Matches in SemOpenAlex for { <https://semopenalex.org/work/W3186263397> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W3186263397 abstract "Abstract Purpose Partial-volume correction (PVC) using the Geometric Transfer Matrix (GTM) method is used in positron emission tomography (PET) to compensate for the effects of spatial resolution on quantitation. We evaluate the effect of misspecification of scanner point-spread function (PSF) on GTM results in amyloid imaging, including the effect on amyloid status classification (positive or negative). Methods Twenty-nine subjects with Pittsburgh Compound B ([ 11 C]PiB) PET and structural T1 MR imaging were analyzed. FreeSurfer 5.3 (FS) was used to parcellate MR images into regions-of-interest (ROIs) that were used to extract radioactivity concentration values from the PET images. GTM PVC was performed using our “standard” PSF parameterization [3D Gaussian, full-width at half-maximum ( w ) of approximately 5 mm]. Additional GTM PVC was performed with “incorrect” parameterizations, taken around the correct value. The result is a set of regional activity values for each of the GTM applications. For each case, activity values from various ROIs were combined and normalized to produce standardized uptake value ratios (SUVRs) for nine standard [ 11 C]PiB quantitation ROIs and a global region. GTM operating-point characteristics were determined from the slope of apparent SUVR versus w curves. Results Errors in specification of w on the order of 1 mm (3D) mainly produce only modest errors of up to a few percent. An exception was the anterior ventral striatum in which fractional errors of up to 0.29 per millimeter (3D) of error in w were observed. Conclusion While this study does not address all the issues regarding the quantitative strengths and weakness of GTM PVC, we find that with reasonable caution, the unavoidable inaccuracies associated with PSF specification do not preclude its use in amyloid quantitation." @default.
- W3186263397 created "2021-08-02" @default.
- W3186263397 creator A5001794663 @default.
- W3186263397 creator A5011455214 @default.
- W3186263397 creator A5024995302 @default.
- W3186263397 creator A5050516079 @default.
- W3186263397 creator A5056508217 @default.
- W3186263397 creator A5057414041 @default.
- W3186263397 creator A5071138596 @default.
- W3186263397 date "2021-07-20" @default.
- W3186263397 modified "2023-10-14" @default.
- W3186263397 title "Characterization of point-spread function specification error on Geometric Transfer Matrix partial volume correction in [11C]PiB amyloid imaging" @default.
- W3186263397 cites W1866924806 @default.
- W3186263397 cites W1977460152 @default.
- W3186263397 cites W1982706910 @default.
- W3186263397 cites W2047284752 @default.
- W3186263397 cites W2075119726 @default.
- W3186263397 cites W2084954638 @default.
- W3186263397 cites W2090592015 @default.
- W3186263397 cites W2120892458 @default.
- W3186263397 cites W2150468784 @default.
- W3186263397 cites W2281358382 @default.
- W3186263397 cites W2340076687 @default.
- W3186263397 cites W2395989253 @default.
- W3186263397 cites W2508678417 @default.
- W3186263397 cites W2542549468 @default.
- W3186263397 cites W2708404124 @default.
- W3186263397 cites W2795933399 @default.
- W3186263397 cites W2802304700 @default.
- W3186263397 cites W2900550914 @default.
- W3186263397 cites W2948007219 @default.
- W3186263397 cites W3027825454 @default.
- W3186263397 cites W3084744208 @default.
- W3186263397 doi "https://doi.org/10.1186/s40658-021-00403-5" @default.
- W3186263397 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8292473" @default.
- W3186263397 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34283320" @default.
- W3186263397 hasPublicationYear "2021" @default.
- W3186263397 type Work @default.
- W3186263397 sameAs 3186263397 @default.
- W3186263397 citedByCount "0" @default.
- W3186263397 crossrefType "journal-article" @default.
- W3186263397 hasAuthorship W3186263397A5001794663 @default.
- W3186263397 hasAuthorship W3186263397A5011455214 @default.
- W3186263397 hasAuthorship W3186263397A5024995302 @default.
- W3186263397 hasAuthorship W3186263397A5050516079 @default.
- W3186263397 hasAuthorship W3186263397A5056508217 @default.
- W3186263397 hasAuthorship W3186263397A5057414041 @default.
- W3186263397 hasAuthorship W3186263397A5071138596 @default.
- W3186263397 hasBestOaLocation W31862633971 @default.
- W3186263397 hasConcept C121332964 @default.
- W3186263397 hasConcept C153180895 @default.
- W3186263397 hasConcept C154945302 @default.
- W3186263397 hasConcept C163716315 @default.
- W3186263397 hasConcept C199374082 @default.
- W3186263397 hasConcept C2775842073 @default.
- W3186263397 hasConcept C2989005 @default.
- W3186263397 hasConcept C33923547 @default.
- W3186263397 hasConcept C41008148 @default.
- W3186263397 hasConcept C46141821 @default.
- W3186263397 hasConcept C62520636 @default.
- W3186263397 hasConcept C69179731 @default.
- W3186263397 hasConcept C71924100 @default.
- W3186263397 hasConcept C82233179 @default.
- W3186263397 hasConceptScore W3186263397C121332964 @default.
- W3186263397 hasConceptScore W3186263397C153180895 @default.
- W3186263397 hasConceptScore W3186263397C154945302 @default.
- W3186263397 hasConceptScore W3186263397C163716315 @default.
- W3186263397 hasConceptScore W3186263397C199374082 @default.
- W3186263397 hasConceptScore W3186263397C2775842073 @default.
- W3186263397 hasConceptScore W3186263397C2989005 @default.
- W3186263397 hasConceptScore W3186263397C33923547 @default.
- W3186263397 hasConceptScore W3186263397C41008148 @default.
- W3186263397 hasConceptScore W3186263397C46141821 @default.
- W3186263397 hasConceptScore W3186263397C62520636 @default.
- W3186263397 hasConceptScore W3186263397C69179731 @default.
- W3186263397 hasConceptScore W3186263397C71924100 @default.
- W3186263397 hasConceptScore W3186263397C82233179 @default.
- W3186263397 hasFunder F4320337337 @default.
- W3186263397 hasIssue "1" @default.
- W3186263397 hasLocation W31862633971 @default.
- W3186263397 hasLocation W31862633972 @default.
- W3186263397 hasOpenAccess W3186263397 @default.
- W3186263397 hasPrimaryLocation W31862633971 @default.
- W3186263397 hasRelatedWork W1988232503 @default.
- W3186263397 hasRelatedWork W1991553034 @default.
- W3186263397 hasRelatedWork W2060802393 @default.
- W3186263397 hasRelatedWork W2117290479 @default.
- W3186263397 hasRelatedWork W2156996716 @default.
- W3186263397 hasRelatedWork W2169571869 @default.
- W3186263397 hasRelatedWork W2183007308 @default.
- W3186263397 hasRelatedWork W3021922582 @default.
- W3186263397 hasRelatedWork W3111531113 @default.
- W3186263397 hasRelatedWork W4376645205 @default.
- W3186263397 hasVolume "8" @default.
- W3186263397 isParatext "false" @default.
- W3186263397 isRetracted "false" @default.
- W3186263397 magId "3186263397" @default.
- W3186263397 workType "article" @default.