Matches in SemOpenAlex for { <https://semopenalex.org/work/W3186285311> ?p ?o ?g. }
- W3186285311 abstract "Previous studies have identified altered brain changes in chronic pain patients, however, it remains unclear whether these changes are reversible. We summarized the neural and molecular changes in patients with chronic pain and employed a meta-analysis approach to quantify the changes. We included 75 studies and 11 of these 75 studies were included in the activation likelihood estimation (ALE) analysis. In the 62 functional magnetic resonance imaging (fMRI) studies, the primary somatosensory and motor cortex (SI and MI), thalamus, insula, and anterior cingulate cortex (ACC) showed significantly decreased activity after the treatments compared to baseline. In the 13 positron emission tomography (PET) studies, the SI, MI, thalamus, and insula showed significantly increased glucose uptake, blood flow, and opioid-receptor binding potentials after the treatments compared to baseline. A meta-analysis of fMRI studies in patients with chronic pain, during pain-related tasks, showed a significant deactivation likelihood cluster in the left medial posterior thalamus. Further studies are warranted to understand brain reorganization in patients with chronic pain compared to the normal state, in terms of its relationship with symptom reduction and baseline conditions." @default.
- W3186285311 created "2021-08-02" @default.
- W3186285311 creator A5001438710 @default.
- W3186285311 creator A5037234491 @default.
- W3186285311 creator A5044840923 @default.
- W3186285311 creator A5063012497 @default.
- W3186285311 date "2021-07-05" @default.
- W3186285311 modified "2023-10-14" @default.
- W3186285311 title "Effects of Chronic Pain Treatment on Altered Functional and Metabolic Activities in the Brain: A Systematic Review and Meta-Analysis of Functional Neuroimaging Studies" @default.
- W3186285311 cites W118709841 @default.
- W3186285311 cites W1434429402 @default.
- W3186285311 cites W1539729845 @default.
- W3186285311 cites W1664843084 @default.
- W3186285311 cites W1706861413 @default.
- W3186285311 cites W1822627911 @default.
- W3186285311 cites W1905800278 @default.
- W3186285311 cites W1923402420 @default.
- W3186285311 cites W1943020141 @default.
- W3186285311 cites W1962885651 @default.
- W3186285311 cites W1965011560 @default.
- W3186285311 cites W1967059019 @default.
- W3186285311 cites W1967539853 @default.
- W3186285311 cites W1968280685 @default.
- W3186285311 cites W1975413521 @default.
- W3186285311 cites W1975953969 @default.
- W3186285311 cites W1976859826 @default.
- W3186285311 cites W1978184324 @default.
- W3186285311 cites W1978733227 @default.
- W3186285311 cites W1979233603 @default.
- W3186285311 cites W1990523428 @default.
- W3186285311 cites W1990532043 @default.
- W3186285311 cites W1991703590 @default.
- W3186285311 cites W1999460576 @default.
- W3186285311 cites W2002869923 @default.
- W3186285311 cites W2005501262 @default.
- W3186285311 cites W2013467215 @default.
- W3186285311 cites W2013670672 @default.
- W3186285311 cites W2014189974 @default.
- W3186285311 cites W2017404787 @default.
- W3186285311 cites W2019887498 @default.
- W3186285311 cites W2022271485 @default.
- W3186285311 cites W2026049606 @default.
- W3186285311 cites W2027304361 @default.
- W3186285311 cites W2029985169 @default.
- W3186285311 cites W2039434037 @default.
- W3186285311 cites W2044491272 @default.
- W3186285311 cites W2045895137 @default.
- W3186285311 cites W2057880101 @default.
- W3186285311 cites W2059036933 @default.
- W3186285311 cites W2061845317 @default.
- W3186285311 cites W2068328649 @default.
- W3186285311 cites W2070600825 @default.
- W3186285311 cites W2072184329 @default.
- W3186285311 cites W2072579585 @default.
- W3186285311 cites W2072866578 @default.
- W3186285311 cites W2075715972 @default.
- W3186285311 cites W2078481810 @default.
- W3186285311 cites W2080108438 @default.
- W3186285311 cites W2080775247 @default.
- W3186285311 cites W2083722398 @default.
- W3186285311 cites W2086551541 @default.
- W3186285311 cites W2088035788 @default.
- W3186285311 cites W2101829719 @default.
- W3186285311 cites W2105740019 @default.
- W3186285311 cites W2105766914 @default.
- W3186285311 cites W2105824687 @default.
- W3186285311 cites W2110115849 @default.
- W3186285311 cites W2110895877 @default.
- W3186285311 cites W2113217511 @default.
- W3186285311 cites W2115676682 @default.
- W3186285311 cites W2116003026 @default.
- W3186285311 cites W2116230226 @default.
- W3186285311 cites W2123385438 @default.
- W3186285311 cites W2131165483 @default.
- W3186285311 cites W2138030673 @default.
- W3186285311 cites W2143994694 @default.
- W3186285311 cites W2148761681 @default.
- W3186285311 cites W2149421654 @default.
- W3186285311 cites W2150750435 @default.
- W3186285311 cites W2151183601 @default.
- W3186285311 cites W2151282185 @default.
- W3186285311 cites W2155524482 @default.
- W3186285311 cites W2156343006 @default.
- W3186285311 cites W2157094615 @default.
- W3186285311 cites W2157133757 @default.
- W3186285311 cites W2159386313 @default.
- W3186285311 cites W2159431069 @default.
- W3186285311 cites W2159936035 @default.
- W3186285311 cites W2161143743 @default.
- W3186285311 cites W2161630779 @default.
- W3186285311 cites W2162638563 @default.
- W3186285311 cites W2166255720 @default.
- W3186285311 cites W2167613032 @default.
- W3186285311 cites W2171946774 @default.
- W3186285311 cites W2209739872 @default.
- W3186285311 cites W2241603838 @default.
- W3186285311 cites W2293646806 @default.
- W3186285311 cites W2300966694 @default.
- W3186285311 cites W2302120737 @default.
- W3186285311 cites W2317056404 @default.