FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3186471085> ?p ?o ?g. }

• W3186471085 abstract "Difficulty in providing endoscopy for patients with iron deficiency anaemia (IDA) during the COVID-19 pandemic has highlighted the requirement for a prioritisation tool. We aimed to test the validity of qFIT as a prioritisation tool in patients with iron deficiency and its ability to identify patients with advanced neoplastic lesions (ANLs). Data collected from patients referred with biochemically proven iron deficiency (ferritin ≤ 15 μg/L) and synchronous qFIT who underwent full gastrointestinal investigation within NHS Greater Glasgow and Clyde was analysed retrospectively. Patients who did not undergo full investigation, defined as gastroscopy and colonoscopy or CT colonography, were excluded. ANLs were defined as defined as upper GI cancer, colorectal adenoma ≥ 1 cm or colorectal cancer. Area under the curve (AUC) analysis was performed on qFIT results and outcome, defined as the presence of an ANL. AUC analysis guided cut-off scores for qFIT. Patients with a qFIT of &lt;10, 10–200, &gt;200, were allocated a score of 1, 2, and 3, respectively. A total of 575 patients met criteria for inclusion into the study. Overall, qFIT results strongly predicted the presence of ANLs (AUC 0.87, CI 0.81–0.92; P &lt; 0.001). The prevalence of ANLs in patients with scores 1–3 was 1.2, 13.5, and 38.9% respectfully. When controlled for other significant variables, patients with a higher qFIT score were statistically more likely to have an ANL (qFIT score = 2; OR 12.8; P &lt; 0.001, qFIT score = 3, OR 50.0; P &lt; 0.001). A negative qFIT had a high NPV for the presence of ANLs (98.8%, CI 97.0–99.5%). These results strongly suggest that qFIT has validity as a prioritisation tool in patients with iron deficiency; both allowing for a more informed decision of investigation of patients with very low risk of malignancy, and in identifying higher risk patients who may benefit from more urgent endoscopy." @default.
• W3186471085 created "2021-08-02" @default.
• W3186471085 creator A5007804720 @default.
• W3186471085 creator A5033858413 @default.
• W3186471085 creator A5066899261 @default.
• W3186471085 creator A5072113750 @default.
• W3186471085 date "2021-07-22" @default.
• W3186471085 modified "2023-09-26" @default.
• W3186471085 title "The Value of Quantitative Faecal Immunochemical Testing as a Prioritisation Tool for the Endoscopic Investigation of Patients With Iron Deficiency" @default.
• W3186471085 cites W2014718318 @default.
• W3186471085 cites W2020103304 @default.
• W3186471085 cites W2050899028 @default.
• W3186471085 cites W2068382972 @default.
• W3186471085 cites W2083417681 @default.
• W3186471085 cites W2145103423 @default.
• W3186471085 cites W2160432438 @default.
• W3186471085 cites W2163335071 @default.
• W3186471085 cites W2163361668 @default.
• W3186471085 cites W2163689545 @default.
• W3186471085 cites W2737862619 @default.
• W3186471085 cites W2743148460 @default.
• W3186471085 cites W2743872561 @default.
• W3186471085 cites W2785994793 @default.
• W3186471085 cites W2945127782 @default.
• W3186471085 cites W2991558703 @default.
• W3186471085 cites W2998835660 @default.
• W3186471085 cites W3000095306 @default.
• W3186471085 cites W3033521222 @default.
• W3186471085 cites W3041734480 @default.
• W3186471085 cites W3049350335 @default.
• W3186471085 cites W3077330533 @default.
• W3186471085 cites W3093155990 @default.
• W3186471085 doi "https://doi.org/10.3389/fmed.2021.700753" @default.
• W3186471085 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/8339881" @default.
• W3186471085 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34368194" @default.
• W3186471085 hasPublicationYear "2021" @default.
• W3186471085 type Work @default.
• W3186471085 sameAs 3186471085 @default.
• W3186471085 citedByCount "3" @default.
• W3186471085 countsByYear W31864710852022 @default.
• W3186471085 countsByYear W31864710852023 @default.
• W3186471085 crossrefType "journal-article" @default.
• W3186471085 hasAuthorship W3186471085A5007804720 @default.
• W3186471085 hasAuthorship W3186471085A5033858413 @default.
• W3186471085 hasAuthorship W3186471085A5066899261 @default.
• W3186471085 hasAuthorship W3186471085A5072113750 @default.
• W3186471085 hasBestOaLocation W31864710851 @default.
• W3186471085 hasConcept C121608353 @default.
• W3186471085 hasConcept C126322002 @default.
• W3186471085 hasConcept C2777417653 @default.
• W3186471085 hasConcept C2777428134 @default.
• W3186471085 hasConcept C2778248108 @default.
• W3186471085 hasConcept C2778319317 @default.
• W3186471085 hasConcept C2778435480 @default.
• W3186471085 hasConcept C2778451229 @default.
• W3186471085 hasConcept C526805850 @default.
• W3186471085 hasConcept C71924100 @default.
• W3186471085 hasConcept C90924648 @default.
• W3186471085 hasConceptScore W3186471085C121608353 @default.
• W3186471085 hasConceptScore W3186471085C126322002 @default.
• W3186471085 hasConceptScore W3186471085C2777417653 @default.
• W3186471085 hasConceptScore W3186471085C2777428134 @default.
• W3186471085 hasConceptScore W3186471085C2778248108 @default.
• W3186471085 hasConceptScore W3186471085C2778319317 @default.
• W3186471085 hasConceptScore W3186471085C2778435480 @default.
• W3186471085 hasConceptScore W3186471085C2778451229 @default.
• W3186471085 hasConceptScore W3186471085C526805850 @default.
• W3186471085 hasConceptScore W3186471085C71924100 @default.
• W3186471085 hasConceptScore W3186471085C90924648 @default.
• W3186471085 hasLocation W31864710851 @default.
• W3186471085 hasLocation W31864710852 @default.
• W3186471085 hasLocation W31864710853 @default.
• W3186471085 hasOpenAccess W3186471085 @default.
• W3186471085 hasPrimaryLocation W31864710851 @default.
• W3186471085 hasRelatedWork W11665586 @default.
• W3186471085 hasRelatedWork W1970829184 @default.
• W3186471085 hasRelatedWork W2074414654 @default.
• W3186471085 hasRelatedWork W2267760920 @default.
• W3186471085 hasRelatedWork W2318676174 @default.
• W3186471085 hasRelatedWork W2416484444 @default.
• W3186471085 hasRelatedWork W2417774362 @default.
• W3186471085 hasRelatedWork W2944981773 @default.
• W3186471085 hasRelatedWork W2949129511 @default.
• W3186471085 hasRelatedWork W3029016851 @default.
• W3186471085 hasVolume "8" @default.
• W3186471085 isParatext "false" @default.
• W3186471085 isRetracted "false" @default.
• W3186471085 magId "3186471085" @default.
• W3186471085 workType "article" @default.