531> ?p ?o ?g. }

• W3185473531 abstract "Object In the light of an aging population and ongoing advances in cancer control, the optimal management in geriatric patients with brain metastases (BM) poses an increasing challenge, especially due to the scarce data available. We therefore analyzed our institutional data with regard to factors influencing overall survival (OS) in geriatric patients with BM. Methods Between 2013 and 2018, patients aged ≥ 65 years with surgically treated BM were included in this retrospective analysis. In search of preoperatively identifiable risk factors for poor OS, in addition to the underlying cancer, the preoperative frailty of patients was analyzed using the modified Frailty Index (mFI). Results A total of 180 geriatric patients with surgically treated BM were identified. Geriatric patients categorized as least-frail achieved a median OS of 18 months, whereas frailest patients achieved an OS of only 3 months (p&lt;0.0001). Multivariable cox regression analysis detected “multiple intracranial metastases” (p=0.001), “infratentorial localization” (p=0.011), “preoperative CRP &gt;5 mg/l” (p=0.01) and “frailest patients (mFI ≥ 0.27)” (p=0.002) as predictors for reduced OS in older patients undergoing surgical treatment for BM. Conclusions In this retrospective series, pre-operative frailty was associated with poor survival in elderly patients with BM requiring surgery. Our analyses warrant thorough counselling and support of affected elderly patients and their families." @default.
• W3185473531 created "2021-08-02" @default.
• W3185473531 creator A5000038661 @default.
• W3185473531 creator A5005095447 @default.
• W3185473531 creator A5006223192 @default.
• W3185473531 creator A5008640562 @default.
• W3185473531 creator A5019276321 @default.
• W3185473531 creator A5023557457 @default.
• W3185473531 creator A5024876270 @default.
• W3185473531 creator A5024898063 @default.
• W3185473531 creator A5043083018 @default.
• W3185473531 creator A5044703028 @default.
• W3185473531 creator A5045953237 @default.
• W3185473531 creator A5055831369 @default.
• W3185473531 creator A5062796171 @default.
• W3185473531 creator A5065222436 @default.
• W3185473531 creator A5066290988 @default.
• W3185473531 creator A5072626081 @default.
• W3185473531 creator A5075311995 @default.
• W3185473531 creator A5083688199 @default.
• W3185473531 creator A5084473005 @default.
• W3185473531 date "2021-07-26" @default.
• W3185473531 modified "2023-10-11" @default.
• W3185473531 title "Outcome of Elderly Patients With Surgically Treated Brain Metastases" @default.
• W3185473531 cites W1890384891 @default.
• W3185473531 cites W1987771761 @default.
• W3185473531 cites W2004657944 @default.
• W3185473531 cites W2030584055 @default.
• W3185473531 cites W2040542758 @default.
• W3185473531 cites W2132143053 @default.
• W3185473531 cites W2132495825 @default.
• W3185473531 cites W2132853322 @default.
• W3185473531 cites W2159230388 @default.
• W3185473531 cites W2284892973 @default.
• W3185473531 cites W2590066015 @default.
• W3185473531 cites W2590692105 @default.
• W3185473531 cites W2604543566 @default.
• W3185473531 cites W2610725200 @default.
• W3185473531 cites W2809544134 @default.
• W3185473531 cites W2909598849 @default.
• W3185473531 cites W2940425264 @default.
• W3185473531 cites W3038009775 @default.
• W3185473531 cites W3084103030 @default.
• W3185473531 cites W3090960060 @default.
• W3185473531 cites W3091122809 @default.
• W3185473531 cites W3094873097 @default.
• W3185473531 cites W3106951198 @default.
• W3185473531 cites W3128523684 @default.
• W3185473531 doi "https://doi.org/10.3389/fonc.2021.713965" @default.
• W3185473531 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8350563" @default.
• W3185473531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34381733" @default.
• W3185473531 hasPublicationYear "2021" @default.
• W3185473531 type Work @default.
• W3185473531 sameAs 3185473531 @default.
• W3185473531 citedByCount "9" @default.
• W3185473531 countsByYear W31854735312021 @default.
• W3185473531 countsByYear W31854735312022 @default.
• W3185473531 countsByYear W31854735312023 @default.
• W3185473531 crossrefType "journal-article" @default.
• W3185473531 hasAuthorship W3185473531A5000038661 @default.
• W3185473531 hasAuthorship W3185473531A5005095447 @default.
• W3185473531 hasAuthorship W3185473531A5006223192 @default.
• W3185473531 hasAuthorship W3185473531A5008640562 @default.
• W3185473531 hasAuthorship W3185473531A5019276321 @default.
• W3185473531 hasAuthorship W3185473531A5023557457 @default.
• W3185473531 hasAuthorship W3185473531A5024876270 @default.
• W3185473531 hasAuthorship W3185473531A5024898063 @default.
• W3185473531 hasAuthorship W3185473531A5043083018 @default.
• W3185473531 hasAuthorship W3185473531A5044703028 @default.
• W3185473531 hasAuthorship W3185473531A5045953237 @default.
• W3185473531 hasAuthorship W3185473531A5055831369 @default.
• W3185473531 hasAuthorship W3185473531A5062796171 @default.
• W3185473531 hasAuthorship W3185473531A5065222436 @default.
• W3185473531 hasAuthorship W3185473531A5066290988 @default.
• W3185473531 hasAuthorship W3185473531A5072626081 @default.
• W3185473531 hasAuthorship W3185473531A5075311995 @default.
• W3185473531 hasAuthorship W3185473531A5083688199 @default.
• W3185473531 hasAuthorship W3185473531A5084473005 @default.
• W3185473531 hasBestOaLocation W31854735311 @default.
• W3185473531 hasConcept C121608353 @default.
• W3185473531 hasConcept C126322002 @default.
• W3185473531 hasConcept C141071460 @default.
• W3185473531 hasConcept C167135981 @default.
• W3185473531 hasConcept C2908647359 @default.
• W3185473531 hasConcept C50382708 @default.
• W3185473531 hasConcept C71924100 @default.
• W3185473531 hasConcept C99454951 @default.
• W3185473531 hasConceptScore W3185473531C121608353 @default.
• W3185473531 hasConceptScore W3185473531C126322002 @default.
• W3185473531 hasConceptScore W3185473531C141071460 @default.
• W3185473531 hasConceptScore W3185473531C167135981 @default.
• W3185473531 hasConceptScore W3185473531C2908647359 @default.
• W3185473531 hasConceptScore W3185473531C50382708 @default.
• W3185473531 hasConceptScore W3185473531C71924100 @default.
• W3185473531 hasConceptScore W3185473531C99454951 @default.
• W3185473531 hasLocation W31854735311 @default.
• W3185473531 hasLocation W31854735312 @default.
• W3185473531 hasLocation W31854735313 @default.
• W3185473531 hasOpenAccess W3185473531 @default.
• W3185473531 hasPrimaryLocation W31854735311 @default.

• next