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- W3186597188 abstract "HBsAg clearance can significantly reduce the risk of end-stage liver disease and liver cancer in patients with chronic hepatitis B; however, HBsAg clearance rate is very low, either by spontaneous clearance or antiviral therapy. This article summarizes the influencing factors for spontaneous clearance of HBsAg and HBsAg clearance after antiviral therapy and the durability of HBsAg clearance. In addition, this article reviews the potential of new drugs in development, such as nucleic acid polymers and immunomodulators, in HBsAg clearance, so as to provide clues for the clinical cure of chronic hepatitis B in the future." @default.
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- W3186597188 date "2021-07-20" @default.
- W3186597188 modified "2023-09-25" @default.
- W3186597188 title "Influencing factors for serum HBsAg clearance in people with chronic hepatitis B virus infection and its clinical significance" @default.
- W3186597188 doi "https://doi.org/10.3969/j.issn.1001-5256.2021.07.043" @default.
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