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• W3186276046 endingPage "127249" @default.
• W3186276046 startingPage "127249" @default.
• W3186276046 abstract "In recent years, electrochemical biosensors have been widely used in health care, and, due to the increasing demand for their use, new sensing performance requirements have been proposed. Widening detection range and speeding up response rate while improving the sensitivity of these sensors is a major current challenge. In this study, a high-performance three-dimensional (3D) non-enzymatic hydrogen peroxide biosensor was fabricated based on a simple photolithographic process. Neatly arranged cylindrical microarrays (MA) with clear edges were fabricated using SU-8 photoresist. Subsequently, a gold thin film was sputtered onto the MA to form a 3D Au/microarray electrode (Au/MAE). Additionally, we investigated the optimal size of the MA (aspect ratio = 2, diameter = 30 µm) required to obtain an Au/MAE with the best electron transfer properties. Based on these results, a 3D CuNPs/Au/MAE sensor was constructed via the electrochemical in-situ reduction of copper nanoparticles (CuNPs). Due to its increased specific surface area and contact sites, this 3D sensor with high stability and good selectivity for detecting hydrogen peroxide exhibited higher sensitivity and wider range of detection than 2D CuNPs/AuE sensor. Consequently, the design of 3D microarray structure provides a new strategy for the fabrication of high-performance sensors that can be used in clinical applications." @default.
• W3186276046 created "2021-08-02" @default.
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• W3186276046 date "2021-11-01" @default.
• W3186276046 modified "2023-10-16" @default.
• W3186276046 title "Photolithographic 3D microarray electrode-based high-performance non-enzymatic H2O2 sensor" @default.
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• W3186276046 doi "https://doi.org/10.1016/j.colsurfa.2021.127249" @default.
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