Matches in SemOpenAlex for { <https://semopenalex.org/work/W3186618918> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3186618918 abstract "Objectives: Hypoxia delays brain maturation and contributes to neurodevelopment morbidity in foetuses with congenital heart defects (CHD). Maternal hyperoxygenation (MH) can, in theory, promote oxygen/nutrient delivery to the foetal brain, owing to an improved heat structure/function and increased foetal oxygen content. We aimed to determine whether MH alters foetal cerebral hemodynamic in foetuses with CHD. Method: Twenty-eight foetuses with borderline small left hearts and 28 age-matched normal foetuses were enrolled and subdivided by gestational age (GA): 23+0~27+6 weeks and 28+0~36+6 weeks. The middle cerebral artery pulsatility index (MCA-PI), vascular index (VI), flow index (FI) and vascular/flow index (VFI) were measured with baseline room air, after 10 minutes of MH and after 10 minutes of recovery for all subjects. Results: MCA-PI, VI, FI and VFI did not differ with MH in the normal foetuses. A different pattern for the cerebral vascular response to MH was evident in foetuses with borderline small left hearts. MCA-PI increased and VI, FI and VFI decreased significantly during the 3rd trimester, but this response was not apparent during mid-gestation. These parameters returned to the baseline levels during the recovery phase. The change in cerebral perfusion depended on the baseline MCA-PI and increased the combined cardiac index (CCOi). Conclusion: MH alters the cerebral hemodynamic of some foetuses with borderline small left hearts during the third trimester. The current data suggest there may be potential negative effect of reducing cerebral blood flow and increasing cerebral vascular resistance. Funding Statement: This study was supported by the Natural Sciences Foundation of China (no. 81271593, 81501497).Declaration of Interests: The authors state: None declaredEthics Approval Statement: This study was approved by the institutional review board at the Second Xiangya Hospital of Central South University, and written informed consent was obtained from all families." @default.
- W3186618918 created "2021-08-02" @default.
- W3186618918 creator A5018903485 @default.
- W3186618918 creator A5048227001 @default.
- W3186618918 creator A5056519111 @default.
- W3186618918 creator A5086993924 @default.
- W3186618918 creator A5089224600 @default.
- W3186618918 creator A5089730971 @default.
- W3186618918 date "2019-01-01" @default.
- W3186618918 modified "2023-10-12" @default.
- W3186618918 title "Cerebral Hemodynamic Response to Short-Term Maternal Hyperoxygenation in Foetuses with Borderline Small Left Hearts" @default.
- W3186618918 doi "https://doi.org/10.2139/ssrn.3361160" @default.
- W3186618918 hasPublicationYear "2019" @default.
- W3186618918 type Work @default.
- W3186618918 sameAs 3186618918 @default.
- W3186618918 citedByCount "0" @default.
- W3186618918 crossrefType "journal-article" @default.
- W3186618918 hasAuthorship W3186618918A5018903485 @default.
- W3186618918 hasAuthorship W3186618918A5048227001 @default.
- W3186618918 hasAuthorship W3186618918A5056519111 @default.
- W3186618918 hasAuthorship W3186618918A5086993924 @default.
- W3186618918 hasAuthorship W3186618918A5089224600 @default.
- W3186618918 hasAuthorship W3186618918A5089730971 @default.
- W3186618918 hasConcept C126322002 @default.
- W3186618918 hasConcept C139940330 @default.
- W3186618918 hasConcept C154281038 @default.
- W3186618918 hasConcept C157767197 @default.
- W3186618918 hasConcept C164705383 @default.
- W3186618918 hasConcept C171614378 @default.
- W3186618918 hasConcept C172680121 @default.
- W3186618918 hasConcept C178790620 @default.
- W3186618918 hasConcept C178853913 @default.
- W3186618918 hasConcept C185592680 @default.
- W3186618918 hasConcept C2775841333 @default.
- W3186618918 hasConcept C2777031167 @default.
- W3186618918 hasConcept C2778376644 @default.
- W3186618918 hasConcept C2779234561 @default.
- W3186618918 hasConcept C31861589 @default.
- W3186618918 hasConcept C42219234 @default.
- W3186618918 hasConcept C46973012 @default.
- W3186618918 hasConcept C540031477 @default.
- W3186618918 hasConcept C541997718 @default.
- W3186618918 hasConcept C54355233 @default.
- W3186618918 hasConcept C58245268 @default.
- W3186618918 hasConcept C71924100 @default.
- W3186618918 hasConcept C7836513 @default.
- W3186618918 hasConcept C86803240 @default.
- W3186618918 hasConceptScore W3186618918C126322002 @default.
- W3186618918 hasConceptScore W3186618918C139940330 @default.
- W3186618918 hasConceptScore W3186618918C154281038 @default.
- W3186618918 hasConceptScore W3186618918C157767197 @default.
- W3186618918 hasConceptScore W3186618918C164705383 @default.
- W3186618918 hasConceptScore W3186618918C171614378 @default.
- W3186618918 hasConceptScore W3186618918C172680121 @default.
- W3186618918 hasConceptScore W3186618918C178790620 @default.
- W3186618918 hasConceptScore W3186618918C178853913 @default.
- W3186618918 hasConceptScore W3186618918C185592680 @default.
- W3186618918 hasConceptScore W3186618918C2775841333 @default.
- W3186618918 hasConceptScore W3186618918C2777031167 @default.
- W3186618918 hasConceptScore W3186618918C2778376644 @default.
- W3186618918 hasConceptScore W3186618918C2779234561 @default.
- W3186618918 hasConceptScore W3186618918C31861589 @default.
- W3186618918 hasConceptScore W3186618918C42219234 @default.
- W3186618918 hasConceptScore W3186618918C46973012 @default.
- W3186618918 hasConceptScore W3186618918C540031477 @default.
- W3186618918 hasConceptScore W3186618918C541997718 @default.
- W3186618918 hasConceptScore W3186618918C54355233 @default.
- W3186618918 hasConceptScore W3186618918C58245268 @default.
- W3186618918 hasConceptScore W3186618918C71924100 @default.
- W3186618918 hasConceptScore W3186618918C7836513 @default.
- W3186618918 hasConceptScore W3186618918C86803240 @default.
- W3186618918 hasLocation W31866189181 @default.
- W3186618918 hasOpenAccess W3186618918 @default.
- W3186618918 hasPrimaryLocation W31866189181 @default.
- W3186618918 hasRelatedWork W1995198804 @default.
- W3186618918 hasRelatedWork W2012553329 @default.
- W3186618918 hasRelatedWork W2015237380 @default.
- W3186618918 hasRelatedWork W2083657515 @default.
- W3186618918 hasRelatedWork W2138928882 @default.
- W3186618918 hasRelatedWork W2372528978 @default.
- W3186618918 hasRelatedWork W2384903451 @default.
- W3186618918 hasRelatedWork W3025048224 @default.
- W3186618918 hasRelatedWork W3186618918 @default.
- W3186618918 hasRelatedWork W4242586704 @default.
- W3186618918 isParatext "false" @default.
- W3186618918 isRetracted "false" @default.
- W3186618918 magId "3186618918" @default.
- W3186618918 workType "article" @default.