FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3186181859> ?p ?o ?g. }

• W3186181859 endingPage "550" @default.
• W3186181859 startingPage "540" @default.
• W3186181859 abstract "In this study, magnetic O-carboxymethyl chitosan (MOCC) nanocomposite was synthesized and characterized as a drug delivery system for loading the anticancer drug irinotecan (CPT-11). To increase the drug loading capacity, MOCC was synthesized by linking the carboxyl group functionally to chitosan. Also, several critical factors such as concentration, the dose of MOCC, and contact time for optimum drug loading condition were investigated. The loading capacity of CPT-11 onto MOCC was calculated as 5.6 mg/g, and the loaded drug concentration was calculated as 0.04787 mM at pH value of 5. Besides, the cytotoxic properties of MOCC, CPT- 11 loaded MOCC (MOCC-CPT-11), and free CPT-11 were studied on glioblastoma multiforme cell lines, including U87 and U373. According to the results, the MOCC-CPT-11 showed at least as toxic effect as free CPT-11 even at very low concentrations, while the MOCC showed slight toxicity (cell viability of 96% to 78%) on U373 cell lines at all concentrations and for 24 h and 48 h incubation times. Moreover, the results showed that the MOCC indicated significant toxicity in increasing concentrations and incubation times, and the MOCC-CPT-11 is as toxic as free CPT-11 on U87 cells at all concentrations and incubation times." @default.
• W3186181859 created "2021-08-02" @default.
• W3186181859 creator A5087156077 @default.
• W3186181859 date "2021-06-30" @default.
• W3186181859 modified "2023-10-10" @default.
• W3186181859 title "Synthesis and characterization of magnetic nanocomposite for in vitro evaluation of irinotecan using human cell lines" @default.
• W3186181859 cites W1968867009 @default.
• W3186181859 cites W1975514668 @default.
• W3186181859 cites W2009189849 @default.
• W3186181859 cites W2009737103 @default.
• W3186181859 cites W2015442009 @default.
• W3186181859 cites W2017456485 @default.
• W3186181859 cites W2020704807 @default.
• W3186181859 cites W2039051826 @default.
• W3186181859 cites W2047173930 @default.
• W3186181859 cites W2051399816 @default.
• W3186181859 cites W2058521348 @default.
• W3186181859 cites W2067242125 @default.
• W3186181859 cites W2068871092 @default.
• W3186181859 cites W2076148552 @default.
• W3186181859 cites W2076739690 @default.
• W3186181859 cites W2119942076 @default.
• W3186181859 cites W2135396719 @default.
• W3186181859 cites W2163887121 @default.
• W3186181859 cites W2329918173 @default.
• W3186181859 cites W2333693843 @default.
• W3186181859 cites W2338521956 @default.
• W3186181859 cites W2738341638 @default.
• W3186181859 cites W2772371813 @default.
• W3186181859 cites W2894655398 @default.
• W3186181859 cites W2902965611 @default.
• W3186181859 cites W2918094477 @default.
• W3186181859 doi "https://doi.org/10.3906/kim-2010-53" @default.
• W3186181859 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8326468" @default.
• W3186181859 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34385850" @default.
• W3186181859 hasPublicationYear "2021" @default.
• W3186181859 type Work @default.
• W3186181859 sameAs 3186181859 @default.
• W3186181859 citedByCount "2" @default.
• W3186181859 countsByYear W31861818592022 @default.
• W3186181859 crossrefType "journal-article" @default.
• W3186181859 hasAuthorship W3186181859A5087156077 @default.
• W3186181859 hasBestOaLocation W31861818591 @default.
• W3186181859 hasConcept C121608353 @default.
• W3186181859 hasConcept C126322002 @default.
• W3186181859 hasConcept C13965031 @default.
• W3186181859 hasConcept C154317977 @default.
• W3186181859 hasConcept C171250308 @default.
• W3186181859 hasConcept C178790620 @default.
• W3186181859 hasConcept C185592680 @default.
• W3186181859 hasConcept C192562407 @default.
• W3186181859 hasConcept C202751555 @default.
• W3186181859 hasConcept C25642318 @default.
• W3186181859 hasConcept C2779682216 @default.
• W3186181859 hasConcept C2779732960 @default.
• W3186181859 hasConcept C2779820397 @default.
• W3186181859 hasConcept C2780035454 @default.
• W3186181859 hasConcept C2780259306 @default.
• W3186181859 hasConcept C29730261 @default.
• W3186181859 hasConcept C526805850 @default.
• W3186181859 hasConcept C53227056 @default.
• W3186181859 hasConcept C54355233 @default.
• W3186181859 hasConcept C55493867 @default.
• W3186181859 hasConcept C71924100 @default.
• W3186181859 hasConcept C81885089 @default.
• W3186181859 hasConcept C86803240 @default.
• W3186181859 hasConcept C92880739 @default.
• W3186181859 hasConcept C98274493 @default.
• W3186181859 hasConceptScore W3186181859C121608353 @default.
• W3186181859 hasConceptScore W3186181859C126322002 @default.
• W3186181859 hasConceptScore W3186181859C13965031 @default.
• W3186181859 hasConceptScore W3186181859C154317977 @default.
• W3186181859 hasConceptScore W3186181859C171250308 @default.
• W3186181859 hasConceptScore W3186181859C178790620 @default.
• W3186181859 hasConceptScore W3186181859C185592680 @default.
• W3186181859 hasConceptScore W3186181859C192562407 @default.
• W3186181859 hasConceptScore W3186181859C202751555 @default.
• W3186181859 hasConceptScore W3186181859C25642318 @default.
• W3186181859 hasConceptScore W3186181859C2779682216 @default.
• W3186181859 hasConceptScore W3186181859C2779732960 @default.
• W3186181859 hasConceptScore W3186181859C2779820397 @default.
• W3186181859 hasConceptScore W3186181859C2780035454 @default.
• W3186181859 hasConceptScore W3186181859C2780259306 @default.
• W3186181859 hasConceptScore W3186181859C29730261 @default.
• W3186181859 hasConceptScore W3186181859C526805850 @default.
• W3186181859 hasConceptScore W3186181859C53227056 @default.
• W3186181859 hasConceptScore W3186181859C54355233 @default.
• W3186181859 hasConceptScore W3186181859C55493867 @default.
• W3186181859 hasConceptScore W3186181859C71924100 @default.
• W3186181859 hasConceptScore W3186181859C81885089 @default.
• W3186181859 hasConceptScore W3186181859C86803240 @default.
• W3186181859 hasConceptScore W3186181859C92880739 @default.
• W3186181859 hasConceptScore W3186181859C98274493 @default.
• W3186181859 hasIssue "3" @default.
• W3186181859 hasLocation W31861818591 @default.
• W3186181859 hasLocation W31861818592 @default.
• W3186181859 hasOpenAccess W3186181859 @default.
• W3186181859 hasPrimaryLocation W31861818591 @default.

• next