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- W3186648424 abstract "Magnesium (Mg) is commonly addressed as the forgotten ion in medicine. Nonetheless, hypomagnesemia should be suspected in clinical practice in patients with relevant symptomatology and also be considered a predisposing factor for the development of other electrolyte disturbances. Furthermore, chronic hypomagnesemia has been associated with diabetes mellitus and cardiovascular disease. Hypomagnesemia as a consequence of drug therapy is relatively common, with the list of drugs inducing low serum Mg levels expanding. Culprit medications linked to hypomagnesemia include antibiotics (e.g. aminoglycosides, amphotericin B), diuretics, antineoplastic drugs (cisplatin and cetuximab), calcineurin inhibitors, and proton pump inhibitors. In recent years, the mechanisms of drug-induced hypomagnesemia have been unraveled through the discovery of key Mg transporters in the gut and kidney. This narrative review of available literature focuses on the pathogenetic mechanisms underlying drug-induced hypomagnesemia in order to increase the insight of clinicians toward early diagnosis and effective management." @default.
- W3186648424 created "2021-08-02" @default.
- W3186648424 creator A5023738544 @default.
- W3186648424 creator A5027968873 @default.
- W3186648424 creator A5040151136 @default.
- W3186648424 creator A5056134447 @default.
- W3186648424 date "2021-07-18" @default.
- W3186648424 modified "2023-10-14" @default.
- W3186648424 title "An overview of diagnosis and management of drug‐induced hypomagnesemia" @default.
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