FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3186377534> ?p ?o ?g. }

• W3186377534 abstract "Background: Intracranial atherosclerotic disease (ICAD) tends to affect multiple arterial segments, and previous studies rarely performed a comprehensive plaque analysis of the entire circle of Willis for the evaluation of recurrent stroke risk. We aimed to investigate the features of circle of Willis ICAD on 3D magnetic resonance vessel wall imaging (MR-VWI) and their relationships with recurrent acute stroke. Methods: Patients with either acute ischemic stroke (within 4 weeks after stroke) or chronic ischemic stroke (after 3 months of stroke) due to intracranial atherosclerotic plaque underwent 3D contrast-enhanced MR-VWI covering major cerebral arteries. Participants were divided into three groups: first-time acute stroke, recurrent acute stroke, and chronic stroke. Culprit plaque (defined as the only lesion or the most stenotic lesion when multiple plaques were present within the same vascular territory of the stroke) and non-culprit plaque characteristics, including total plaque number, plaque thickness, plaque area, plaque burden (calculated as plaque area divided by outer wall area), enhancement ratio (ER), eccentricity, and stenosis, were measured and compared across the three groups. Associations between plaque characteristics and recurrent acute stroke were investigated by multivariate analysis. Results: A total of 176 participants (aged 61 ± 10 years, 109 men) with 702 intracranial plaques were included in this study. There were 80 patients with first-time acute stroke, 42 patients with recurrent acute stroke, and 54 patients with chronic stroke. More intracranial plaques were found per patient in the recurrent acute stroke group than in the first-time acute stroke or chronic stroke group (5.19 ± 1.90 vs. 3.71 ± 1.96 and 3.46 ± 1.33, p &lt; 0.001). Patients in the recurrent acute stroke group had greater culprit plaque burden ( p &lt; 0.001) and higher culprit ER ( p &lt; 0.001) than the other two groups. After adjustment of clinical demographic factors, in multivariate analysis, coronary artery disease (CAD) (odds ratio, OR = 4.61; p = 0.035), total plaque number ( OR = 1.54; p = 0.003), culprit plaque ER ( OR = 2.50; p = 0.036), and culprit plaque burden ( OR per 10% increment = 2.44; p = 0.010) were all independently associated with recurrent acute stroke compared to the first-time acute stroke. Conclusion: Increased intracranial atherosclerotic plaque number, higher culprit plaque ER, greater culprit plaque burden, and CAD are independently associated with recurrent acute stroke." @default.
• W3186377534 created "2021-08-02" @default.
• W3186377534 creator A5001620453 @default.
• W3186377534 creator A5002461253 @default.
• W3186377534 creator A5004494857 @default.
• W3186377534 creator A5009822768 @default.
• W3186377534 creator A5014042142 @default.
• W3186377534 creator A5036900255 @default.
• W3186377534 creator A5046395110 @default.
• W3186377534 creator A5050745421 @default.
• W3186377534 creator A5050974013 @default.
• W3186377534 creator A5071667725 @default.
• W3186377534 creator A5073468737 @default.
• W3186377534 creator A5081008886 @default.
• W3186377534 creator A5088965321 @default.
• W3186377534 date "2021-07-28" @default.
• W3186377534 modified "2023-10-01" @default.
• W3186377534 title "Intracranial Atherosclerotic Plaque Characteristics and Burden Associated With Recurrent Acute Stroke: A 3D Quantitative Vessel Wall MRI Study" @default.
• W3186377534 cites W1830656716 @default.
• W3186377534 cites W1890361879 @default.
• W3186377534 cites W1979574276 @default.
• W3186377534 cites W1985816747 @default.
• W3186377534 cites W1995877209 @default.
• W3186377534 cites W2008037984 @default.
• W3186377534 cites W2015047751 @default.
• W3186377534 cites W2020394101 @default.
• W3186377534 cites W2029430836 @default.
• W3186377534 cites W2030403472 @default.
• W3186377534 cites W2050501652 @default.
• W3186377534 cites W2050683491 @default.
• W3186377534 cites W2061446661 @default.
• W3186377534 cites W2095584421 @default.
• W3186377534 cites W2098040462 @default.
• W3186377534 cites W2123634131 @default.
• W3186377534 cites W2128430814 @default.
• W3186377534 cites W2133963928 @default.
• W3186377534 cites W2145899334 @default.
• W3186377534 cites W2155782537 @default.
• W3186377534 cites W2156266161 @default.
• W3186377534 cites W2162891740 @default.
• W3186377534 cites W2163500049 @default.
• W3186377534 cites W2219104762 @default.
• W3186377534 cites W2227080759 @default.
• W3186377534 cites W2294967546 @default.
• W3186377534 cites W2344353791 @default.
• W3186377534 cites W2498943185 @default.
• W3186377534 cites W2553221222 @default.
• W3186377534 cites W2766369533 @default.
• W3186377534 cites W2776534022 @default.
• W3186377534 cites W2797200581 @default.
• W3186377534 cites W2803580639 @default.
• W3186377534 cites W2890742182 @default.
• W3186377534 cites W2892478521 @default.
• W3186377534 cites W2910465346 @default.
• W3186377534 cites W2913026733 @default.
• W3186377534 cites W2957606078 @default.
• W3186377534 cites W2982371991 @default.
• W3186377534 cites W2997521920 @default.
• W3186377534 cites W3005537925 @default.
• W3186377534 cites W3015190631 @default.
• W3186377534 cites W3016349990 @default.
• W3186377534 cites W3039564160 @default.
• W3186377534 cites W3045343817 @default.
• W3186377534 cites W3082879995 @default.
• W3186377534 cites W3131815228 @default.
• W3186377534 doi "https://doi.org/10.3389/fnagi.2021.706544" @default.
• W3186377534 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8355600" @default.
• W3186377534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34393761" @default.
• W3186377534 hasPublicationYear "2021" @default.
• W3186377534 type Work @default.
• W3186377534 sameAs 3186377534 @default.
• W3186377534 citedByCount "22" @default.
• W3186377534 countsByYear W31863775342022 @default.
• W3186377534 countsByYear W31863775342023 @default.
• W3186377534 crossrefType "journal-article" @default.
• W3186377534 hasAuthorship W3186377534A5001620453 @default.
• W3186377534 hasAuthorship W3186377534A5002461253 @default.
• W3186377534 hasAuthorship W3186377534A5004494857 @default.
• W3186377534 hasAuthorship W3186377534A5009822768 @default.
• W3186377534 hasAuthorship W3186377534A5014042142 @default.
• W3186377534 hasAuthorship W3186377534A5036900255 @default.
• W3186377534 hasAuthorship W3186377534A5046395110 @default.
• W3186377534 hasAuthorship W3186377534A5050745421 @default.
• W3186377534 hasAuthorship W3186377534A5050974013 @default.
• W3186377534 hasAuthorship W3186377534A5071667725 @default.
• W3186377534 hasAuthorship W3186377534A5073468737 @default.
• W3186377534 hasAuthorship W3186377534A5081008886 @default.
• W3186377534 hasAuthorship W3186377534A5088965321 @default.
• W3186377534 hasBestOaLocation W31863775341 @default.
• W3186377534 hasConcept C104317684 @default.
• W3186377534 hasConcept C118552586 @default.
• W3186377534 hasConcept C126322002 @default.
• W3186377534 hasConcept C126838900 @default.
• W3186377534 hasConcept C127413603 @default.
• W3186377534 hasConcept C141071460 @default.
• W3186377534 hasConcept C143409427 @default.
• W3186377534 hasConcept C164705383 @default.
• W3186377534 hasConcept C16568411 @default.
• W3186377534 hasConcept C185592680 @default.
• W3186377534 hasConcept C2776572282 @default.

• next