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- W3186331488 endingPage "903" @default.
- W3186331488 startingPage "903" @default.
- W3186331488 abstract "The Coronavirus 2 (SARS-CoV-2) infection is a global pandemic that has affected millions of people worldwide. The advent of vaccines has permitted some restitution. Aside from the respiratory complications of the infection, there is also a thrombotic risk attributed to both the disease and the vaccine. There are no reliable data for the risk of thromboembolism in SARS-CoV-2 infection in patients managed out of the hospital setting. A literature review was performed to identify the pathophysiological mechanism of thrombosis from the SARS-CoV-2 infection including the role of Angiotensin-Converting Enzyme receptors. The impact of the vaccine and likely mechanisms of thrombosis following vaccination were also clarified. Finally, the utility of the vaccines available against the multiple variants is also highlighted. The systemic response to SARS-CoV-2 infection is still relatively poorly understood, but several risk factors have been identified. The roll-out of the vaccines worldwide has also allowed the lifting of lockdown measures and a reduction in the spread of the disease. The experience of the SARS-CoV-2 infection, however, has highlighted the crucial role of epidemiological research and the need for ongoing studies within this field." @default.
- W3186331488 created "2021-08-02" @default.
- W3186331488 creator A5032173063 @default.
- W3186331488 creator A5059592891 @default.
- W3186331488 creator A5081478632 @default.
- W3186331488 date "2021-07-27" @default.
- W3186331488 modified "2023-09-27" @default.
- W3186331488 title "COVID-19 Pathogenesis: From Molecular Pathway to Vaccine Administration" @default.
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