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- W3186184564 startingPage "7529" @default.
- W3186184564 abstract "The mandibular and hyoid arches collectively make up the facial skeleton, also known as the viscerocranium. Although all three germ layers come together to assemble the pharyngeal arches, the majority of tissue within viscerocranial skeletal components differentiates from the neural crest. Since nearly one third of all birth defects in humans affect the craniofacial region, it is important to understand how signalling pathways and transcription factors govern the embryogenesis and skeletogenesis of the viscerocranium. This review focuses on mouse and zebrafish models of craniofacial development. We highlight gene regulatory networks directing the patterning and osteochondrogenesis of the mandibular and hyoid arches that are actually conserved among all gnathostomes. The first part of this review describes the anatomy and development of mandibular and hyoid arches in both species. The second part analyses cell signalling and transcription factors that ensure the specificity of individual structures along the anatomical axes. The third part discusses the genes and molecules that control the formation of bone and cartilage within mandibular and hyoid arches and how dysregulation of molecular signalling influences the development of skeletal components of the viscerocranium. In conclusion, we notice that mandibular malformations in humans and mice often co-occur with hyoid malformations and pinpoint the similar molecular machinery controlling the development of mandibular and hyoid arches." @default.
- W3186184564 created "2021-08-02" @default.
- W3186184564 creator A5026867764 @default.
- W3186184564 creator A5057554463 @default.
- W3186184564 creator A5079052985 @default.
- W3186184564 date "2021-07-14" @default.
- W3186184564 modified "2023-09-27" @default.
- W3186184564 title "The Mandibular and Hyoid Arches—From Molecular Patterning to Shaping Bone and Cartilage" @default.
- W3186184564 cites W1489648704 @default.
- W3186184564 cites W1514938989 @default.
- W3186184564 cites W1567849592 @default.
- W3186184564 cites W1574722884 @default.
- W3186184564 cites W1577043447 @default.
- W3186184564 cites W1586293351 @default.
- W3186184564 cites W1589165482 @default.
- W3186184564 cites W1591904091 @default.
- W3186184564 cites W1594381616 @default.
- W3186184564 cites W1602845636 @default.
- W3186184564 cites W1662926935 @default.
- W3186184564 cites W1739726394 @default.
- W3186184564 cites W1835943580 @default.
- W3186184564 cites W1852221350 @default.
- W3186184564 cites W1868736045 @default.
- W3186184564 cites W1872961786 @default.
- W3186184564 cites W1878061663 @default.
- W3186184564 cites W1903692288 @default.
- W3186184564 cites W1937527608 @default.
- W3186184564 cites W1951644352 @default.
- W3186184564 cites W1952493686 @default.
- W3186184564 cites W1955467086 @default.
- W3186184564 cites W1957261087 @default.
- W3186184564 cites W1958621441 @default.
- W3186184564 cites W1963565699 @default.
- W3186184564 cites W1963641861 @default.
- W3186184564 cites W1964394950 @default.
- W3186184564 cites W1965307323 @default.
- W3186184564 cites W1965624280 @default.
- W3186184564 cites W1966978229 @default.
- W3186184564 cites W1966991778 @default.
- W3186184564 cites W1968199309 @default.
- W3186184564 cites W1968353452 @default.
- W3186184564 cites W1968627658 @default.
- W3186184564 cites W1969588574 @default.
- W3186184564 cites W1973069947 @default.
- W3186184564 cites W1974052480 @default.
- W3186184564 cites W1974202557 @default.
- W3186184564 cites W1978056884 @default.
- W3186184564 cites W1979299296 @default.
- W3186184564 cites W1979892487 @default.
- W3186184564 cites W1980880596 @default.
- W3186184564 cites W1981048058 @default.
- W3186184564 cites W1981242420 @default.
- W3186184564 cites W1981284961 @default.
- W3186184564 cites W1982202488 @default.
- W3186184564 cites W1982292830 @default.
- W3186184564 cites W1982532675 @default.
- W3186184564 cites W1983977621 @default.
- W3186184564 cites W1984309369 @default.
- W3186184564 cites W1985502171 @default.
- W3186184564 cites W1985648832 @default.
- W3186184564 cites W1986072053 @default.
- W3186184564 cites W1989789172 @default.
- W3186184564 cites W1990851216 @default.
- W3186184564 cites W1990880194 @default.
- W3186184564 cites W1991295238 @default.
- W3186184564 cites W1992109292 @default.
- W3186184564 cites W1992898567 @default.
- W3186184564 cites W1993163303 @default.
- W3186184564 cites W1993528036 @default.
- W3186184564 cites W1994255894 @default.
- W3186184564 cites W1994596418 @default.
- W3186184564 cites W1995397565 @default.
- W3186184564 cites W1997441621 @default.
- W3186184564 cites W1997812904 @default.
- W3186184564 cites W1998271982 @default.
- W3186184564 cites W1999526532 @default.
- W3186184564 cites W1999601285 @default.
- W3186184564 cites W2001584235 @default.
- W3186184564 cites W2002246203 @default.
- W3186184564 cites W2002815733 @default.
- W3186184564 cites W2003971855 @default.
- W3186184564 cites W2004817003 @default.
- W3186184564 cites W2007123568 @default.
- W3186184564 cites W2009998759 @default.
- W3186184564 cites W2012765331 @default.
- W3186184564 cites W2013536234 @default.
- W3186184564 cites W2015486300 @default.
- W3186184564 cites W2017736681 @default.
- W3186184564 cites W2019366181 @default.
- W3186184564 cites W2019972895 @default.
- W3186184564 cites W2022221183 @default.
- W3186184564 cites W2022395088 @default.
- W3186184564 cites W2022429701 @default.
- W3186184564 cites W2022853418 @default.
- W3186184564 cites W2023169776 @default.
- W3186184564 cites W2024963992 @default.
- W3186184564 cites W2025046506 @default.
- W3186184564 cites W2028470685 @default.